Protein Alignment Ugt303B1 and UGT2A3

DIOPT Version :9

• Sequence 1: NP_651153.1
• Gene: Ugt303B1 / 42775
• FlyBaseID: FBgn0039086
• Length: 519
• Species: Drosophila melanogaster
• Sequence 2: XP_011530549.1
• Gene: UGT2A3 / 79799
• HGNCID: 28528
• Length: 533
• Species: Homo sapiens
• Alignment Length: 528
• Identity: 116/528 - (21%)
• Similarity: 236/528 - (44%)
• Gaps: 97/528 - (18%)

  Fly    35 ISPFFVMQPLVRTLATRGHNVTLITPIGMPNDIEGVRHIRVAQLNERIKEML------------- 86
            :|.:..::.::..|..|||.||::|            |.:.:.::.|....|
Human    33 MSHWLNVKVILEELIVRGHEVTVLT------------HSKPSLIDYRKPSALKFEVVHMPQDRTE 85

  Fly    87 ESDQVLDFMINKWTESALTAKALFNASNDILSDPGVQRMLHD------------KSESFDLIIME 139
            |::..:|..:|. .....|.:::...::..:...|..:|:.:            :..::|:::::
Human    86 ENEIFVDLALNV-LPGLSTWQSVIKLNDFFVEIRGTLKMMCESFIYNQTLMKKLQETNYDVMLID 149

  Fly   140 P----SSLDALYGLVEFYNATLMGLSSIRINWHTYELAGN--------PAPSIYEPISPVGFSLE 192
            |    ..|.|....|.|       :.::||:     :.||        |||..|.|:...|.:..
Human   150 PVIPCGDLMAELLAVPF-------VLTLRIS-----VGGNMERSCGKLPAPLSYVPVPMTGLTDR 202

  Fly   193 TSLFSRVYNWIHIMEEKLVNYLILRPAQLHLFQKFFGYSAQK---MNELRSRFSLMLINSHYSMG 254
            .:...||.|   .|...|.::.| :....|.:::|:..:..:   :.|...:..:.||.:::...
Human   203 MTFLERVKN---SMLSVLFHFWI-QDYDYHFWEEFYSKALGRPTTLCETVGKAEIWLIRTYWDFE 263

  Fly   255 KVRANAPNIIEVGGLHLSEPPEPSD---------EELQKFLDKA-DHGVIYFSMGNDILIKFLPE 309
            ..:...||...|||||.    :|:.         :|::.|:..: :.|::.||:|:  |.:.:.|
Human   264 FPQPYQPNFEFVGGLHC----KPAKALPKINFYLQEMENFVQSSGEDGIVVFSLGS--LFQNVTE 322

  Fly   310 NIQELLLQTFATLNESIIWKSELLYMPDKSD----NVYVVEQAPQRHILNHPNVRLFITNGGLLS 370
            ....::....|.:.:.::|:    |...|..    |..:.:..||..:|.||..:.|||:||:..
Human   323 EKANIIASALAQIPQKVLWR----YKGKKPSTLGANTRLYDWIPQNDLLGHPKTKAFITHGGMNG 383

  Fly   371 VIEAVDSGVPMLGLPMFFDQFGNMRWVQLSGMAEVMDINSLNKDTLTETIKHMLANNSYYLKAKE 435
            :.||:..||||:|:|:|.||..|:..::..|.|..::..::..:.|...::.::.::||...|..
Human   384 IYEAIYHGVPMVGVPIFGDQLDNIAHMKAKGAAVEINFKTMTSEDLLRALRTVITDSSYKENAMR 448

  Fly   436 ISQFFKDRPMSPLDTAVWWTEYALRNRNITRMRLNLEEIPLIEYYRIDSILAFSLRFGLVAASLI 500
            :|:...|:|:.|||.||:|.|:.:|::....:|....::...::|.|| ::.|.|   ...|:.|
Human   449 LSRIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRSAAHDLTWFQHYSID-VIGFLL---ACVATAI 509

  Fly   501 FLVYTLFL 508
            ||....||
Human   510 FLFTKCFL 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303B1	NP_651153.1	egt	21..462	CDD:223071	104/480 (22%)
		UDPGT	41..511	CDD:278624	115/522 (22%)
UGT2A3	XP_011530549.1	UDPGT	24..528	CDD:278624	116/528 (22%)
		egt	<267..498	CDD:223071	64/241 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150231
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BDT1
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	267	1.000	Inparanoid score	I3041
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	8	7.690