Protein Alignment Ugt303B1 and UGT2B10

DIOPT Version :9

• Sequence 1: NP_651153.1
• Gene: Ugt303B1 / 42775
• FlyBaseID: FBgn0039086
• Length: 519
• Species: Drosophila melanogaster
• Sequence 2: NP_001066.1
• Gene: UGT2B10 / 7365
• HGNCID: 12544
• Length: 528
• Species: Homo sapiens
• Alignment Length: 512
• Identity: 116/512 - (22%)
• Similarity: 234/512 - (45%)
• Gaps: 91/512 - (17%)

  Fly    41 MQPLVRTLATRGHNVTLITPIGM----PND-----------------IEGVRHIRVAQLNERIKE 84
            |:.:::.|..|||.||::.....    |||                 .|.:    :.||.:|:.|
Human    38 MKTILKELVQRGHEVTVLASSASILFDPNDSSTLKLEVYPTSLTKTEFENI----IMQLVKRLSE 98

  Fly    85 MLESDQVLDFMINK---WTESALTAKALFNASNDILSDPGVQRMLHDKSESFDLIIMEPSSLDAL 146
            :.:....|.|...:   |..:.:    :.|...|::|:..:.:.|.:  ..||::..: :.|...
Human    99 IQKDTFWLPFSQEQEILWAINDI----IRNFCKDVVSNKKLMKKLQE--SRFDIVFAD-AYLPCG 156

  Fly   147 YGLVEFYNATLM-------GLSSIRINWHTYELAGNPAPSIYEPISPVGFSLETSLFSRVYNWIH 204
            ..|.|.:|...:       |.|..|   |:   .|...|..|.|:.....|.:.:...||.|.::
Human   157 ELLAELFNIPFVYSHSFSPGYSFER---HS---GGFIFPPSYVPVVMSKLSDQMTFMERVKNMLY 215

  Fly   205 IME-------------EKLVNYLILRPAQLHLFQKFFGYSAQKMNELRSRFSLMLINSHYSMGKV 256
            ::.             ::..:.::.||..|              :|...:..:.|:.:.::....
Human   216 VLYFDFWFQIFNMKKWDQFYSEVLGRPTTL--------------SETMRKADIWLMRNSWNFKFP 266

  Fly   257 RANAPNIIEVGGLHLSEPPEPSDEELQKFLDKA-DHGVIYFSMGNDILIKFLPENIQELLLQTFA 320
            ....||:..||||| .:|.:|..:|:::|:..: ::||:.||:|:  ::..:.|....::....|
Human   267 HPFLPNVDFVGGLH-CKPAKPLPKEMEEFVQSSGENGVVVFSLGS--MVSNMTEERANVIATALA 328

  Fly   321 TLNESIIWKSELLYMPDKSD----NVYVVEQAPQRHILNHPNVRLFITNGGLLSVIEAVDSGVPM 381
            .:.:.::|:    :..:|.|    |..:.:..||..:|.||..|.|||:||...:.||:..|:||
Human   329 KIPQKVLWR----FDGNKPDALGLNTRLYKWIPQNDLLGHPKTRAFITHGGANGIYEAIYHGIPM 389

  Fly   382 LGLPMFFDQFGNMRWVQLSGMAEVMDINSLNKDTLTETIKHMLANNSYYLKAKEISQFFKDRPMS 446
            :|:|:||||..|:..::..|.|..:|.|:::...|...:|.::.:.||.....::|:...|:|:.
Human   390 VGIPLFFDQPDNIAHMKAKGAAVRVDFNTMSSTDLLNALKTVINDPSYKENIMKLSRIQHDQPVK 454

  Fly   447 PLDTAVWWTEYALRNRNITRMRLNLEEIPLIEYYRIDSILAFSLRFGLVAASLIFLV 503
            |||.||:|.|:.:|::....:|:....:...:|:.:| ::.|.|   ...|:::|::
Human   455 PLDRAVFWIEFVMRHKGAKHLRVAAHNLTWFQYHSLD-VIGFLL---ACVATVLFII 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303B1	NP_651153.1	egt	21..462	CDD:223071	109/469 (23%)
		UDPGT	41..511	CDD:278624	116/512 (23%)
UGT2B10	NP_001066.1	UDPGT	23..524	CDD:278624	116/512 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150490
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BDT1
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	267	1.000	Inparanoid score	I3041
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	8	7.690