DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt303B2 and ugt-51

DIOPT Version :9

Sequence 1:	NP_651154.1	Gene:	Ugt303B2 / 42776	FlyBaseID:	FBgn0039087	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	NP_504388.2	Gene:	ugt-51 / 178905	WormBaseID:	WBGene00015369	Length:	524	Species:	Caenorhabditis elegans

Alignment Length:	546	Identity:	130/546 - (23%)
Similarity:	222/546 - (40%)	Gaps:	100/546 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 AFGLLLHLNLYLELGQAANILGVFPYRIPSPFQMVRPLIKALVERGHKVTMV------------- 60
            |..:|..|.|:|   .||||:........|.......||.:|.|:||.|.:|
Worm     8 ALTILAVLPLFL---NAANIVFFINAIGKSHLDFGDSLIDSLKEKGHTVDLVIARINDLAKGNEN 69

  Fly    61 TPAD-------------------------YPAKIDGVRHIRVPMLNQLMQNLMKNDQFFDALGDK 100
            :.||                         .|..|||.|...: :.|||.:..:.:::....|.:|
Worm    70 SKADRFYTLGFKNGSSWHKLNHLTSPFENNPFPIDGFRQYTL-IGNQLCEIALHDEKLHQFLSEK 133

  Fly   101 WREGVLVSTIFYNVSHAILNNNGVQMLMRDKSIRFDMIMVEASHLDALYGLAEFYNATLLGISCM 165
            ..: |.|.::|......|||..||..:..                         :||..| :|..
Worm   134 SYD-VGVVSVFDYCGIGILNKAGVSSITT-------------------------FNAVPL-MSIQ 171

  Fly   166 HMTWHIDYLAGNLAPSVYEPISPNGFALDNTFLSRWS--NWIYITEEKLLERLVFRPAQVRLFKK 228
            .:|..:..:|..:.|..|.      |.|.......|:  .|.:|...::   ...|..|..||:|
Worm   172 TVTIGLPNIASQVVPLFYT------FDLATLSGKLWNLITWAHINFHQI---PTLRKEQELLFQK 227

  Fly   229 FFGYPAEKLDELRARFSVILVNSHFSMGRVRANVPNIIE-----VAGVHLSEPPEPCGAELQKYL 288
            .:| |:..::|:..:..:..|||:..|     ..|.:|.     :.|::| :.|:|....|...|
Worm   228 VYG-PSFSINEVIDKVDLSFVNSNEIM-----ETPMLINHRIQYIGGINL-KTPKPVDHHLDNLL 285

  Fly   289 DEAEHGAIYFSMGQDILIKYLPENMQKQLLLVFLQMKQ-RVIWKSEL----SMLANKSENIYVMD 348
            .::.:|.|.||.|..|.....|....:..:.||.:..: ..:||..:    ..|...:||:.::|
Worm   286 SKSSNGTIIFSFGTQIPGAVYPRYAVRNFVKVFKKYPEYTFLWKYNVQPGEEKLFEDAENVILLD 350

  Fly   349 KVPQRMVLAHPNLRLFITHGGLQSVMEAIDNGVPMLGLPLFFDQFNNIHRVQLAGMAKVLDPNDL 413
            .:||..:|..|.:..||:|.||.|..||...|.|::.:|||.||.:|.......|...:|:.:.|
Worm   351 WLPQTDLLYDPRVIGFISHVGLNSFNEASYAGKPIIAIPLFADQPHNARNGVARGTTYLLNKSKL 415

  Fly   414 NADTLIETIKELLENPSYAQRAKEMAASFRDRPMSPLDTAIWWTEYALRNRDTSHM-RLNVEEIP 477
            :.:::...::.:|.:.||.:.|:::.....::|..|.|..:.|.|||..|.....: .|...::.
Worm   416 SEESIENGLRAILFDKSYTESARKLQKMLVEKPTKPKDRFVEWMEYAAVNPGLHKIFALPGAKMG 480

  Fly   478 LMRYYRLDSILTFGVRLGCVCGSLIF 503
            .:.||.:|:|:.  :...||..:.||
Worm   481 NIEYYCVDTIVF--IAFSCVTFTYIF 504

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303B2	NP_651154.1	egt	24..464	CDD:223071	115/489 (24%)
ugt-51	NP_504388.2	UDPGT	43..505	CDD:278624	119/508 (23%)
ugt-51	NP_504388.2	egt	<217..496	CDD:223071	75/287 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.810