Protein Alignment Ugt303B2 and UGT3A2

DIOPT Version :9

• Sequence 1: NP_651154.1
• Gene: Ugt303B2 / 42776
• FlyBaseID: FBgn0039087
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: XP_011512290.1
• Gene: UGT3A2 / 167127
• HGNCID: 27266
• Length: 550
• Species: Homo sapiens
• Alignment Length: 569
• Identity: 136/569 - (23%)
• Similarity: 247/569 - (43%)
• Gaps: 110/569 - (19%)

  Fly    22 LGQAANILGVFPYRIPSPFQMVRPLIKALVERGHKVTMVTP---------ADYPAKIDGVRHIRV 77
            |.:||.||.:.... .|.:.::..:.:.|.:.||.|||:..         :|.||...  |:.|:
Human    19 LSEAAKILTISTVG-GSHYLLMDRVSQILQDHGHNVTMLNHKRGPFMPGLSDSPASAS--RYPRI 80

  Fly    78 PMLNQLMQ--------------------------NLMKNDQFF--DALGDKWREGVLVSTIFY-- 112
            ..|.:..|                          ...|:..||  :.||.:.:...|::.:.|
Human    81 LYLQKYCQFGLKDFKKEEKSYQVISWLAPEDHQREFKKSFDFFLEETLGGRGKFENLLNVLEYLA 145

  Fly   113 -NVSHAILNNNGVQMLMRDKSIRFDMIMVEASHLDALYGLAEFYNATLLG---ISCMHMTWHIDY 173
             ..|| .||...:...:::::  |||::||.      :....|..|..||   ::.:..::
Human   146 LQCSH-FLNRKDIMDSLKNEN--FDMVIVET------FDYCPFLIAEKLGKPFVAILSTSF---- 197

  Fly   174 LAGNLAPSVYEPISPNGFALDNTFLSRWSNWIYITEEKLLERLVFRPAQVRLFKKFFGYPAEK-- 236
              |:|...:..|:|                ::.:....|.:.:.|. .:|:.|..||.:...:
Human   198 --GSLEFGLPIPLS----------------YVPVFRSLLTDHMDFW-GRVKNFLMFFSFCRRQQH 243

  Fly   237 --------------------LDELRARFSVILVNSHFSMGRVRANVPNIIEVAGVHLSEPPEPCG 281
                                |..|..:..:..:||.|:....|..:||.:.|.|: :.:|.:|..
Human   244 MQSTFDNTIKEHFTEGSRPVLSHLLLKAELWFINSDFAFDFARPLLPNTVYVGGL-MEKPIKPVP 307

  Fly   282 AELQKYLDE-AEHGAIYFSMGQDILIKYLPENMQKQLLLVFLQMKQRVIWKSELSML---ANKSE 342
            .:|:.::.: .:.|.:..::|..:.....|| :.|::...|..:.|.||||.:.|..   .:.:.
Human   308 QDLENFIAKFGDSGFVLVTLGSMVNTCQNPE-IFKEMNNAFAHLPQGVIWKCQCSHWPKDVHLAA 371

  Fly   343 NIYVMDKVPQRMVLAHPNLRLFITHGGLQSVMEAIDNGVPMLGLPLFFDQFNNIHRVQLAGMAKV 407
            |:.::|.:||..:||||::|||:||||..|:||||.:||||:|:|||.||..|:.||:.......
Human   372 NVKIVDWLPQSDLLAHPSIRLFVTHGGQNSIMEAIQHGVPMVGIPLFGDQPENMVRVEAKKFGVS 436

  Fly   408 LDPNDLNADTLIETIKELLENPSYAQRAKEMAASFRDRPMSPLDTAIWWTEYALRNRDTSHMRLN 472
            :....|.|:||...:|:::|:..|...|...:...|..|:||....:.|.::.|:....:|::..
Human   437 IQLKKLKAETLALKMKQIMEDKRYKSAAVAASVILRSHPLSPTQRLVGWIDHVLQTGGATHLKPY 501

  Fly   473 VEEIPLMRYYRLD-SILTFGVRLGC--VCGSLIFLG-WRLYQKNRNRHT 517
            |.:.|....|.|| .:...|:.||.  :||.|:.:. |.|....:.:.|
Human   502 VFQQPWHEQYLLDVFVFLLGLTLGTLWLCGKLLGMAVWWLRGARKVKET 550

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303B2	NP_651154.1	egt	24..464	CDD:223071	120/508 (24%)
UGT3A2	XP_011512290.1	UDPGT	23..518	CDD:278624	125/531 (24%)
		egt	<162..517	CDD:223071	97/387 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150553
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.740