Protein Alignment Ugt303B1 and Ugt2a3

DIOPT Version :9

• Sequence 1: NP_651153.1
• Gene: Ugt303B1 / 42775
• FlyBaseID: FBgn0039086
• Length: 519
• Species: Drosophila melanogaster
• Sequence 2: NP_082370.2
• Gene: Ugt2a3 / 72094
• MGIID: 1919344
• Length: 534
• Species: Mus musculus
• Alignment Length: 565
• Identity: 133/565 - (23%)
• Similarity: 244/565 - (43%)
• Gaps: 107/565 - (18%)

  Fly     3 LRYCWLTLSLCLLLQHDRAQAANILGIFPYRHISPFFVMQPLVRTLATRGHNVTLI--------- 58
            |:.||.....|          :.:| ::|. .:|.:..::.::..|..|||.||::
Mouse    13 LQLCWAGCGFC----------SKVL-VWPC-DMSHWLNLKTILEELGARGHEVTVLKYPSIIIDQ 65

  Fly    59 ---TPIGMPN-----DIEGVRHIRVAQLNERIKEMLESDQVLDFMIN------KWTESALTAKAL 109
               .|:...|     :||...:    :|||          :.:..:|      .| |:|.|.:..
Mouse    66 SKRIPLHFENIPLLYEIETAEN----RLNE----------IANLAVNVIPNLSLW-EAAKTLQDF 115

  Fly   110 F--------NASNDILSDPGVQRMLHDKSESFDLIIMEP----SSLDALYGLVEFYNATLMGLSS 162
            |        :....:|.:......|.|  ..:|:::::|    ..|.|....:.|. .||.....
Mouse   116 FLQVTGDFESICRSVLYNQKFMDKLRD--AQYDVVVIDPVVPCGELVAEVLQIPFV-YTLRFSMG 177

  Fly   163 IRINWHTYELAGNPAPSIYEPISPVGFSLETSLFSRVYNWIHIMEEKLVNYLILRPAQLHLFQKF 227
            ..:..|..:|   |.|..|.|:.....:...:...||.|   :|...|..|        .|.|..
Mouse   178 YYMEKHCGQL---PIPLSYVPVVMSELTDNMTFTERVKN---MMFSLLFEY--------WLQQYD 228

  Fly   228 FGYSAQKMNELRSR----------FSLMLINSHYSMGKVRANAPNIIEVGGLHLSEPPEPSDEEL 282
            |.:..|..:|...|          ..:.||.:::.:...|...||...||||| .:|.:|..:|:
Mouse   229 FAFWDQFYSETLGRPTTFCKTVGKADIWLIRTYWDVEFPRPYLPNFEFVGGLH-CKPAKPLPKEM 292

  Fly   283 QKFLDKA-DHGVIYFSMGNDILIKFLPENIQELLLQTFATLNESIIWKSELLYMPDK----SDNV 342
            ::|:..: :|||:.||:|:  ::|.|.|....|:....|.:.:.::|:    |...|    ..|.
Mouse   293 EEFVQSSGEHGVVVFSLGS--MVKNLTEEKANLIASVLAQIPQKVLWR----YSGKKPATLGSNT 351

  Fly   343 YVVEQAPQRHILNHPNVRLFITNGGLLSVIEAVDSGVPMLGLPMFFDQFGNMRWVQLSGMAEVMD 407
            .:....||..:|.||..:.|||:||...:.||:..||||:|:||..||..|:..::..|.|..:.
Mouse   352 RLFNWIPQNDLLGHPKTKAFITHGGTNGIYEAIYHGVPMVGVPMLGDQPHNIAHMEAKGAALKVS 416

  Fly   408 INSLNKDTLTETIKHMLANNSYYLKAKEISQFFKDRPMSPLDTAVWWTEYALRNRNITRMRLNLE 472
            |:::....|...::.::...||...|..:|:...|:|:.|||.||:|.|:.:|::....:|:...
Mouse   417 ISTMTSTDLLSAVRAVINEPSYKENAMRLSRIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAH 481

  Fly   473 EIPLIEYYRIDSILAFSLRFGLVAASLIFLV--YTLFLKYRIRLR 515
            ::...:|:.:| ::.|.|   |...:|.|::  :.||:..::.::
Mouse   482 DLSWFQYHSLD-VIGFLL---LCVVTLTFIITKFCLFVCQKLYMK 522

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303B1	NP_651153.1	egt	21..462	CDD:223071	119/490 (24%)
		UDPGT	41..511	CDD:278624	126/521 (24%)
Ugt2a3	NP_082370.2	UDPGT	25..526	CDD:278624	129/543 (24%)
		egt	<268..507	CDD:223071	74/249 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167840282
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BDT1
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.640