Protein Alignment Ugt303B2 and UGT2B11

DIOPT Version :9

• Sequence 1: NP_651154.1
• Gene: Ugt303B2 / 42776
• FlyBaseID: FBgn0039087
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: NP_001064.1
• Gene: UGT2B11 / 10720
• HGNCID: 12545
• Length: 529
• Species: Homo sapiens
• Alignment Length: 554
• Identity: 142/554 - (25%)
• Similarity: 261/554 - (47%)
• Gaps: 81/554 - (14%)

  Fly     7 WLAFGLLLHLNLYLELGQAANILGVFPYRIPSPFQMVRPLIKALVERGHKVTMVT--------PA 63
            |.:..||:||:.|...|....:| |:.... |.:..::.::|.||:|||:||::.        |.
Human     5 WTSVLLLIHLSCYFSSGSCGKVL-VWAAEY-SHWMNMKTILKELVQRGHEVTVLASSASILFDPN 67

  Fly    64 D--------YPAKIDGVRHIRVPMLNQLMQNL-----MKNDQFFDALGDK----WREGVLVSTIF 111
            |        ||..:     .:....|.:||.:     ::.|.|:.....:    |.    :..||
Human    68 DASTLKFEVYPTSL-----TKTEFENIIMQQVKRWSDIRKDSFWLYFSQEQEILWE----LYDIF 123

  Fly   112 YNVSHAILNNNGVQMLMRDKSIRFDMIMVEASHLDALYGLAEFYNATLLGISCMHMT-----WHI 171
            .|....:::|..|...:::.  |||::..     ||::...|.. |.||.|..::..     :.|
Human   124 RNFCKDVVSNKKVMKKLQES--RFDIVFA-----DAVFPCGELL-AALLNIRFVYSLRFTPGYTI 180

  Fly   172 DYLAGNLA-PSVYEPISPNGFALDNTFLSRWSNWIYITEEKLLERLVFRPAQVRLFKKFF----G 231
            :..:|.|. |..|.||..:..:...||:.|..|.||:    |.....|:.:.::.:.:|:    |
Human   181 ERHSGGLIFPPSYIPIVMSKLSDQMTFMERVKNMIYV----LYFDFWFQMSDMKKWDQFYSEVLG 241

  Fly   232 YPAEKLDELRARFSVILVNSHFSMGRVRANVPNIIEVAGVHLSEPPEPCGAELQKYLDEA-EHGA 295
            .|. .|.|...:..:.|:.:.:|.......:||:..|.|.| .:|.:|...|:::::..: |:|.
Human   242 RPT-TLFETMGKADIWLMRNSWSFQFPHPFLPNVDFVGGFH-CKPAKPLPKEMEEFVQSSGENGV 304

  Fly   296 IYFSMGQDILIKYLPENMQKQLLLVFLQMKQRVIWKSELSMLANKSE----NIYVMDKVPQRMVL 356
            :.||:|.  :|..:.......:.....::.|:|:|:.:    .||.:    |..:...:||..:|
Human   305 VVFSLGS--VISNMTAERANVIATALAKIPQKVLWRFD----GNKPDALGLNTRLYKWIPQNDLL 363

  Fly   357 AHPNLRLFITHGGLQSVMEAIDNGVPMLGLPLFFDQFNNIHRVQLAGMAKVLDPNDLNADTLIET 421
            .||..|.||||||...:.|||.:|:||:|:||||||.:||..::..|.|..||.|.:::..|:..
Human   364 GHPKTRAFITHGGANGIYEAIYHGIPMVGIPLFFDQPDNIAHMKAKGAAVRLDFNTMSSTDLLNA 428

  Fly   422 IKELLENPSYAQRAKEMAASFRDRPMSPLDTAIWWTEYALRNRDTSHMRLNVEEIPLMRYYRLDS 486
            :|.::.:|.|.:...:::....|:|:.|||.|::|.|:.:.::...|:|:...::...:|:.||.
Human   429 LKTVINDPLYKENIMKLSRIQHDQPVKPLDRAVFWIEFVMPHKGAKHLRVAAHDLTWFQYHSLDV 493

  Fly   487 ILTFGVRLGCVCGSL-------IFLGWRLYQKNR 513
            |   |..|.||...:       :|..|:..:|.:
Human   494 I---GFLLACVATVIFIITKFCLFCFWKFARKGK 524

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303B2	NP_651154.1	egt	24..464	CDD:223071	122/479 (25%)
UGT2B11	NP_001064.1	UDPGT	24..525	CDD:278624	135/535 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150494
Domainoid	1	1.000	260	1.000	Domainoid score	I1978
eggNOG	1	0.900	-	-		E33208_3BDT1
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	267	1.000	Inparanoid score	I3041
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	9	8.690