Protein Alignment Ugt303B1 and UGT8

DIOPT Version :9

• Sequence 1: NP_651153.1
• Gene: Ugt303B1 / 42775
• FlyBaseID: FBgn0039086
• Length: 519
• Species: Drosophila melanogaster
• Sequence 2: NP_001121646.2
• Gene: UGT8 / 7368
• HGNCID: 12555
• Length: 541
• Species: Homo sapiens
• Alignment Length: 509
• Identity: 139/509 - (27%)
• Similarity: 249/509 - (48%)
• Gaps: 38/509 - (7%)

  Fly    21 AQAANILGIFPYRHISPFFVMQPLVRTLATRGHNVTLITPIGMPNDIEGVRHIRVAQLNERIKEM 85
            |:||.|:.:.|....|..::.:.|...|..|||:...:...|  .||....|..: |....|...
Human    18 AKAAKIIIVPPIMFESHMYIFKTLASALHERGHHTVFLLSEG--RDIAPSNHYSL-QRYPGIFNS 79

  Fly    86 LESDQVLDFMINKWTESALTAKALFNASNDILSD--------PGVQRMLHD-KSESFDLIIMEPS 141
            ..||..|...:.......|||..||    |||..        .|...::.. |.|.|||::::|:
Human    80 TTSDAFLQSKMRNIFSGRLTAIELF----DILDHYTKNCDLMVGNHALIQGLKKEKFDLLLVDPN 140

  Fly   142 SLDALYGLVEFYNATLMGLSSIRIN---WHTYELAGNPAPSIYEPISPVGFSLETSLFSRVYN-W 202
            .      :..|..|.|:|:.....:   |:..|: |.|||..|.|......:...:|..|:.| .
Human   141 D------MCGFVIAHLLGVKYAVFSTGLWYPAEV-GAPAPLAYVPEFNSLLTDRMNLLQRMKNTG 198

  Fly   203 IHIMEEKLVNYLILRPAQLHLFQKFFGYSAQKMNELRSRFSLMLINSHYSMGKVRANAPNIIEVG 267
            ::::....|::|:| |....:.||:.....:.|.:|....||.::.:..::...|...||::.||
Human   199 VYLISRLGVSFLVL-PKYERIMQKYNLLPEKSMYDLVHGSSLWMLCTDVALEFPRPTLPNVVYVG 262

  Fly   268 GLHLSEPPEPSDEELQKFLDKA-DHGVIYFSMGNDILIKFLPENIQELLLQTFATLNESIIWKSE 331
            |: |::|..|..|:||::::.| :||.:..|.|..  :|:|.|:|...|......|.:.:||:..
Human   263 GI-LTKPASPLPEDLQRWVNGANEHGFVLVSFGAG--VKYLSEDIANKLAGALGRLPQKVIWRFS 324

  Fly   332 LLYMPDKSDNVYVVEQAPQRHILNHPNVRLFITNGGLLSVIEAVDSGVPMLGLPMFFDQFGNMRW 396
            .....:..:|..::|..||..:|.|..::.|:::|||.|:.|.:..|||::|:|:|.|.:..|..
Human   325 GPKPKNLGNNTKLIEWLPQNDLLGHSKIKAFLSHGGLNSIFETIYHGVPVVGIPLFGDHYDTMTR 389

  Fly   397 VQLSGMAEVMDINSLNKDTLTETIKHMLANNSYYLKAKEISQFFKDRPMSPLDTAVWWTEYALRN 461
            ||..||..:::..::.:..|.|.:..::.|.||..:|:::|:..||:|..|::..::|.:|.:|:
Human   390 VQAKGMGILLEWKTVTEKELYEALVKVINNPSYRQRAQKLSEIHKDQPGHPVNRTIYWIDYIIRH 454

  Fly   462 RNITRMRLNLEEIPLIEYYRIDSILAFSLRFGLVAASLIFLV--YTLFLKYRIR 513
            .....:|..:.:|...:|:.:|  :||.|..|  ||.|.||:  .|.|:..:|:
Human   455 NGAHHLRAAVHQISFCQYFLLD--IAFVLLLG--AALLYFLLSWVTKFIYRKIK 504

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303B1	NP_651153.1	egt	21..462	CDD:223071	123/454 (27%)
		UDPGT	41..511	CDD:278624	132/485 (27%)
UGT8	NP_001121646.2	Glycosyltransferase_GTB-type	21..502	CDD:415824	136/502 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150672
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.740