Protein Alignment Ugt303B1 and UGT2B4

DIOPT Version :9

• Sequence 1: NP_651153.1
• Gene: Ugt303B1 / 42775
• FlyBaseID: FBgn0039086
• Length: 519
• Species: Drosophila melanogaster
• Sequence 2: NP_066962.2
• Gene: UGT2B4 / 7363
• HGNCID: 12553
• Length: 528
• Species: Homo sapiens
• Alignment Length: 554
• Identity: 123/554 - (22%)
• Similarity: 246/554 - (44%)
• Gaps: 113/554 - (20%)

  Fly    11 SLCLLLQ----HDRAQAANILGIFPYRHISPFFVMQPLVRTLATRGHNVTLIT------------ 59
            |..||:|    ........:| ::| ...|.:..::.::..|..|||.||::.
Human     7 SALLLIQLSCYFSSGSCGKVL-VWP-TEFSHWMNIKTILDELVQRGHEVTVLASSASISFDPNSP 69

  Fly    60 --------PIGM-PNDIEGVRHIRVAQLNERIKEMLES------DQVLDFMINKWTESALTAKAL 109
                    |:.: ..:.|.:    :.||.:|..|:.:.      .||.:.|   ||.:.:..|
Human    70 STLKFEVYPVSLTKTEFEDI----IKQLVKRWAELPKDTFWSYFSQVQEIM---WTFNDILRK-- 125

  Fly   110 FNASNDILSDPGVQRMLHDKSESFDLIIMEPSSLDALYGLVEFYNATLMGLSSIRINWHTYELAG 174
              ...||:|:..:.:.|.:  ..||:::     .||::...|.. |.|:.:..:      |.|..
Human   126 --FCKDIVSNKKLMKKLQE--SRFDVVL-----ADAVFPFGELL-AELLKIPFV------YSLRF 174

  Fly   175 NPA------------PSIYEPISPVGFSLETSLFSRVYNWIHIME-------------EKLVNYL 214
            :|.            |..|.|:.....|.:.:...||.|.|:::.             ::..:.:
Human   175 SPGYAIEKHSGGLLFPPSYVPVVMSELSDQMTFIERVKNMIYVLYFEFWFQIFDMKKWDQFYSEV 239

  Fly   215 ILRPAQLHLFQKFFGYSAQKMNELRSRFSLMLINSHYSMGKVRANAPNIIEVGGLHLSEPPEPSD 279
            :.||..|              :|..::..:.||.:::.........||:..||||| .:|.:|..
Human   240 LGRPTTL--------------SETMAKADIWLIRNYWDFQFPHPLLPNVEFVGGLH-CKPAKPLP 289

  Fly   280 EELQKFLDKA-DHGVIYFSMGNDILIKFLPENIQELLLQTFATLNESIIWKSELLYMPDKSD--- 340
            :|:::|:..: ::||:.||:|:  ::....|....::....|.:.:.::|:    :..:|.|
Human   290 KEMEEFVQSSGENGVVVFSLGS--MVSNTSEERANVIASALAKIPQKVLWR----FDGNKPDTLG 348

  Fly   341 -NVYVVEQAPQRHILNHPNVRLFITNGGLLSVIEAVDSGVPMLGLPMFFDQFGNMRWVQLSGMAE 404
             |..:.:..||..:|.||..|.|||:||...:.||:..|:||:|:|:|.||..|:..::..|.|.
Human   349 LNTRLYKWIPQNDLLGHPKTRAFITHGGANGIYEAIYHGIPMVGVPLFADQPDNIAHMKAKGAAV 413

  Fly   405 VMDINSLNKDTLTETIKHMLANNSYYLKAKEISQFFKDRPMSPLDTAVWWTEYALRNRNITRMRL 469
            .:|.::::...|...:|.::.:..|...|.::|:...|:|:.|||.||:|.|:.:|::....:|:
Human   414 SLDFHTMSSTDLLNALKTVINDPLYKENAMKLSRIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRV 478

  Fly   470 NLEEIPLIEYYRIDSILAFSLRFGLVAASLIFLV 503
            ...::...:|:.:| :..|.|   ...|::||::
Human   479 AAHDLTWFQYHSLD-VTGFLL---ACVATVIFII 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303B1	NP_651153.1	egt	21..462	CDD:223071	111/497 (22%)
		UDPGT	41..511	CDD:278624	116/520 (22%)
UGT2B4	NP_066962.2	egt	8..512	CDD:223071	122/553 (22%)
		UDPGT	24..524	CDD:278624	119/537 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150438
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BDT1
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	267	1.000	Inparanoid score	I3041
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	8	7.690