Protein Alignment Ugt303B1 and UGT2B15

DIOPT Version :9

• Sequence 1: NP_651153.1
• Gene: Ugt303B1 / 42775
• FlyBaseID: FBgn0039086
• Length: 519
• Species: Drosophila melanogaster
• Sequence 2: NP_001067.2
• Gene: UGT2B15 / 7366
• HGNCID: 12546
• Length: 530
• Species: Homo sapiens
• Alignment Length: 549
• Identity: 130/549 - (23%)
• Similarity: 252/549 - (45%)
• Gaps: 76/549 - (13%)

  Fly     1 MRLRYCWLTLSLCLLLQHDRAQAANILGIFP--YRHISPFFVMQPLVRTLATRGHNVTLITPIGM 63
            |.|::..:.|.:.|...........:| ::|  |.|   :..|:.::..|..|||.||::|  ..
Human     1 MSLKWTSVFLLIQLSCYFSSGSCGKVL-VWPTEYSH---WINMKTILEELVQRGHEVTVLT--SS 59

  Fly    64 PNDIEGVRHIRVAQL----NERIKEMLESD--QVLD---FMINK---WTESALTAK---ALFNAS 113
            .:.:.........:|    ....|..||..  ::||   :.::|   |:..:...:   ..::.|
Human    60 ASTLVNASKSSAIKLEVYPTSLTKNYLEDSLLKILDRWIYGVSKNTFWSYFSQLQELCWEYYDYS 124

  Fly   114 NDILSDPGVQR--MLHDKSESFDLIIMEPSSLDALYG----LVEFYNATLMGLSSIRIN-WHTYE 171
            |.:..|..:.:  |:..:...||:|:     .|||..    |.|.:|...  |.|:|.: .:|:|
Human   125 NKLCKDAVLNKKLMMKLQESKFDVIL-----ADALNPCGELLAELFNIPF--LYSLRFSVGYTFE 182

  Fly   172 LAGNP--APSIYEPISPVGFSLETSLFSRVYNWIHIME-------------EKLVNYLILRPAQL 221
            ..|..  .|..|.|:.....|.:.....|:.|.||::.             ::..:.::.||..|
Human   183 KNGGGFLFPPSYVPVVMSELSDQMIFMERIKNMIHMLYFDFWFQIYDLKKWDQFYSEVLGRPTTL 247

  Fly   222 HLFQKFFGYSAQKMNELRSRFSLMLINSHYSMGKVRANAPNIIEVGGLHLSEPPEPSDEELQKFL 286
            .              |...:..:.||.:::.....|...||:..||||| .:|.:|..:|:::|:
Human   248 F--------------ETMGKAEMWLIRTYWDFEFPRPFLPNVDFVGGLH-CKPAKPLPKEMEEFV 297

  Fly   287 DKA-DHGVIYFSMGNDILIKFLPENIQELLLQTFATLNESIIWKSELLYMPDKSDNVYVVEQAPQ 350
            ..: ::|::.||:|:  :|..:.|....::....|.:.:.::|:.:.........|..:.:..||
Human   298 QSSGENGIVVFSLGS--MISNMSEESANMIASALAQIPQKVLWRFDGKKPNTLGSNTRLYKWLPQ 360

  Fly   351 RHILNHPNVRLFITNGGLLSVIEAVDSGVPMLGLPMFFDQFGNMRWVQLSGMAEVMDINSLNKDT 415
            ..:|.||..:.|||:||...:.||:..|:||:|:|:|.||..|:..::..|.|..:||.:::...
Human   361 NDLLGHPKTKAFITHGGTNGIYEAIYHGIPMVGIPLFADQHDNIAHMKAKGAALSVDIRTMSSRD 425

  Fly   416 LTETIKHMLANNSYYLKAKEISQFFKDRPMSPLDTAVWWTEYALRNRNITRMRLNLEEIPLIEYY 480
            |...:|.::.:..|.....::|:...|:||.|||.||:|.|:.:|::....:|:....:..|:|:
Human   426 LLNALKSVINDPVYKENVMKLSRIHHDQPMKPLDRAVFWIEFVMRHKGAKHLRVAAHNLTWIQYH 490

  Fly   481 RIDSILAFSLRFGLVAASLIFLV--YTLF 507
            .:| ::||.|   ...|::||::  :.||
Human   491 SLD-VIAFLL---ACVATVIFIITKFCLF 515

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303B1	NP_651153.1	egt	21..462	CDD:223071	114/480 (24%)
		UDPGT	41..511	CDD:278624	122/507 (24%)
UGT2B15	NP_001067.2	egt	8..508	CDD:223071	125/533 (23%)
		UDPGT	24..518	CDD:278624	126/526 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150282
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BDT1
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	267	1.000	Inparanoid score	I3041
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	8	7.690