DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt303B2 and ugt-56

DIOPT Version :9

Sequence 1:	NP_651154.1	Gene:	Ugt303B2 / 42776	FlyBaseID:	FBgn0039087	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	NP_506074.2	Gene:	ugt-56 / 188073	WormBaseID:	WBGene00011453	Length:	524	Species:	Caenorhabditis elegans

Alignment Length:	495	Identity:	108/495 - (21%)
Similarity:	191/495 - (38%)	Gaps:	90/495 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 GQAANILGVFPYRIPSPFQMVRPLIKALVERGHKVTMVTPA---DYPAKIDGVRH--IRV---PM 79
            |.|.:||...|..:.|.......:...|..||||||::...   |...::....|  |.|   |.
Worm    16 GSAFDILIYAPRMMQSHVYFTARIANVLAARGHKVTVIDNVFRYDVDNELSSDIHEIISVEPSPE 80

  Fly    80 LNQLMQ-----NLMKNDQ--------FFDALGDKWREGVLVSTIFYNVSHAILNNNGVQMLMRDK 131
            :.:|:.     .::.|.:        ..:.||...|         ...:|.|.|:..:..|   :
Worm    81 VTKLLNTGSLPTILWNSKASPEEQRTIMEGLGHVHR---------LQCTHLIENSTLIPKL---Q 133

  Fly   132 SIRFDMIMVEASHLDALYGLAEFYNATLLGISCMHMTWHIDYLAGNLAPSVYEPISPNGFALDNT 196
            .|:||.         |::.:.:.....:|.:..:..|    .:..:..|....||:   ..:.:|
Worm   134 EIKFDF---------AIHEVFDSCGVGILEVIGVQKT----VIVSSTGPMDVVPIT---LGISDT 182

  Fly   197 -----FLSRWSNWIYITEEK-----LLERLVFRPAQ----VRLFKKFFGYPAEKLDELRARFSVI 247
                 .||.:.:::...|::     |...|.|...|    ..||||::|. .:...|:..:.:::
Worm   183 LNTPSLLSDYGSYLSFFEKRRNLKFLSGMLNFHEMQDSMISPLFKKYYGL-KKPTGEIMRQANLL 246

  Fly   248 LVNSHFSMGRVRANVPNIIEVAGVHLSEPPEPCGAELQKYLDEAEHGAIYFSMGQDILIKYLPEN 312
            ..|.|.....:|.......::.|:...: .:....|.|..|.: ....:..|.|......::|:|
Worm   247 FYNIHEGSDGMRMRGRRSFDIGGIAFKD-QKNLTMEYQTLLSD-PRPKVLVSFGTAATSSHMPQN 309

  Fly   313 MQKQLLLVFLQMKQRV-IWKSELSMLANKSE----NIYVMDKVPQRMVLAHPNLRLFITHGGLQS 372
            ::..|:....||...: |||.|:.....|.|    ||.....:||..:||...:.||:||.|..|
Worm   310 LKNSLMTAMKQMNNVLFIWKYEMEDNFTKQEELTTNIIFKKFLPQTDLLASSKIDLFVTHCGQNS 374

  Fly   373 VMEAIDNGVPMLGLPLFFDQFNNIHRVQLAGMAKVLDPNDLNADT-LIETIKELLENPSYAQRAK 436
            ::||.::||.:|.:|||.||..|.......|:.::|..:|:.... :::.:|..||
Worm   375 LLEAFNSGVRVLAVPLFGDQHRNAKLAFENGLIEILPKSDIETPAKIVKAVKTGLE--------- 430

  Fly   437 EMAASFRDRPMSPLDTAIWWTEYALRNRDTSHMRLNVEEI 476
                     |.:.||..|......|||...:...|.:..|
Worm   431 ---------PNAKLDQNIVLISSLLRNSKENAENLLISTI 461

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303B2	NP_651154.1	egt	24..464	CDD:223071	104/480 (22%)
ugt-56	NP_506074.2	Glycosyltransferase_GTB_type	<216..>399	CDD:299143	50/185 (27%)
ugt-56	NP_506074.2	Glycosyltransferase_GTB_type	<353..453	CDD:299143	34/117 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.900