Protein Alignment Ugt303B2 and Ugt1a8

DIOPT Version :10

• Sequence 1: NP_651154.1
• Gene: Ugt303B2 / 42776
• FlyBaseID: FBgn0039087
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: NP_787040.2
• Gene: Ugt1a8 / 301595
• RGDID: 708474
• Length: 530
• Species: Rattus norvegicus
• Alignment Length: 523
• Identity: 134/523 - (25%)
• Similarity: 240/523 - (45%)
• Gaps: 69/523 - (13%)

  Fly    18 LYLELG--QAANILGVFPYRIPSPFQMVRPLIKALVERGHKVTMVTP---------ADYPAKIDG 71
            |:|..|  ||..:| |.|......|.| :.:::.|..|||:|.:|.|         .::..|...
  Rat    16 LFLASGFAQAGRLL-VVPMDGSHWFTM-QMIVEKLSHRGHEVVVVIPEVSWHMGKSLNFTVKTYS 78

  Fly    72 VRHIRVPMLNQLMQNLMKNDQFFDALGDKWREGVLVSTI------FYNV--SHAILNNNGVQMLM 128
            |.:        .:::|..:.:||.....|.:|..:.|.:      |:.:  ||.       :.|.
  Rat    79 VSY--------TLEDLNYHFKFFAHNQWKTQEVGMFSLLKHSGKGFFELLFSHC-------RSLF 128

  Fly   129 RDKSI-------RFDMIMVEASHLDALYGLAEFYNATLL----GISCMHMTWHIDYLAGNLAPSV 182
            :||.:       .||.:.::...:..|. ||::::...:    ||.| |   ::|..|...:|..
  Rat   129 KDKKLVEYLKQSSFDAVFLDPFDVCGLI-LAKYFSLPSVVFSGGIFC-H---YLDEGAQCPSPPS 188

  Fly   183 YEPISPNGFALDNTFLSR-WSNWIYITEEKLLERLVFRPAQVRLFKKFFGYPAEKLDELRARFSV 246
            |.|...:.|....||..| |::..|:.|.....  .|....|.:..:....|....| |.:..|:
  Rat   189 YVPRILSKFTDTMTFKERVWNHLSYMKERAFCP--YFFKTAVEIASEVLQTPVTMRD-LFSPVSI 250

  Fly   247 ILVNSHFSMGRVRANVPNIIEVAGVHLSEPPEPCGAELQKYLD-EAEHGAIYFSMGQDILIKYLP 310
            .:..:.|.:...|..:||::.:.|::..: .:|...|.:.|:: ..|||.:.||:|.  ::..:|
  Rat   251 WMFRTDFVLEFPRPVMPNMVYIGGINCHQ-GKPLSKEFEAYVNASGEHGIVVFSLGS--MVSEIP 312

  Fly   311 ENMQKQLLLVFLQMKQRVIWKSELSMLANKSENIYVMDKVPQRMVLAHPNLRLFITHGGLQSVME 375
            |....::.....::.|.|:|:...:..:|.::|..::..:||..:|.||..|.||||.|...:.|
  Rat   313 EKKAMEIAEALGRIPQTVLWRYTGTRPSNLAKNTILVKWLPQNDLLGHPKARAFITHSGSHGIYE 377

  Fly   376 AIDNGVPMLGLPLFFDQFNNIHRVQLAGMAKVLDPNDLNADTLIETIKELLENPSYAQRAKEMAA 440
            .|.|||||:.:|||.||.:|..|::..|....|:..::.||.|...:|.::.|.||.:....:::
  Rat   378 GICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSYKENIMRLSS 442

  Fly   441 SFRDRPMSPLDTAIWWTEYALRNRDTSHMRLNVEEIPLMRYYRLDSI---------LTFGVRLGC 496
            ..:|||:.|||.|::|.||.:|::...|:|....::...:|:.||.|         :.|.|...|
  Rat   443 LHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAIVLTVVFIVYKSC 507

  Fly   497 VCG 499
            ..|
  Rat   508 AYG 510

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303B2	NP_651154.1	Glycosyltransferase_GTB-type	24..464	CDD:471961	121/469 (26%)
Ugt1a8	NP_787040.2	UDPGT	26..521	CDD:278624	129/513 (25%)