DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt303B2 and ugt-5

DIOPT Version :9

Sequence 1:	NP_651154.1	Gene:	Ugt303B2 / 42776	FlyBaseID:	FBgn0039087	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	NP_506200.1	Gene:	ugt-5 / 179753	WormBaseID:	WBGene00013906	Length:	534	Species:	Caenorhabditis elegans

Alignment Length:	561	Identity:	123/561 - (21%)
Similarity:	222/561 - (39%)	Gaps:	101/561 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MRLGYAWLAFGLLLHLNLYLELGQAANILGVFPYRIPSPFQMVRPLIKALVERGHKVTMVTP--- 62
            |.:.:.:|.|.||...|:     .:.|.|.:.|....|..:.:..:...|.:.||:||...|
Worm     1 MNIHHVFLIFVLLFIKNV-----ASYNFLVISPVYGFSHMKSMAIIANQLADAGHQVTYFQPFVV 60

  Fly    63 ---ADYPAKIDGVRHIRVPMLNQLM-QNLMKNDQFFDALGDKWREGVLVSTI------------- 110
               .|:    |.:::..:.::|... :...||......|.|.|......|.:
Worm    61 ELFKDH----DLIKNPNIEIMNYFHDEEGKKNIPGHSVLSDAWTSYKYQSDVGQKIFAPRILHQS 121

  Fly   111 FYNVSHAILNNNGVQMLMRDKSIRFDMIMVEASHLDALYGLAEFYNATLLGISCMHMTWHIDYLA 175
            |..:...:..:..:...::||  :||:::.|......|| ||::          :.|...|....
Worm   122 FQEMCRHMFEDEALHRQLKDK--KFDVVLSETFDFCGLY-LADY----------LEMPAIISVFT 173

  Fly   176 GNLAPSV-----------YEPISPNGFALDNTFLSRWSN-WIYITEEKLLERLVFRPAQVRLFKK 228
            ||...::           |.|...:.|..:.:...|::| |     .|:|....|.    .||.:
Worm   174 GNRLNAITNALGEPSFLHYLPSPSSSFNANMSLYDRFNNFW-----HKILSSSTFG----ELFDR 229

  Fly   229 FFGYPAEKLDELRARFSVILVNS---HFS-----MGRVRANVPNIIEVAGVHLSEPPEPCGAELQ 285
            .:. ...:|...:||....::|.   |||     :..|...:..:|.:.|..:.....|   .:.
Worm   230 QYA-DVYRLTNGKARHWKQILNDVTYHFSNSNPYLDFVIPTIAKVIPIGGYTMDYKQVP---PVS 290

  Fly   286 KYLD---EAEHGAIYFSMGQDILIKYLPENMQKQLLLVFLQMKQRV--IWK----SELSMLANKS 341
            |.||   ......::.|.|..|..||:|:. .||.::.|.:..:.|  :||    .|..:..|..
Worm   291 KDLDTILNLRSSTVFISYGTMISAKYMPDE-YKQSMIDFFKDNKNVTFLWKYEEPEEKFIKENIP 354

  Fly   342 ENIYVMDKVPQRMVLAHPNLRLFITHGGLQSVMEAIDNGVPMLGLPLFFDQFNNIHRVQLAGMAK 406
            :|:::....||:.:||...::||||||||.|.||...:..|.:..|||.||.:|...::..|..:
Worm   355 DNVHLSTWFPQQSLLADKRVKLFITHGGLGSTMELAYSAKPAIVTPLFADQPSNAQMLERHGSVE 419

  Fly   407 VLDPNDL-NADTLIETIKELLENPSYAQRAKEMAASFRDRPMSPLDTAIWWTEYALRNRDTSHMR 470
            ||..:|: |.....:.:|.:|.:..|.:.|..:|....::|:||.:..:...|.|.|......:.
Worm   420 VLSKHDIPNWKKQSDLLKTMLADKKYQEAATRLADILNNQPISPRELMLKHAENAARFGKIPSLT 484

  Fly   471 LNVEEIPLMRYYRLDSIL---------------TFGVRLGC 496
            ...:::..:.:|.:|.|:               .||:...|
Worm   485 PFAKDMGFIEFYNIDLIIYSVSFTLFAIYVTIEIFGIVKNC 525

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303B2	NP_651154.1	egt	24..464	CDD:223071	111/489 (23%)
ugt-5	NP_506200.1	egt	6..509	CDD:223071	119/538 (22%)
ugt-5	NP_506200.1	UDPGT	32..527	CDD:278624	114/525 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.810