Protein Alignment Ugt303B1 and UGT2B28

DIOPT Version :9

• Sequence 1: NP_651153.1
• Gene: Ugt303B1 / 42775
• FlyBaseID: FBgn0039086
• Length: 519
• Species: Drosophila melanogaster
• Sequence 2: NP_444267.1
• Gene: UGT2B28 / 54490
• HGNCID: 13479
• Length: 529
• Species: Homo sapiens
• Alignment Length: 529
• Identity: 117/529 - (22%)
• Similarity: 232/529 - (43%)
• Gaps: 100/529 - (18%)

  Fly    32 YRHISPFFVMQPLVRTLATRGHNVTLITPIGM----PNDIEGVR-HIRVAQLNERIKEMLESDQV 91
            |.|   :..|:.:::.|..|||.||::.....    |||...:: .:....|.:     .|.:.:
Human    33 YSH---WMNMKTILKELVQRGHEVTVLASSASILFDPNDAFTLKLEVYPTSLTK-----TEFENI 89

  Fly    92 LDFMINKWTESALTAKALF----------------NASNDILSDPGVQRMLHDKSESFDLIIMEP 140
            :...:.:|::....:..|:                |...|::|:..|.:.|.:  ..||:|.
Human    90 IMQQVKRWSDIQKDSFWLYFSQEQEILWEFHDIFRNFCKDVVSNKKVMKKLQE--SRFDIIF--- 149

  Fly   141 SSLDALYGLVEFYNATLMGLSSIRINWHTYELAGNPA------------PSIYEPISPVGFSLET 193
              .||.:...|.. |.|:.:..:      |.|...|.            |..|.|:.....|.:.
Human   150 --ADAFFPCGELL-AALLNIPFV------YSLCFTPGYTIERHSGGLIFPPSYIPVVMSKLSDQM 205

  Fly   194 SLFSRVYNWIHIME-------------EKLVNYLILRPAQLHLFQKFFGYSAQKMNELRSRFSLM 245
            :...||.|.|:::.             ::..:.::.||..|.              |...:..:.
Human   206 TFMERVKNMIYVLYFDFWFQMCDMKKWDQFYSEVLGRPTTLF--------------ETMGKADIW 256

  Fly   246 LINSHYSMGKVRANAPNIIEVGGLHLSEPPEPSDEELQKFLDKA-DHGVIYFSMGNDILIKFLPE 309
            |:.:.:|........|||..||||| .:|.:|..:|:::|:..: ::||:.||:|:  :|..:..
Human   257 LMRNSWSFQFPHPFLPNIDFVGGLH-CKPAKPLPKEMEEFVQSSGENGVVVFSLGS--VISNMTA 318

  Fly   310 NIQELLLQTFATLNESIIWKSELLYMPDKSD----NVYVVEQAPQRHILNHPNVRLFITNGGLLS 370
            ....::....|.:.:.::|:    :..:|.|    |..:.:..||..:|..|..|.|||:||...
Human   319 ERANVIATALAKIPQKVLWR----FDGNKPDALGLNTRLYKWIPQNDLLGLPKTRAFITHGGANG 379

  Fly   371 VIEAVDSGVPMLGLPMFFDQFGNMRWVQLSGMAEVMDINSLNKDTLTETIKHMLANNSYYLKAKE 435
            :.||:..|:||:|:|:|:||..|:..::..|.|..:|.::::...|...:|.::.:.||.....:
Human   380 IYEAIYHGIPMVGIPLFWDQPDNIAHMKAKGAAVRLDFHTMSSTDLLNALKTVINDPSYKENVMK 444

  Fly   436 ISQFFKDRPMSPLDTAVWWTEYALRNRNITRMRLNLEEIPLIEYYRIDSILAFSLRFGLVAASLI 500
            :|....|:|:.||..||:|.|:.:.::....:|:...::...:|:.:| ::.|.|   ...|::|
Human   445 LSIIQHDQPVKPLHRAVFWIEFVMCHKGAKHLRVAARDLTWFQYHSLD-VIGFLL---ACVATVI 505

  Fly   501 FLV--YTLF 507
            |:|  :.||
Human   506 FVVTKFCLF 514

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303B1	NP_651153.1	egt	21..462	CDD:223071	106/480 (22%)
		UDPGT	41..511	CDD:278624	115/520 (22%)
UGT2B28	NP_444267.1	UDPGT	24..525	CDD:278624	117/529 (22%)
		egt	<269..506	CDD:223071	66/247 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150492
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BDT1
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	267	1.000	Inparanoid score	I3041
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	8	7.690