Protein Alignment Ugt303B2 and Ugt1a1

DIOPT Version :10

• Sequence 1: NP_651154.1
• Gene: Ugt303B2 / 42776
• FlyBaseID: FBgn0039087
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: NP_964007.2
• Gene: Ugt1a1 / 394436
• MGIID: 98898
• Length: 535
• Species: Mus musculus
• Alignment Length: 542
• Identity: 141/542 - (26%)
• Similarity: 239/542 - (44%)
• Gaps: 95/542 - (17%)

  Fly    12 LLLHLNLYLELGQAANILG---VFPYRIPSPFQMVRPLIKALVERGHKVTMVTP-ADYPAKIDG- 71
            |||...|....|.:|:..|   |||.. .|.:..:..:|:.|.::||:|.::.| |....| :|
Mouse    12 LLLPYLLLCVFGPSASHAGRLLVFPMD-GSHWLSMLGVIQQLQQKGHEVVVIAPEASIHIK-EGS 74

  Fly    72 ---VRHIRVPM--------LNQLMQNLMKNDQFFDALGDKWREGVLVSTIFYNVSHAILNNNGVQ 125
               :|...||.        |.:|.:.....|.|.          :.|..|:..|.
Mouse    75 FYTLRKFPVPFQKENVTATLVELGRTAFNQDSFL----------LRVVKIYMKVK---------- 119

  Fly   126 MLMRDKSIRFDMIMVEASHL----DALYGLAEFYNATLL--------GISCMHMTWHIDYLAGNL 178
               ||.|    |::...|||    :.:..|.|.:...||        .|...::|....|....|
Mouse   120 ---RDSS----MLLAGCSHLLHNAEFMASLEESHFDALLTDPFLPCGSIVAQYLTVPTVYFLNKL 177

  Fly   179 ------------APSVYEPISPNGFALDN-TFLSRWSNWIYITEEKLLERLVFRPAQVRLFKKFF 230
                        .|..|.|.|.: |..|. .||.|..|.:....|..:.|:|:.|         :
Mouse   178 PCSLDSEATQCPVPLSYVPKSLS-FNSDRMNFLQRVKNVLLAVSENFMCRVVYSP---------Y 232

  Fly   231 GYPAEKL-------DELRARFSVILVNSHFSMGRVRANVPNIIEVAGVHLSEPPEPCGAELQKYL 288
            |..|.::       .:|.:..|:.|:.|.|.....|..:||::.:.|::..: .:|...|.:.|:
Mouse   233 GSLATEILQKEVTVQDLLSPASIWLMRSDFVKDYPRPIMPNMVFIGGINCLQ-KKPLSQEFEAYV 296

  Fly   289 D-EAEHGAIYFSMGQDILIKYLPENMQKQLLLVFLQMKQRVIWKSELSMLANKSENIYVMDKVPQ 352
            : ..|||.:.||:|.  ::..:||....::.....::.|.|:|:...:..:|.::|..::..:||
Mouse   297 NASGEHGIVVFSLGS--MVSEIPEKKAMEIAEALGRIPQTVLWRYTGTRPSNLAKNTILVKWLPQ 359

  Fly   353 RMVLAHPNLRLFITHGGLQSVMEAIDNGVPMLGLPLFFDQFNNIHRVQLAGMAKVLDPNDLNADT 417
            ..:|.||..|.||||.|...:.|.|.|||||:.:|||.||.:|..|::..|....|:..::.||.
Mouse   360 NDLLGHPKTRAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADD 424

  Fly   418 LIETIKELLENPSYAQRAKEMAASFRDRPMSPLDTAIWWTEYALRNRDTSHMRLNVEEIPLMRYY 482
            |...:|.::.|.||.:....:::..:|||:.|||.|::|.||.:|::...|:|....::...:|:
Mouse   425 LENALKTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYH 489

  Fly   483 RLDSILTFGVRLGCVCGSLIFL 504
            .||.|   |..|..|. :::|:
Mouse   490 SLDVI---GFLLAIVL-TVVFI 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303B2	NP_651154.1	Glycosyltransferase_GTB-type	24..464	CDD:471961	126/488 (26%)
Ugt1a1	NP_964007.2	UDPGT	30..526	CDD:278624	135/524 (26%)