DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt303B2 and ugt-38

DIOPT Version :9

Sequence 1:	NP_651154.1	Gene:	Ugt303B2 / 42776	FlyBaseID:	FBgn0039087	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	NP_504812.1	Gene:	ugt-38 / 184294	WormBaseID:	WBGene00017333	Length:	523	Species:	Caenorhabditis elegans

Alignment Length:	548	Identity:	126/548 - (22%)
Similarity:	213/548 - (38%)	Gaps:	90/548 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 LLLHLNLYLELGQAANILGVFPYRIPSPFQMVRPLIKALVERGHKVTMVTPA--------DYPAK 68
            |.|...||..: .:.|.|...|....|..:....:..:|.:.||.|...||.        :|...
Worm     4 LALLFTLYANV-SSFNFLVFCPLFAHSHSKFFATIADSLTDAGHNVAFFTPIIVEKYRNFNYTKS 67

  Fly    69 IDGVRHIRVPMLNQLMQNLMKNDQFFDALGDKWREG------VLVSTIF---YNVSHAILNNNGV 124
            ...|.::......:.....|....|.    ..|.|.      :.|..||   ||....::.:| :
Worm    68 TKDVVYMEPSKKLKEYGRQMSTGDFV----RYWTEDSTATEIITVVRIFQKMYNEQGTVMKDN-I 127

  Fly   125 QMLMRDKSIRFDMIMVEASHLDALYGLAEFYN--ATLLGISCMHMTWHIDYLAGNLAPSVYEPIS 187
            ::|...|..:||:|:.||....| |.|.::..  ..:..:|..|.|        .||..:.||:.
Worm   128 EILNDLKKRKFDVIIFEAFIFSA-YPLMDYLEIPTFIPSLSVAHDT--------ALAVEIGEPVM 183

  Fly   188 PNGFALDNTFLSRWSNWIYITEEKLLERLVFRPAQVRLFKKFFGYPAEK----------LDELRA 242
            |   ::.:..||.:.:.:.|||.      .|....|..|....|||..:          :..:..
Worm   184 P---SVVSDCLSPFGDKLSITER------AFNAFMVPYFDFMIGYPTHRSFKPPYNPIDIRSIVP 239

  Fly   243 RFSVILVNSHFSMGRVRANVPNIIEVAGVHL------SEPPEPCGAELQKYLDE---AEHGAIYF 298
            ..|.:.:||:..:...|..:...|::.|:.:      |:..:...:|:.|..::   ...|::.:
Worm   240 EASFVFLNSNPFVDFPRPTLTKTIQIGGISVDSNELRSQKLDETWSEILKLREKTMLVSFGSMLY 304

  Fly   299 SMGQDILIKYLPEN-MQKQLLLVFLQMKQRVIWKSE---LSMLANKSENIYVMDKVPQRMVLAHP 359
            |.......|...:| |:|...:.|       |||.|   ....|...|||:....|||..:||..
Worm   305 SKDMPFKNKIALKNAMEKFKNVTF-------IWKYEDDSSDEFAKGIENIHFAKWVPQTALLADS 362

  Fly   360 NLRLFITHGGLQSVMEAIDNGVPMLGLPLFFDQFNNIHRVQLAGMAKVLDPNDL-NADTLIETIK 423
            .|..|:||.||.|:.|....|.|.:..|..|||..|...:.....:..|...|| .::.:||..:
Worm   363 RLSAFLTHAGLGSITELSYLGKPAILCPQLFDQMRNTKMLVRHNGSIELSKYDLGKSEKIIEAFQ 427

  Fly   424 ELLENPSYAQRAKEMAASFRDRPMSPLDTAIWWTEYALRNRDTSHMRLNVEEIPLMRYYRLD--- 485
            .:|.:.|||:.|:::|....::|:.|.:..:...|||.|......:.....::..:.|:.||
Worm   428 AILFDSSYAKNAQKLAEQLENQPIKPKEMMVKHAEYAARFGRLPSLDPYSRKMSFVEYFLLDVAA 492

  Fly   486 ---SILTFGVRLGCVCGSLIFLGWRLYQ 510
               .||||          ::|:..:|.|
Worm   493 ICVFILTF----------VVFVVTKLVQ 510

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303B2	NP_651154.1	egt	24..464	CDD:223071	112/482 (23%)
ugt-38	NP_504812.1	Glycosyltransferase_GTB_type	12..512	CDD:299143	122/540 (23%)
ugt-38	NP_504812.1	UDPGT	29..521	CDD:278624	119/522 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.900