DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt303B2 and ugt-7

DIOPT Version :9

Sequence 1:	NP_651154.1	Gene:	Ugt303B2 / 42776	FlyBaseID:	FBgn0039087	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	NP_504343.2	Gene:	ugt-7 / 182577	WormBaseID:	WBGene00015739	Length:	530	Species:	Caenorhabditis elegans

Alignment Length:	568	Identity:	124/568 - (21%)
Similarity:	229/568 - (40%)	Gaps:	123/568 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 LLHLNLYLELGQAANILGVFPYRIPSPFQMVRPLIKALVERGHKVTM----VTPADYPAKIDGVR 73
            |:.|..:|:...|...|.:.|....|..:.:..:...|.:.||:|.:    :..|....|:  ::
Worm     3 LVFLTFFLQYSYAFKYLIISPIYSYSHVKFMSNIADTLADHGHEVVVFQQQIVEALRDKKV--IK 65

  Fly    74 HIRVPMLN--------QLMQNLMKN-----------------DQFFDALGDKWREGVLVSTIFYN 113
            :..:.::|        :..:|..|:                 |||.:|:..             :
Worm    66 NPDIKIINYEANTAGKEFYRNRPKSSVTKYWTTNQAANPSAADQFAEAMSK-------------D 117

  Fly   114 VSHAILNNNGVQMLMRDKSIRFDMIMVEASHLDALYGLAEFYNATLLGISCMHMTWHIDYL---- 174
            :.|..|      .:..|||:.   .|:::.|.|.|  |||.::...|.:.        |||
Worm   118 LEHMCL------QVFEDKSLH---TMLKSEHFDVL--LAEPFDPCGLYLG--------DYLKIPS 163

  Fly   175 -AGNLAPSVYEPI-----SPNG----------FALDNTFLSRWSN-WIYITEEK--------LLE 214
             ...:|.|..:|:     .|:|          :..::....|.:| |::....:        ||:
Worm   164 TIVAMASSRIDPVQWALGQPSGLNFIPGPDSKYGEESGVWDRINNVWMFFMRTRMFRAVYWNLLD 228

  Fly   215 RLVFRPAQVRLFKKFFGYPAEKLDELRARFSVILVNSHFSMGRVRANVPNIIEVAGVHLSEP--- 276
            :|.|:.          |.....:||:.|..:.:..||:..:.....::...:.:.|..::..
Worm   229 KLRFKT----------GLEIRNIDEIVAESAYLFYNSNPYLDFPFPSLTKCVPIGGFSMNTTNWK 283

  Fly   277 ----PEPCGAELQKYLDEAEHGAIYFSMGQDILIKYLPENMQKQLLLVFLQMKQ-RVIWKSE--- 333
                ||.....|||     ....::.|.|..|....:|:..:..::.|...|.. ..|||.|
Worm   284 SENLPENLKNILQK-----RPNTVFISFGSVIRSADMPQEYKNAIIEVTKLMSDVTFIWKYEDEK 343

  Fly   334 -LSMLANKSENIYVMDKVPQRMVLAHPNLRLFITHGGLQSVMEAIDNGVPMLGLPLFFDQFNNIH 397
             ..|..|..||:::|..:||..:||...:.||||||||.|:||...:|.|.:.:||||||..|..
Worm   344 DEEMRGNIPENVHLMKWLPQPALLADSRVSLFITHGGLGSIMEVAYSGKPAIVIPLFFDQPMNGE 408

  Fly   398 RVQLAGMAKVLDPNDL-NADTLIETIKELLENPSYAQRAKEMAASFRDRPMSPLDTAIWWTEYAL 461
            .::..|.|:|....:| ||..|.:.|:.:::||.|...||:::...:.:|::|::..:...|:|.
Worm   409 MLRRHGGAEVYSKFELSNAKKLKKVIQNMIQNPKYLANAKKLSNLLQKQPINPIERLVKHAEFAA 473

  Fly   462 RNRDTSHMRLNVEEIPLMRYYRLDSILTFGVRLGCVCGSLIFLGWRLY 509
            ..:....:......:...:::.||.:.|.   |.....|.:|:.|..|
Worm   474 EFKKLPELDPYSRHLNFFQFFFLDIVATL---LILFMLSALFVYWITY 518

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303B2	NP_651154.1	egt	24..464	CDD:223071	113/510 (22%)
ugt-7	NP_504343.2	egt	1..477	CDD:223071	116/522 (22%)
ugt-7	NP_504343.2	UDPGT	27..521	CDD:278624	118/544 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.810