DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt303B1 and ugt2a1

DIOPT Version :9

Sequence 1:	NP_651153.1	Gene:	Ugt303B1 / 42775	FlyBaseID:	FBgn0039086	Length:	519	Species:	Drosophila melanogaster
Sequence 2:	XP_031759199.1	Gene:	ugt2a1 / 447975	XenbaseID:	XB-GENE-954008	Length:	735	Species:	Xenopus tropicalis

Alignment Length:	554	Identity:	133/554 - (24%)
Similarity:	240/554 - (43%)	Gaps:	90/554 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 LRYCWLTLSLCLLLQ-HDRAQAANILGIFPYRHISPFFVMQPLVRTLATRGHNVTLIT------- 59
            :.|.:..|...||.| |.....:.:|      ..|.:..::.::..||.:||.||.:.
Frog   212 IHYLFQDLLFALLFQWHWDEYYSEVL------DASHWLNLRLILEELAHKGHEVTALVHSANMLI 270

  Fly    60 -------------PIGMPND-------------IEGVRHIRVAQLNERIKEMLESDQVLDFMINK 98
                         |:....:             |.||.::...:|.|.:|..:.|...|.   ..
Frog   271 DHNLPSALKAEVFPVAFTKETFLTLQRDFFNFWIYGVHNMSYWELYEHLKVAVASSLKLQ---RD 332

  Fly    99 WTESALTAKALFNASNDILSDPGVQRMLHDKSESFDLIIMEPSS-----LDALYGLVEFYNATL- 157
            ..:..|..|.|               |...:::.||:::.:|.:     :....|:...|:...
Frog   333 TCDGVLKNKEL---------------MYKLQNQKFDIVVADPVAPCGELIAESLGVPFVYSFRFS 382

  Fly   158 MGLSSIRINWHTYELAGN-PAPSIYEPISPVGFSLETSLFSRVYNWIHIMEEKLVNYLILRPAQL 221
            ||.|..|       |.|. |:|..|.|.:...||.:.|...|:.|.:....:.|:..|:.:....
Frog   383 MGNSLER-------LCGQLPSPFSYVPGAMTAFSDKMSFGQRLANTVLYAFQDLIFSLVFQKNWD 440

  Fly   222 HLFQKFFGYSAQKMNELRSRFSLMLINSHYSMGKVRANAPNIIEVGGLHLSEPPEPSDEELQKFL 286
            :.:.:..|..| |:.|:..:..:.||.:::.....|...||...|||||.: |.:|..||::|.:
Frog   441 NYYSEILGRPA-KVCEIMGKAEIWLIRTYWDFEYPRPILPNFKFVGGLHCA-PAKPLPEEIEKVV 503

  Fly   287 DKA-DHGVIYFSMGNDILIKFLPENIQELLLQTFATLNESIIWKSELLYMPDKSD----NVYVVE 346
            :.: :||::.||||:  :||........::....:.|.:.::|:    |...|.|    |....:
Frog   504 ESSGEHGIVVFSMGS--MIKNFSNERTNIIAAALSQLPQKVLWR----YSGKKPDALGENTITYD 562

  Fly   347 QAPQRHILNHPNVRLFITNGGLLSVIEAVDSGVPMLGLPMFFDQFGNMRWVQLSGMAEVMDINSL 411
            ..||..:|.||..:.|||:||...:.||:..|||::|:|:|.:|..|:..::..|||.::|.|.:
Frog   563 WIPQNDLLGHPKTKAFITHGGTNGIYEAIYHGVPIVGIPLFAEQPDNIVHMKSKGMAIMLDFNKM 627

  Fly   412 NKDTLTETIKHMLANNSYYLKAKEISQFFKDRPMSPLDTAVWWTEYALRNRNITRMRLNLEEIPL 476
            ....|.:.:..::.|.:|...|..:|:...|:|:.|||:||:|.|:.:|::....:|....|:..
Frog   628 GTQDLLDAVNTVINNPTYKENAMRLSRIHHDQPVKPLDSAVFWIEFVMRHKGAKHLRPASHELTW 692

  Fly   477 IEYYRIDSILAFSLRFGLVAASLIFLVYTLFLKY 510
            .:|:.:|.|     .|..|...|.|.:...||.:
Frog   693 YQYHCLDVI-----GFMFVCLFLFFYITITFLTF 721

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303B1	NP_651153.1	egt	21..462	CDD:223071	116/485 (24%)
Ugt303B1	NP_651153.1	UDPGT	41..511	CDD:278624	125/515 (24%)
ugt2a1	XP_031759199.1	UDPGT	238..733	CDD:278624	126/522 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000