Protein Alignment Ugt303B2 and Ugt2a3

DIOPT Version :10

• Sequence 1: NP_651154.1
• Gene: Ugt303B2 / 42776
• FlyBaseID: FBgn0039087
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: NP_001129341.1
• Gene: Ugt2a3 / 289533
• RGDID: 1308444
• Length: 534
• Species: Rattus norvegicus
• Alignment Length: 533
• Identity: 134/533 - (25%)
• Similarity: 250/533 - (46%)
• Gaps: 79/533 - (14%)

  Fly     7 WLAFGLLLHLNLYLELGQAANILGVFPYRIPSPFQMVRPLIKALVERGHKVTMVTPADYP----- 66
            |.....||.| .:...|..:.:| |:|..: |.:..::.:::.|..|||:||::   .||
  Rat     6 WAVAIFLLQL-CWSGCGICSKVL-VWPCDM-SHWLNLKTILEELAARGHEVTVL---KYPSIIID 64

  Fly    67 -AKIDGVRHIRVPM----------LNQLMQ---NLMKNDQFFDA---LGDKWREGVLVSTIFYNV 114
             :|:..::...:|:          ||:::.   |::.|...::|   |.|.:.:   ::..|.::
  Rat    65 QSKLTPLQFENIPVLYETEVAENHLNEIVNLAVNVIPNLSLWEAARTLQDFFLQ---LTGNFEDL 126

  Fly   115 SHAILNNNGVQMLMRDKSIRFDMIMVEASHLDALYGLAEFYNATLLGISCMH-----MTWHIDYL 174
            ..:.|.|..:...:||  .::|:::     ||.:....|.. |.:|.|..::     |.:.::..
  Rat   127 CRSTLYNQTLMNKLRD--AKYDVMV-----LDPVIPCGELV-AEVLQIPFVNTLRFSMGYSMEKY 183

  Fly   175 AGNL-APSVYEPISPNGFALDNTFLSRWSN---------WI----YITEEKLLERLVFRPAQVRL 225
            .|.| .|..|.|:.........||..|..|         |:    :...::...:.:.||.   .
  Rat   184 CGQLPVPLSYVPVVMGELTDHMTFTERVKNMMLSLFFEFWLQQYDFAFWDQFYSKTLGRPT---T 245

  Fly   226 FKKFFGYPAEKLDELRARFSVILVNSHFSMGRVRANVPNIIEVAGVHLSEPPEPCGAELQKYLDE 290
            |.|..|           :..:.|:.:::.:...|..:||...|.|:| .:|.:|...||::::..
  Rat   246 FCKTVG-----------KAEIWLIRTYWDIEFPRPYLPNFEFVGGLH-CKPAKPLPKELEEFVQS 298

  Fly   291 A-EHGAIYFSMGQDILIKYLPENMQKQLLLVFLQMKQRVIWKSELSMLANKSENIYVMDKVPQRM 354
            : |||.:.||:|.  :||.|.|.....:.....|:.|:|:|:......|....|..:::.:||..
  Rat   299 SGEHGVVVFSLGS--MIKNLTEEKANLIASALAQIPQKVLWRYSGKKPATLGPNTRILNWIPQND 361

  Fly   355 VLAHPNLRLFITHGGLQSVMEAIDNGVPMLGLPLFFDQFNNIHRVQLAGMAKVLDPNDLNADTLI 419
            :|.||..|.||||||...:.|||.:||||:|:|:|.||..||..::..|.|..:..|.:.:..|:
  Rat   362 LLGHPKTRAFITHGGTNGIYEAIYHGVPMVGIPMFGDQPYNIAHMEAKGAAVKVAINTMTSADLL 426

  Fly   420 ETIKELLENPSYAQRAKEMAASFRDRPMSPLDTAIWWTEYALRNRDTSHMRLNVEEIPLMRYYRL 484
            ..::.::..|||.:.|..::....|:|:.|||.|::|.|:.:|::...|:|:...::...:|:.|
  Rat   427 SALRAVINEPSYKENAMRLSRVHHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAHDLSWFQYHSL 491

  Fly   485 DSILTFGVRLGCV 497
            |.|   |..|.||
  Rat   492 DVI---GFLLVCV 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303B2	NP_651154.1	Glycosyltransferase_GTB-type	24..464	CDD:471961	119/481 (25%)
Ugt2a3	NP_001129341.1	UDPGT	25..519	CDD:278624	129/513 (25%)