DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt303B2 and ugt-62

DIOPT Version :9

Sequence 1:	NP_651154.1	Gene:	Ugt303B2 / 42776	FlyBaseID:	FBgn0039087	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	NP_497918.1	Gene:	ugt-62 / 175591	WormBaseID:	WBGene00010904	Length:	531	Species:	Caenorhabditis elegans

Alignment Length:	535	Identity:	128/535 - (23%)
Similarity:	237/535 - (44%)	Gaps:	67/535 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 LLHLNLYLELGQAANILGVF-PYRIPSPFQMVRPLIKALVERGHKVTMVTPA---DYPAKIDGVR 73
            |:.|.|.|....:|....|| ||...|..|....:.:.|...||.|||:..:   ||...:...:
Worm     3 LIALFLLLLGAVSAYKYAVFVPYMANSQVQFCTRVAEVLANGGHDVTMIHLSHLPDYKTDVKIPK 67

  Fly    74 HIRVPMLNQLMQNLMKNDQFFDALGDKWREGVLVSTIFYNVSHAILN---------NNGVQMLMR 129
            :|:|..:...::.|.|      ||.:|.:...:..........|:::         .:|.:.::|
Worm    68 NIKVHRVEAYVEGLTK------ALLEKEQSAFIFKDTGLKDMPAMMSMFSRFGKMFQDGCRNIVR 126

  Fly   130 DKSIRFDMIMVEASHLDALYGLAEFYNATLLGISCMHM----TW-------HIDYLAGNL-APSV 182
            :|..   |..:|....|..|  :..|::..:|:  :|.    :|       .:|::|..: .|.:
Worm   127 NKEF---MKWLENEKFDVAY--SYIYSSCPIGL--IHAAKIPSWVWLNSGALMDFVAETVGVPII 184

  Fly   183 YEPISPNGFALDNT--FLSRWSNWIYITEEKLLERLVFRPAQVRLFKKFFGYP--AEKLDELRAR 243
            ...:.|.....|:.  |..|..::|..|...:|.|.:....:.::|:.....|  ...:| |.|:
Worm   185 PSYVPPLMMESDDEMGFFFRMKSFIGHTLMTVLHRRMTSNGETQIFRDELNDPNFPHTMD-LGAK 248

  Fly   244 FSVILVNSHFSMGRVRANVPNIIEVAGVHLS-EPPEPCGAELQKYLDEAEHGAIYFSMGQDILIK 307
            ..:::|||:......|..:..::.:.|:.:. :..:|...|.:| :.|...|.|.||.|......
Worm   249 CPLVIVNSNELYDLPRPTLAKVVNIGGLGVGFDSAKPLTGEFKK-ISETGKGMIVFSFGSVAAAH 312

  Fly   308 YLPENMQKQLLLVF-----LQMKQRVIWKSELSMLANKSENIYVMDKVPQRMVLAHPNLRLFITH 367
            .:|...:..:|..|     .|...|.: ..:|:....|  |:::...:||:.:|.|...:.||||
Worm   313 DMPLEWKNSILEAFSSLPDYQFLMRYV-ADDLNDRLPK--NVHLFKWLPQKDLLLHNKTKAFITH 374

  Fly   368 GGLQSVMEAIDNGVPMLGLPLFFDQFNNIHRVQLAGMAKVLDPNDLNADTLIETIKELLENPSYA 432
            ||..|:.|||..|||::.:.||.||..|....:..|.|..:...:::..|:::.|.|::||.||.
Worm   375 GGYNSMQEAISAGVPLVTIALFGDQPKNSKVAKKHGFAVNIQKGEISKKTIVKAIMEIVENDSYK 439

  Fly   433 QRAKEMAASFRDRPMSPLDTAIWWTEY-----ALRNRDTSHMRLNVEEIPLMRYYRLDSILTFGV 492
            |:...::|..|.:||.|.:..:.|:|:     .|.|.:.:..:||     ..:|:.|| ::||
Worm   440 QKVSRLSAMVRAQPMKPAERLLKWSEFLAEFKTLDNLEPAGQKLN-----FFQYHSLD-VITF-- 496

  Fly   493 RLGCVCGSLIFLGWR 507
             |..|...:.::|:|
Worm   497 -LFIVIFIVFYIGYR 510

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303B2	NP_651154.1	egt	24..464	CDD:223071	112/479 (23%)
ugt-62	NP_497918.1	UDPGT	37..520	CDD:278624	117/501 (23%)
ugt-62	NP_497918.1	egt	<251..471	CDD:223071	61/223 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		otm14329
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.810