DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt303B2 and ugt-52

DIOPT Version :9

Sequence 1:	NP_651154.1	Gene:	Ugt303B2 / 42776	FlyBaseID:	FBgn0039087	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	NP_499988.1	Gene:	ugt-52 / 176904	WormBaseID:	WBGene00018931	Length:	541	Species:	Caenorhabditis elegans

Alignment Length:	532	Identity:	123/532 - (23%)
Similarity:	224/532 - (42%)	Gaps:	79/532 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 LHLNLYLELGQAANILGVFPYRIPSPFQMVRPLIKALVERGHKVTMVTPADYPAKIDGVRHIRVP 78
            ||:..|:.|      ||      .|.......||::|||.||.|.::.     |:::.  |::..
Worm    32 LHVLFYILL------LG------KSHIDFTDSLIESLVENGHTVDLII-----ARMNS--HVKSN 77

  Fly    79 MLNQLMQNLMKNDQF-------------FDALGDKWREGVLVSTIFYNVSHAILNNNGVQMLMRD 130
            ..|.:.:......|.             |......|.|......|..::....|::.|:...:
Worm    78 GTNMVTRKYTYGFQEESPWNKAPHLLNPFKGRERTWNEHTYYMDIVTDLCEIGLSDAGLHAFI-- 140

  Fly   131 KSIRFDMIMVEASHLDALYGLAEFYN-ATLLGISCMHMTWHIDYLAG--NLAPSVYEPISPNGFA 192
            .|.::| |.:...:.:....|.::|. .:::.:|.:.:.......||  | :|:|.:.|    |.
Worm   141 SSQKYD-IGIATEYENCGVALMKYYKIPSIVSVSSLPILDRQSLAAGMPN-SPAVTQAI----FE 199

  Fly   193 LDN--TFLSRWS---NWIYITEEKLLERLVFRP----AQVRLFKKFFGYPAEKLD--ELRARFSV 246
            .::  |:..::.   ||.:||       |:..|    .|..:.||..|   |..|  .|.....:
Worm   200 AEDLTTYWGKFRNFLNWAHIT-------LIINPYCEKHQSEVIKKHLG---ENFDTSNLIESLDL 254

  Fly   247 ILVNSHFSMGRVRANVPNIIEVAGVHLSEPPEPCGAELQKYLDEAE--HGAIYFSMGQDILIKYL 309
            ..|||:..:...|.:...|..:.|::|.:..:....|::|.:.:..  :|.:.|..|..:.....
Worm   255 AFVNSNELIETPRVSSHKIKYIGGINLKKSKDRLDEEVEKVITQKPIGNGIVVFCFGTQVPSSLF 319

  Fly   310 PENMQKQLLLVFLQMKQ-RVIWKSEL-----SMLANKSENIYVMDKVPQRMVLAHPNLRLFITHG 368
            |..:::.....|..... ..:||.|:     .:.|| :.|:.::..:||..:|.....:.||:|.
Worm   320 PIEVRRAFAQAFRHFPDFTFVWKYEMQDGDEQIFAN-TTNLRLLKWLPQTDLLNDARTKAFISHV 383

  Fly   369 GLQSVMEAIDNGVPMLGLPLFFDQFNNIHRVQLAGMAKVLDPNDLNADTLIETIKELLENPSYAQ 433
            ||.|.:|:...|||:|.:|||.||.:|.......|...:||...|....:::.::.:|.:.||..
Worm   384 GLNSYLESSYAGVPILAVPLFADQPHNAFSGMSIGTTYMLDKTRLTTPNIVKGLEAVLYDSSYTL 448

  Fly   434 RAKEMAASFRDRPMSPLDTAIWWTEYALRNRDTSHMRLNV--EEIPLMRYYRLDSILTFGVRLGC 496
            .||.::....:||..|....:.|.|:|.|| ...|..||:  :.:.:..||.|| |::|.:.|..
Worm   449 NAKRISKMLHERPNPPKKIFVEWIEFASRN-PLLHRNLNLIGQNMSVFEYYCLD-IISFCILLLS 511

  Fly   497 VCGSLIFL--GW 506
            :..|:.:|  ||
Worm   512 IVISVFYLGTGW 523

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303B2	NP_651154.1	egt	24..464	CDD:223071	104/474 (22%)
ugt-52	NP_499988.1	UDPGT	53..537	CDD:278624	115/499 (23%)
ugt-52	NP_499988.1	Glycosyltransferase_GTB_type	<231..517	CDD:299143	75/291 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.810