DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt303B1 and Ugt35C1

DIOPT Version :9

Sequence 1:	NP_651153.1	Gene:	Ugt303B1 / 42775	FlyBaseID:	FBgn0039086	Length:	519	Species:	Drosophila melanogaster
Sequence 2:	NP_001097744.1	Gene:	Ugt35C1 / 53507	FlyBaseID:	FBgn0040256	Length:	517	Species:	Drosophila melanogaster

Alignment Length:	494	Identity:	162/494 - (32%)
Similarity:	276/494 - (55%)	Gaps:	33/494 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 AQAANILGIFPYRHISPFFVMQPLVRTLATRGHNVTLITPI---GMPNDIEGVRHIRVAQLNERI 82
            :::|.||...|:...|.:..::..::.||.:||.||:|...   ..||    :|.|...:.:|..
  Fly    21 SESAKILATLPFPGRSQYIFVESYLKALAAKGHQVTVINAFKNKETPN----MRFIEALKAHEFA 81

  Fly    83 KEML---------ESDQVLDFMINKWTESALTAKALFNASNDILSDPGVQRMLHDKSESFDLIIM 138
            .||:         :....:|:::||:.:..             :.|.||||:| :..|:|||::.
  Fly    82 DEMMSLLNVPLLWQQLNAMDYILNKFIDVT-------------MEDEGVQRLL-NSGETFDLVLA 132

  Fly   139 EPSSLDALYGLVEFYNATLMGLSSIRINWHTYELAGNPAPSIYEPISPVGFSLETSLFSRVYNWI 203
            |...::.:|...:.:||||:|.||...:....|.|||.:|..|.|:.....:...:...|:.|..
  Fly   133 EMLHMEPMYAFAQHFNATLVGFSSFGTDRTIDEAAGNISPISYNPLVTSPRTDRMTFLERLENHY 197

  Fly   204 HIMEEKLVNYLILRPAQLHLFQKFFGYSAQKMNELRSRFSLMLINSHYSMGKVRANAPNIIEVGG 268
            .::.|.:..:.:..|...::::|:|..:.:.:.|:...|||:|:..|:|:...|...||:|||||
  Fly   198 EVIVEDIHRHFVHLPHMRNVYKKYFPNAKKTLEEVMDSFSLILLGQHFSLSYPRPYLPNMIEVGG 262

  Fly   269 LHLSEPPEPSDEELQKFLDKADHGVIYFSMGNDILIKFLPENIQELLLQTFATLNESIIWKSELL 333
            :|:|..|:|..|::::|::.:.|||||||||:::..|.||:..::.||:|||.|.:.::||.|..
  Fly   263 MHISHKPKPLPEDIKQFIEGSPHGVIYFSMGSNVKSKDLPQETRDTLLKTFAKLKQRVLWKFEDD 327

  Fly   334 YMPDKSDNVYVVEQAPQRHILNHPNVRLFITNGGLLSVIEAVDSGVPMLGLPMFFDQFGNMRWVQ 398
            .||.|..||.:.:..||..||.||||:|||::|||||..|:|..|.|:||||.|:||..|::..|
  Fly   328 DMPGKPANVLIKKWYPQPDILAHPNVKLFISHGGLLSSTESVYFGKPILGLPCFYDQHMNVQRAQ 392

  Fly   399 LSGMAEVMDINSLNKDTLTETIKHMLANNSYYLKAKEISQFFKDRPMSPLDTAVWWTEYALRNRN 463
            ..|....:|:|:|.::.|.:.|:.:|.:.||...:..||:.::|:|.|.:|.|||||||.:|:..
  Fly   393 RVGFGLGLDLNNLKQEDLEKAIQTLLTDPSYAKASLAISERYRDQPQSAVDRAVWWTEYVIRHNG 457

  Fly   464 ITRMRLNLEEIPLIEYYRIDS---ILAFSLRFGLVAASL 499
            ...:|....::..|:...:|:   |||..|...|:..:|
  Fly   458 APHLRATSRDLNFIQLNSLDTLAVILAVPLLLALLIVTL 496

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303B1	NP_651153.1	egt	21..462	CDD:223071	153/452 (34%)
Ugt303B1	NP_651153.1	UDPGT	41..511	CDD:278624	157/474 (33%)
Ugt35C1	NP_001097744.1	egt	1..470	CDD:223071	154/466 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	76	1.000	Domainoid score	I3136
eggNOG	1	0.900	-	-		E33208_3BDT1
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	89	1.000	Inparanoid score	I2281
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D45181at50557
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		otm14789
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	1	1.100	-	-	P	PTHR48043
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
	10	9.870