Protein Alignment Ugt303B1 and Ugt2a3

DIOPT Version :10

• Sequence 1: NP_651153.1
• Gene: Ugt303B1 / 42775
• FlyBaseID: FBgn0039086
• Length: 519
• Species: Drosophila melanogaster
• Sequence 2: NP_001129341.1
• Gene: Ugt2a3 / 289533
• RGDID: 1308444
• Length: 534
• Species: Rattus norvegicus
• Alignment Length: 569
• Identity: 142/569 - (24%)
• Similarity: 252/569 - (44%)
• Gaps: 115/569 - (20%)

  Fly     3 LRYCWLTLSLCLLLQHDRAQAANILGIFPYRHISPFFVMQPLVRTLATRGHNVTL---------- 57
            |:.||....:|          :.:| ::|. .:|.:..::.::..||.|||.||:
  Rat    13 LQLCWSGCGIC----------SKVL-VWPC-DMSHWLNLKTILEELAARGHEVTVLKYPSIIIDQ 65

  Fly    58 --ITPIGMPNDIEGVRHIRVAQ--LNERIKEMLESDQVLDFMIN------KWTESALTAKALF-- 110
              :||:...| |..:....||:  |||          :::..:|      .| |:|.|.:..|
  Rat    66 SKLTPLQFEN-IPVLYETEVAENHLNE----------IVNLAVNVIPNLSLW-EAARTLQDFFLQ 118

  Fly   111 ------NASNDILSDPGVQRMLHDKSESFDLIIMEP----SSLDALYGLVEFYNATL---MGLSS 162
                  :.....|.:..:...|.|  ..:|:::::|    ..|.|....:.|.| ||   ||.|
  Rat   119 LTGNFEDLCRSTLYNQTLMNKLRD--AKYDVMVLDPVIPCGELVAEVLQIPFVN-TLRFSMGYS- 179

  Fly   163 IRINWHTYELAGN-PAPSIYEPISPVGFSLETSLFSRVYN---------WIHIME----EKLVNY 213
                  ..:..|. |.|..|.|:.....:...:...||.|         |:...:    ::..:.
  Rat   180 ------MEKYCGQLPVPLSYVPVVMGELTDHMTFTERVKNMMLSLFFEFWLQQYDFAFWDQFYSK 238

  Fly   214 LILRPAQLHLFQKFFGYSAQKMNELRSRFSLMLINSHYSMGKVRANAPNIIEVGGLHLSEPPEPS 278
            .:.||.   .|.|..|           :..:.||.:::.:...|...||...||||| .:|.:|.
  Rat   239 TLGRPT---TFCKTVG-----------KAEIWLIRTYWDIEFPRPYLPNFEFVGGLH-CKPAKPL 288

  Fly   279 DEELQKFLDKA-DHGVIYFSMGNDILIKFLPENIQELLLQTFATLNESIIWKSELLYMPDK---- 338
            .:||::|:..: :|||:.||:|:  :||.|.|....|:....|.:.:.::|:    |...|
  Rat   289 PKELEEFVQSSGEHGVVVFSLGS--MIKNLTEEKANLIASALAQIPQKVLWR----YSGKKPATL 347

  Fly   339 SDNVYVVEQAPQRHILNHPNVRLFITNGGLLSVIEAVDSGVPMLGLPMFFDQFGNMRWVQLSGMA 403
            ..|..::...||..:|.||..|.|||:||...:.||:..||||:|:|||.||..|:..::..|.|
  Rat   348 GPNTRILNWIPQNDLLGHPKTRAFITHGGTNGIYEAIYHGVPMVGIPMFGDQPYNIAHMEAKGAA 412

  Fly   404 EVMDINSLNKDTLTETIKHMLANNSYYLKAKEISQFFKDRPMSPLDTAVWWTEYALRNRNITRMR 468
            ..:.||::....|...::.::...||...|..:|:...|:|:.|||.||:|.|:.:|::....:|
  Rat   413 VKVAINTMTSADLLSALRAVINEPSYKENAMRLSRVHHDQPVKPLDRAVFWIEFVMRHKGAKHLR 477

  Fly   469 LNLEEIPLIEYYRIDSILAFSLRFGLVAASLIFLV--YTLFLKYRIRLR 515
            :...::...:|:.:| ::.|.|   :...:|.|::  .:||:..:..||
  Rat   478 VAAHDLSWFQYHSLD-VIGFLL---VCVVTLTFVITKCSLFMCRKCCLR 522

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303B1	NP_651153.1	Glycosyltransferase_GTB-type	21..462	CDD:471961	127/494 (26%)
Ugt2a3	NP_001129341.1	UDPGT	25..519	CDD:278624	136/542 (25%)