DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt303B1 and Ugt301D1

DIOPT Version :9

Sequence 1:	NP_651153.1	Gene:	Ugt303B1 / 42775	FlyBaseID:	FBgn0039086	Length:	519	Species:	Drosophila melanogaster
Sequence 2:	NP_001246079.1	Gene:	Ugt301D1 / 35105	FlyBaseID:	FBgn0032684	Length:	530	Species:	Drosophila melanogaster

Alignment Length:	550	Identity:	162/550 - (29%)
Similarity:	260/550 - (47%)	Gaps:	73/550 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MRLRY-CWLTLSLCLLLQHDRAQAANILGIFPYRHISPFFVMQPLVRTLATRGHNVTLIT--PIG 62
            |:|:: ||:.:.|..||:.........:|.||..  |.:..::.....|..:||:||.:.  |..
  Fly     3 MQLQWKCWMLIFLIGLLEFGAGSRILFMGPFPAP--SHWLWLEHFQNDLLRQGHHVTSVNNHPTK 65

  Fly    63 MPNDIEGVRHIRVAQLNERI------------KEMLESDQ-VLDFMINK----WTESALTAKALF 110
            .|::          .|.|.|            ||.:.|.| |.||  |.    ||...:|.:..|
  Fly    66 HPHE----------NLTEIIISPSFDIPKHFPKENIFSMQFVSDF--NNLELWWTIGLMTTEHAF 118

  Fly   111 NASNDILSDPGVQRMLHDKSESFDLIIMEPSSLDALYGLVEFYNATLMGLSSIRINWHTYELAGN 175
                   .||.|::::..|.:.:||:|:|....:|.....:.:|..::.:.       |...|.|
  Fly   119 -------KDPKVKKLIESKDDHYDLVIIEQFFHEAFLMFGKRFNCPVVTIG-------TMGYADN 169

  Fly   176 --PAPSIYEPISPVGFSL-----ETSLFSRVYNWIHIMEEKLVNYLILRPAQLHLFQKFFGYSAQ 233
              .|..|..|.|.:...|     ..:...|.||....:.:.::...:..|....|.:|:|..|.:
  Fly   170 IDHAMGILTPWSLIPHLLLSHTDRMTFGQRAYNAYLSLYDAVMRRWVYLPKMQKLAEKYFQGSIE 234

  Fly   234 ----KMNELRSRFSLMLINSHYSMGKVRANAPNIIEVGGLHLSEPPE-PSDEELQKFLDKADHGV 293
                .:.:|....||:|||:|.|:...|.:.|.:|:|||.|:.:|.: |:|  ||.|||.|.:||
  Fly   235 GPLPNVLDLERNISLVLINAHRSIDLPRPSMPGLIDVGGAHIQKPKQLPTD--LQNFLDNATYGV 297

  Fly   294 IYFSMGNDILIKFLPENIQELLLQTFATLNESIIWKSELLYMPDKSDNVYVVEQAPQRHILNHPN 358
            ||||||:.:....||:....|:|:.|..|.:.:|||.|...:.|...||.:.:..||..||.|||
  Fly   298 IYFSMGSYVKSTDLPQEKTALILKAFGQLKQQVIWKFENDSIGDLPSNVMIKKWMPQNDILAHPN 362

  Fly   359 VRLFITNGGLLSVIEAVDSGVPMLGLPMFFDQFGNMRWVQLSGMAEVMDINSLNKDTLTETIKHM 423
            |:||||:||:....|.:..|||||.:|::.||..|.......|.|..:..:.|..|.|...|:.:
  Fly   363 VKLFITHGGIFGTQEGIYWGVPMLCVPLYGDQHRNTIKSVREGYARSLVFSKLTTDDLVRNIETL 427

  Fly   424 LANNSYYLKAKEISQFFKDRPMSPLDTAVWWTEYALRNRNITRMRLNLEEIPLIEYYRIDSILAF 488
            :.:..|...|.|:||.|:|.|:.|||.|.:|.||.:|:|....::.:...|||.:|..:|
  Fly   428 INDPQYKRSALEVSQRFRDNPIHPLDEATFWIEYIIRHRGARHLKSHGAFIPLHQYLLLD----- 487

  Fly   489 SLRFGLVAASLIFLVYTLFLKYRIRLRRLH 518
                 ::...|:.....::|.:|: :||:|
  Fly   488 -----VLGCLLLGAFLAIWLPWRM-IRRVH 511

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303B1	NP_651153.1	egt	21..462	CDD:223071	143/471 (30%)
Ugt303B1	NP_651153.1	UDPGT	41..511	CDD:278624	147/500 (29%)
Ugt301D1	NP_001246079.1	egt	12..483	CDD:223071	150/500 (30%)
Ugt301D1	NP_001246079.1	UDPGT	37..483	CDD:278624	144/473 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	76	1.000	Domainoid score	I3136
eggNOG	1	0.900	-	-		E33208_3BDT1
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	89	1.000	Inparanoid score	I2281
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		otm14789
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	1	1.100	-	-	P	PTHR48043
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
	9	8.860