DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt303B2 and ugt-33

DIOPT Version :9

Sequence 1:	NP_651154.1	Gene:	Ugt303B2 / 42776	FlyBaseID:	FBgn0039087	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	NP_505692.2	Gene:	ugt-33 / 179464	WormBaseID:	WBGene00007946	Length:	522	Species:	Caenorhabditis elegans

Alignment Length:	542	Identity:	116/542 - (21%)
Similarity:	196/542 - (36%)	Gaps:	104/542 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 QAANILGVFPYRIPSPFQMVRPLIKALVERGHKVTMVTP--------ADY-----------PAK- 68
            |..|.|...|....|..:.:..:...|.:.||.||.:.|        ..|           |:|
Worm    17 QPFNYLVFCPLYAHSHHKFLAKIADTLTDAGHNVTFLAPIVLRKYENVKYLESTKDIVYIQPSKE 81

  Fly    69 --------------------IDGVRHIR--VPMLNQLMQNLMKNDQFFDALGDKWREGVLVSTIF 111
                                |..|..:|  |.|..||.::|.|:....|.|
Worm    82 LEALGFTSNYSKFWTEDATAIQFVPAVRTFVKMFVQLYEDLKKDLSVLDEL-------------- 132

  Fly   112 YNVSHAILNNNGVQMLMRDKSIRFDMIMVEASHLDALYGLAEF--YNATLLGISCMHMTWHIDYL 174
                               |:..||.|:.|.. ....:.:||:  ..|.|..:|..|.|....::
Worm   133 -------------------KNRNFDAIVFEFL-CPTAFPIAEYLGIKALLPSLSMTHHTQMSRWI 177

  Fly   175 AGNLAPSVYEPISPNGFALDNTFLSRWSNW---IYITEEKLLERLVFRPAQVRLFKKFFGYPAEK 236
            ....:|:|. |...:.|..|..|..|..|.   ::.|....:.|:.           .|..|..|
Worm   178 GEPSSPTVL-PSMISSFGDDMNFWERLGNTLGDVFFTLFVDMPRMT-----------SFSDPERK 230

  Fly   237 LD--ELRARFSVILVNSHFSMGRVRANVPNIIEVAGVHLSE---PPEPCGAELQKYLDEAEHGAI 296
            :|  |:..|...:.:||:..:...|..:...:.:.|:.::.   ..:....:..|.:.|.:.. |
Worm   231 IDFYEMSVRAPFMFMNSNPYLDYARPILTKTVLIGGISVNVTQLKQKKLNEKYDKIISERQQN-I 294

  Fly   297 YFSMGQDILIKYLPENMQKQLLLVFLQMKQ-RVIWKSELS--MLANKSENIYVMDKVPQRMVLAH 358
            ..|.|..|..|.:|:..:..|:.|...... ..|||.|..  ..|....|::....|||..:||.
Worm   295 LISFGSMIFSKDMPDVYKNTLVQVIKSFPNVTFIWKYEEDDVSFAKHLPNLHFSKWVPQTALLAD 359

  Fly   359 PNLRLFITHGGLQSVMEAIDNGVPMLGLPLFFDQFNNIHRVQLAGMAKVLDPNDLNA-DTLIETI 422
            ..|..|:||.||.||.|....|.|.:.:|||.||..|...:.....:..|...||:: :.|...|
Worm   360 SRLSAFVTHAGLGSVTELSYMGKPAVLIPLFADQLRNSKTLSRHNGSITLSKYDLSSFEKLRFAI 424

  Fly   423 KELLENPSYAQRAKEMAASFRDRPMSPLDTAIWWTEYALRNRDTSHMRLNVEEIPLMRYYRLDSI 487
            ..:|.:..|...|:.::...:|:|:||....:...|:..:..:..::.....::..:.:|.||.|
Worm   425 NTILNDERYKINAEILSQQLQDQPVSPHALLVKHAEFGAKYGELPNLDPCSRQMSFISFYMLDII 489

  Fly   488 LTFG-VRLGCVCGSLIFLGWRL 508
            :..| :.:....|.::.:.|.|
Worm   490 VFVGFILITTTIGIVLTVKWIL 511

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303B2	NP_651154.1	egt	24..464	CDD:223071	108/495 (22%)
ugt-33	NP_505692.2	Glycosyltransferase_GTB_type	1..498	CDD:299143	113/527 (21%)
ugt-33	NP_505692.2	UDPGT	31..520	CDD:278624	112/528 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		otm14625
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.900