DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt303B2 and ugt5f1

DIOPT Version :9

Sequence 1:	NP_651154.1	Gene:	Ugt303B2 / 42776	FlyBaseID:	FBgn0039087	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	XP_017207383.1	Gene:	ugt5f1 / 100415800	ZFINID:	ZDB-GENE-100406-6	Length:	556	Species:	Danio rerio

Alignment Length:	527	Identity:	144/527 - (27%)
Similarity:	254/527 - (48%)	Gaps:	64/527 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 LLLHLNLYLELGQAANILGVFPYRIPSPFQMVRPLIKALVERGHKVTMVTPAD---YPAKIDGVR 73
            ::|.|.|.:..|:   || |||:. .|.:..:..||:.|..|||:::::...|   .|.......
Zfish    41 VVLSLTLPVHCGK---IL-VFPHE-GSHWLNLNTLIEELHHRGHQISVIRALDSWYIPETSPHYD 100

  Fly    74 HIRVPMLNQLMQNLMKNDQFFDA----------------------LGDKWREGVLVSTIFYNVSH 116
            .|.||.|      |..:|||:.:                      |.:|:.|  :...|...|.|
Zfish   101 SINVPFL------LGGDDQFYHSFIFRQLQIRREQRWTRFKLDMELKEKFSE--MHRKICEMVIH 157

  Fly   117 AILNNNGVQMLMRDKSIRFDMIMVEASHLDALYGLAEFYNATLLGISCMHMTWHID---YLAGNL 178
            .:.....:  :.:.|...||:::.:.::...:. ||.:.:..|:    .::.|.:.   :.|...
Zfish   158 IVEKEPAI--MKQIKEANFDIMLTDPANGGGVV-LAHYLHLPLV----FNVQWTVHGEAHFAIAP 215

  Fly   179 APSVYEPISPNGFALDNTFLSRWSNWIYITEEKLLERLVFRPAQVRLFKKFFGYPAEKLDELRAR 243
            :|..|.|...:......:|..|..|.::......|.|....|....|..:.|| |.....||...
Zfish   216 SPPSYVPFPLSQLTDSMSFPQRIYNVLFSAVRLFLYRRTVGPHYSALCNRLFG-PGLDYFELFQA 279

  Fly   244 FSVILVNSHFSMGRVRANVPNIIEVAGVHLSEPPEPCGAELQKYLDEA-EHGAIYFSMGQDILIK 307
            ..:.|:.:.|.....|..:||:|.:.|.|.| |.:....:|:.:|..: |||.|..|:|  .|:.
Zfish   280 ADIWLMRADFVFDFPRPTMPNVIYIGGFHCS-PAKALPKDLEDFLQSSGEHGVIVMSLG--TLVA 341

  Fly   308 YLPENMQKQLLLVFLQMKQRVIWKSELSMLANKSENIYVMDKVPQRMVLAHPNLRLFITHGGLQS 372
            .||.::..:::..|.::.|:|||:......||...|..:::.:||..:|.||..|:|::|||...
Zfish   342 QLPMDIADEIVAAFAELPQKVIWRYTGDRPANVGNNTLLVNWLPQNDLLGHPKTRVFVSHGGTNG 406

  Fly   373 VMEAIDNGVPMLGLPLFFDQFNNIHRVQLAGMAKVLDPNDLNADTLIETIKELLENPSYAQRAKE 437
            |.|||.:|||::||||.|||..|:.:::..|:|||||...:|.:...:.::|:|.:|||....::
Zfish   407 VFEAIYHGVPIVGLPLVFDQDYNLLKMKHKGVAKVLDIATINRNIFKDALQEVLNDPSYRSNMQK 471

  Fly   438 MAASFRDRPMSPLDTAIWWTEYALRNRDTSHMRLNVEEIPLMRYYRLD------SILTFGVRL-- 494
            :::..:|.|:.|||:|::|||:.:|:|..:|:|.:..::|...|:.:|      |:|.|.|.|
Zfish   472 LSSLHKDTPLKPLDSALFWTEFVMRHRGAAHLRTDSYKMPWYSYHSVDVGVFLVSVLCFIVFLMF 536

  Fly   495 ---GCVC 498
               .|:|
Zfish   537 KIVRCLC 543

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303B2	NP_651154.1	egt	24..464	CDD:223071	127/468 (27%)
ugt5f1	XP_017207383.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170584511
Domainoid	1	1.000	252	1.000	Domainoid score	I2043
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	252	1.000	Inparanoid score	I3189
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	8	7.790