DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt303B2 and ugt-55

DIOPT Version :9

Sequence 1:	NP_651154.1	Gene:	Ugt303B2 / 42776	FlyBaseID:	FBgn0039087	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	NP_506073.2	Gene:	ugt-55 / 188072	WormBaseID:	WBGene00011452	Length:	512	Species:	Caenorhabditis elegans

Alignment Length:	521	Identity:	119/521 - (22%)
Similarity:	206/521 - (39%)	Gaps:	90/521 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 LYLELGQ---AANILGVFPYRIPSPFQMVRPLIKALVERGHKVTM---VTPADYPAKIDGVRHIR 76
            ::|..|.   :..||...|..|||....|..:...|.:|||.|.:   |..:|...|:| ::.|.
Worm    12 IFLNYGTPCLSLRILVYSPRMIPSHVAFVANIANLLGQRGHNVVVVDNVLRSDISNKLD-LKVIE 75

  Fly    77 VPMLNQLMQNLMKNDQFFDALGDKWREGVLVSTIFYNVSH------AILNNNGVQMLMRDKSI-- 133
            ..:..:...|:.|      .|.|:     .:...|:::.:      .::...|:..|.:.|.:
Worm    76 KVVKVETSANVAK------LLADQ-----SIPINFWSMRNEPEEQKKVMKQLGIIFLEQCKYLVS 129

  Fly   134 RFDMIMVEASHLDALYGLAEFYNATLLGI-SCMHMTWHIDYLAGNLAPSVYEPISPNGFALDNTF 197
            :.:.:..|..||:..:|:.|.::...:|| ..:.:...:...:..:...|.|.:..:....|.:.
Worm   130 KEETVFNELKHLEFDFGIHEVFDICGIGIFEKLGIRKSVILSSTGMRDIVNEALGISSQLQDASI 194

  Fly   198 LSRWSNWI--YITEEKLLERLVFRPAQVRLFKKFFGYPAEKLDEL---------RARFS-VILVN 250
            ||.:.|.|  |    .:...|.|..|    ::.||...::.|:.|         ..||| ::.:|
Worm   195 LSDYGNSIPFY----GIRRNLKFHSA----WRNFFEVQSKTLEPLFETTSSFENLLRFSNLMFLN 251

  Fly   251 SHFSMGRVRANVPNIIEVAGVHLSEPPEPCGAE----LQKYLDEAEHGAIYFSMGQDILIKYLPE 311
            :|......|.....:.|:.|:.. :.|.|...|    ..||     :..|..|.|.......:||
Worm   252 THELADAHRPWSRRVHEIGGISF-KFPMPLKNEYINLFNKY-----NSIILVSFGTTTPSFLMPE 310

  Fly   312 NMQKQLLLVFLQMKQRV-IWKSELS---MLANKSENIYVMDKVPQRMVLAHPNLRLFITHGGLQS 372
            ..:..|:..|.:....: |||.|..   ...||..|:.....:||..:|....::|||||||..|
Worm   311 KYKNTLINTFQRFPDFLFIWKYEKDDEFTQKNKKGNVVFKKFLPQVDLLESRKIKLFITHGGQNS 375

  Fly   373 VMEAIDNGVPMLGLPLFFDQFNNIHRVQLAGMAKVLDPNDL-NADTLIETIKE-----------L 425
            ::|...:....|..|||.||..|.......|::.||..:.| |.:.:...||:           |
Worm   376 LLETFHSNTRTLITPLFGDQHRNAQIALENGLSHVLLKDQLANEELVYAAIKQGTESNKKLDDNL 440

  Fly   426 LENPSYAQRAKEMAASFRDRPMSPLDTAIWWTEYALRNRDTSHMR-LNVEEIPLMRYYRLDSILT 489
            |:..|..:.||:.:.:..      |||        :.:..|.::. ||.|..|  :.|..|.||.
Worm   441 LKLSSNLKNAKQTSENLF------LDT--------VESTYTDNLSPLNFEFYP--KLYSSDQILL 489

  Fly   490 F 490
            :
Worm   490 Y 490

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303B2	NP_651154.1	egt	24..464	CDD:223071	108/486 (22%)
ugt-55	NP_506073.2	UDPGT	35..>399	CDD:278624	87/389 (22%)
ugt-55	NP_506073.2	Glycosyltransferase_GTB_type	<247..>399	CDD:299143	42/157 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.900