DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt303B1 and ugt5g2

DIOPT Version :9

Sequence 1:	NP_651153.1	Gene:	Ugt303B1 / 42775	FlyBaseID:	FBgn0039086	Length:	519	Species:	Drosophila melanogaster
Sequence 2:	NP_001186305.1	Gene:	ugt5g2 / 556049	ZFINID:	ZDB-GENE-081028-66	Length:	534	Species:	Danio rerio

Alignment Length:	559	Identity:	142/559 - (25%)
Similarity:	252/559 - (45%)	Gaps:	90/559 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MRLRYCWLTLSLCLLLQHDRAQAANILGIFPYRHISPFFVMQPLVRTLATRGHNVTLITPIGMPN 65
            |.|.:.|.:|.|.|...::   |..|| :||... |.:..|:.||:.|.:|||.:::|.   :.:
Zfish     5 MSLVFLWTSLLLSLPSGYN---ADKIL-VFPIDG-SHWVNMEVLVKKLQSRGHELSVIR---LED 61

  Fly    66 D--IEG-------------VRHIRVAQLNERIKEMLES----------DQVLDFM-INKWTESAL 104
            .  |:|             .:.|.:......:|::|::          .|:.:|: |.|....|.
Zfish    62 SWFIKGNSPYYSSITVTLKKKFIDLDLFETAVKKILDARRDGPIMGVLAQMSEFIGILKVGHGAN 126

  Fly   105 TAKALFNASNDILSDPGVQRMLHDKSESFDLIIMEPSSLDALYG---LVEFYNATLMGLSSIRIN 166
            .|.......|.:|       |...|..::||::.:|    |:.|   |..:.:..::    ..:.
Zfish   127 IAMLTSMLENKVL-------MSQIKMANYDLMLTDP----AMPGGVILAHYLHLPMV----YNVR 176

  Fly   167 WHTY---ELAGNPAPSIYEPISPVGFSLETSLFSRVYNWIH----IMEEKLVNYLILRPAQLHLF 224
            |.::   ..:..|:|..:.|:...|.:....|..|..|::|    :::|:   :::: |....|.
Zfish   177 WMSFGEGHFSIAPSPISFVPVPGSGLTDRMGLLERSRNFLHYGLNLIQER---WMVI-PMYTSLL 237

  Fly   225 QKFFGYSAQKMNELRSRFSLMLINSHYSMGKVRANAPNIIEVGGLHLSEPPEPSDEELQKFLDKA 289
            ...|......:...||. .|.|:.:.:.....|.:.||::.:||.. ..|.:|...:|::|:..:
Zfish   238 LNHFPPGTDLLTMQRSA-ELWLVRADFVFEFPRPSMPNLVYIGGFQ-CRPAKPLPADLEEFMQSS 300

  Fly   290 -DHGVIYFSMGNDILIKFLPENIQELLLQTFATLNESIIWK------SELLYMPDKSDNVYVVEQ 347
             ||||:..|:|.  ||..||:.:.|.:...||.:.:.:||:      |.|      .:|..:::.
Zfish   301 GDHGVVVMSLGT--LIAGLPKEVMEAIASAFAQIPQKVIWRFIGQRPSTL------GNNTLLIQW 357

  Fly   348 APQRHILNHPNVRLFITNGGLLSVIEAVDSGVPMLGLPMFFDQFGNMRWVQLSGMAEVMDINSLN 412
            .||..:|.||..|.|:.:||...:.||:..|||:||||:.|||..|:..:|..|.|.::|..:.:
Zfish   358 LPQNDLLGHPKTRAFVAHGGTNGLYEAIYHGVPVLGLPLLFDQLDNIVRLQARGGARMLDAATCS 422

  Fly   413 KDTLTETIKHMLANNSYYLKAKEISQFFKDRPMSPLDTAVWWTEYALRNRNITRMRLNLEEIPLI 477
            .......:..:|.|.:|....:::|...:|||:.|||.||:|.|:.|||:....:|.....:...
Zfish   423 TKEFLVALTDILENPTYRQNMQKLSNLHRDRPLHPLDKAVYWIEFVLRNKGAPHLRAEAYNVSEF 487

  Fly   478 EYYRIDSILAFSLRFGLVAASLIFLVYTLFLKYRIRLRR 516
            .||.:|          :||..|..|:.||...|.|..||
Zfish   488 SYYCLD----------VVALVLFMLLGTLGGVYTICKRR 516

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303B1	NP_651153.1	egt	21..462	CDD:223071	121/483 (25%)
Ugt303B1	NP_651153.1	UDPGT	41..511	CDD:278624	126/512 (25%)
ugt5g2	NP_001186305.1	egt	3..507	CDD:223071	137/548 (25%)
ugt5g2	NP_001186305.1	UDPGT	25..513	CDD:278624	132/531 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170584630
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BDT1
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	252	1.000	Inparanoid score	I3189
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	8	7.690