Protein Alignment Ugt303B2 and UGT3A1

DIOPT Version :10

• Sequence 1: NP_651154.1
• Gene: Ugt303B2 / 42776
• FlyBaseID: FBgn0039087
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: XP_047272663.1
• Gene: UGT3A1 / 133688
• HGNCID: 26625
• Length: 526
• Species: Homo sapiens
• Alignment Length: 525
• Identity: 119/525 - (22%)
• Similarity: 221/525 - (42%)
• Gaps: 111/525 - (21%)

  Fly    38 SPFQMVRPLIKALVERGHKVTMV------------------------TPADYPAKIDGVRHIRVP 78
            |.:.::..:.:.|.|.||.|||:                        :|.|:..:|.  :|.
Human    37 SHYLLLDRVSQILQEHGHNVTMLHQSGKFLIPDIKEEEKSYQVIRWFSPEDHQKRIK--KHF--- 96

  Fly    79 MLNQLMQNLMKNDQFFDALGDKWREG---VLVSTIFYNVSHAILNNNGVQMLMRDKSIRFDMIMV 140
                        |.:.:...|..:|.   |.:..||......:|:...:...:::::  :|::.|
Human    97 ------------DSYIETALDGRKESEALVKLMEIFGTQCSYLLSRKDIMDSLKNEN--YDLVFV 147

  Fly   141 EASHLDALYGLAEFYNATLL---GISCMHMTW-HIDYLAGNLAPSVYEPISPNGFALDNTFLSRW 201
            ||      :....|..|..|   .::.:..|: .:|:  |..:|..|.|:.|   :|....:..|
Human   148 EA------FDFCSFLIAEKLVKPFVAILPTTFGSLDF--GLPSPLSYVPVFP---SLLTDHMDFW 201

  Fly   202 SNWIYITEEKLLERLVFRPAQVRLFKKFFGYPAEK----------------------LDELRARF 244
                               .:|:.|..||.:...:                      |..|..:.
Human   202 -------------------GRVKNFLMFFSFSRSQWDMQSTFDNTIKEHFPEGSRPVLSHLLLKA 247

  Fly   245 SVILVNSHFSMGRVRANVPNIIEVAGVHLSEPPEPCGAELQKYL-DEAEHGAIYFSMGQDILIKY 308
            .:..|||.|:....|..:||.:.:.|: :.:|.:|...:|..:: :..:.|.:..:.| .:|..:
Human   248 ELWFVNSDFAFDFARPLLPNTVYIGGL-MEKPIKPVPQDLDNFIANFGDAGFVLVAFG-SMLNTH 310

  Fly   309 LPENMQKQLLLVFLQMKQRVIWKSELSML---ANKSENIYVMDKVPQRMVLAHPNLRLFITHGGL 370
            ..:.:.|::...|..:.|.|||..:.|..   .:.:.|:.::|.:||..:||||::|||:||||.
Human   311 QSQEVLKKMHNAFAHLPQGVIWTCQSSHWPRDVHLATNVKIVDWLPQSDLLAHPSIRLFVTHGGQ 375

  Fly   371 QSVMEAIDNGVPMLGLPLFFDQFNNIHRVQLAGMAKVLDPNDLNADTLIETIKELLENPSYAQRA 435
            .||||||.:||||:|||:..||..|:.||........:..|.:.||||..|:|:::|:..|....
Human   376 NSVMEAIRHGVPMVGLPVNGDQHGNMVRVVAKNYGVSIRLNQVTADTLTLTMKQVIEDKRYKSAV 440

  Fly   436 KEMAASFRDRPMSPLDTAIWWTEYALRNRDTSHMRLNVEEIPLMRYYRLD-SILTFGVRLGC--V 497
            ...:.....:|:||....:.|.::.|:....:|::....:.|....|.:| .:...|:.||.  :
Human   441 VAASVILHSQPLSPAQRLVGWIDHILQTGGATHLKPYAFQQPWHEQYLIDVFVFLLGLTLGTMWL 505

  Fly   498 CGSLI 502
            ||.|:
Human   506 CGKLL 510

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303B2	NP_651154.1	Glycosyltransferase_GTB-type	24..464	CDD:471961	109/482 (23%)
UGT3A1	XP_047272663.1	Glycosyltransferase_GTB-type	36..526	CDD:471961	119/525 (23%)