DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt303B2 and ugt-39

DIOPT Version :9

Sequence 1:	NP_651154.1	Gene:	Ugt303B2 / 42776	FlyBaseID:	FBgn0039087	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	NP_504816.2	Gene:	ugt-39 / 3564933	WormBaseID:	WBGene00017329	Length:	523	Species:	Caenorhabditis elegans

Alignment Length:	522	Identity:	117/522 - (22%)
Similarity:	204/522 - (39%)	Gaps:	93/522 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 LYLELGQAA--NILGVFPYRIPSPFQMVRPLIKALVERGHKVTMVTP--------ADYPAKIDGV 72
            |:|..|..:  |.|...|....|..:....:..:|.:.||.||..||        ..|......|
Worm     7 LFLFFGNVSSFNFLVFCPLFAHSHSKFFATIADSLTDAGHNVTFFTPTIVEKYRNVSYTKSTKDV 71

  Fly    73 RHIRVPMLNQLMQNLMKNDQFFDALGDK---------WREG------VLVSTIF---YNVSHAIL 119
            .|             ||..:.....|::         |.|.      :.|..||   ||....::
Worm    72 VH-------------MKPSKKLKEYGEQMSTGDFVRYWTEDSTATEIIPVVRIFQKMYNEQGTVM 123

  Fly   120 NNNGVQMLMRDKSIRFDMIMVEASHLDALYGLAEFYN--ATLLGISCMHMTWHIDYLAGNLAPSV 182
            .:| |.:|...|..:||:|:.|| ::.:.|.|.::..  ..:..:|..|.|        :||..:
Worm   124 KDN-VGILNELKKRKFDVIIFEA-YIYSAYPLMDYLEIPTFIPSVSVAHDT--------SLAIEI 178

  Fly   183 YEPISPNGFALDNTFLSRWSNWIYITEEKLLERLVFRPAQVRLFKKFFGYPAEK----------L 237
            .||:.|   ::.:..||.:.:.:.|||.      .|....|..|....|||..:          :
Worm   179 GEPVMP---SVVSDCLSPFGDKLSITER------AFNAFMVPYFDFMIGYPTHRSFKPPYNPIDI 234

  Fly   238 DELRARFSVILVNSHFSMGRVRANVPNIIEVAGVHL------SEPPEPCGAELQKYLDE---AEH 293
            ..:....|.:.:||:..:...|..:...|::.|:.:      |:..:...:|:.|..::   ...
Worm   235 RSIVPEASFVFLNSNPFVDFPRPTLTKTIQIGGISVDSNELRSQKLDETWSEILKLREKTMLVSF 299

  Fly   294 GAIYFSMGQDILIKYLPEN-MQKQLLLVFLQMKQRVIWKSE---LSMLANKSENIYVMDKVPQRM 354
            |::.:|.......|...:| |:|...:.|       |||.|   ....|...|||:....|||..
Worm   300 GSMLYSKDMPFKNKIALKNAMEKFKNVTF-------IWKYEDDSSDEFAKGIENIHFAKWVPQTA 357

  Fly   355 VLAHPNLRLFITHGGLQSVMEAIDNGVPMLGLPLFFDQFNNIHRVQLAGMAKVLDPNDL-NADTL 418
            :||...|..|:||.||.|:.|....|.|.:..|..|||..|...:.....:..|...|| :::.:
Worm   358 LLADSRLSAFLTHAGLGSINELSYLGKPAILCPQLFDQMRNAKMLVRHNGSIELSKYDLGDSEKI 422

  Fly   419 IETIKELLENPSYAQRAKEMAASFRDRPMSPLDTAIWWTEYALRNRDTSHMRLNVEEIPLMRYYR 483
            :...:.:|.:.|||:.|.::|....::|:.|.:..:...|:|.|......:.....::..:.|:.
Worm   423 VNAFQAILFDSSYAKNALKLAEQLENQPIKPKEMMVKHAEFAARFGRLPSLDPYSRKMTFIEYFL 487

  Fly   484 LD 485
            :|
Worm   488 ID 489

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303B2	NP_651154.1	egt	24..464	CDD:223071	112/493 (23%)
ugt-39	NP_504816.2	Glycosyltransferase_GTB_type	12..503	CDD:299143	115/517 (22%)
ugt-39	NP_504816.2	UDPGT	29..521	CDD:278624	111/500 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.900