Protein Alignment Ugt303B1 and Ugt1a1

DIOPT Version :10

• Sequence 1: NP_651153.1
• Gene: Ugt303B1 / 42775
• FlyBaseID: FBgn0039086
• Length: 519
• Species: Drosophila melanogaster
• Sequence 2: NP_036815.1
• Gene: Ugt1a1 / 24861
• RGDID: 3935
• Length: 535
• Species: Rattus norvegicus
• Alignment Length: 539
• Identity: 129/539 - (23%)
• Similarity: 236/539 - (43%)
• Gaps: 78/539 - (14%)

  Fly     6 CWLTLSLCLLL--QHDRAQAANILGIFPYRHISPFFVMQPLVRTLATRGHNVTLITPIGMPNDIE 68
            |.|.|..||||  ....|..|..|.:.|... |.:..|..:::.|..:||.|.:|.|....:..|
  Rat     9 CSLLLLPCLLLCVLGPSASHAGKLLVIPIDG-SHWLSMLGVIQQLQQKGHEVVVIAPEASIHIKE 72

  Fly    69 G----VRHIRVAQLNERI--------KEMLESDQVLDFMINKWTESALTAKALFNASNDILSDPG 121
            |    :|...|...||.:        :.:.:.|..|..::..:.:....:..|.:         |
  Rat    73 GSFYTMRKYPVPFQNENVTAAFVELGRSVFDQDPFLLRVVKTYNKVKRDSSMLLS---------G 128

  Fly   122 VQRMLHD-------KSESFDLIIMEP-----------SSLDALYGLVEFYNATLMGLSSIRINWH 168
            ...:||:       :...||.::.:|           .||.|:|    |.||....|.
  Rat   129 CSHLLHNAEFMASLEQSHFDALLTDPFLPCGSIVAQYLSLPAVY----FLNALPCSLD------- 182

  Fly   169 TYELAGNPAPSIYEPISPVGFSLETSLFSRVYNWIHIMEEKLVNYLILRPAQLHLFQKFFGYSA- 232
             .|....|||..|.|.|....:...:...||.|.|..:.|..:..::..|         :|..|
  Rat   183 -LEATQCPAPLSYVPKSLSSNTDRMNFLQRVKNMIIALTENFLCRVVYSP---------YGSLAT 237

  Fly   233 ---QK---MNELRSRFSLMLINSHYSMGKVRANAPNIIEVGGLHLSEPPEPSDEELQKFLD-KAD 290
               ||   :.:|.|..|:.|:.:.:.....|...||::.:||::..:....| :|.:.::: ..:
  Rat   238 EILQKEVTVKDLLSPASIWLMRNDFVKDYPRPIMPNMVFIGGINCLQKKALS-QEFEAYVNASGE 301

  Fly   291 HGVIYFSMGNDILIKFLPENIQELLLQTFATLNESIIWKSELLYMPDKSDNVYVVEQAPQRHILN 355
            ||::.||:|:  ::..:||.....:.:....:.::::|:.......:.:.|..:|:..||..:|.
  Rat   302 HGIVVFSLGS--MVSEIPEKKAMEIAEALGRIPQTVLWRYTGTRPSNLAKNTILVKWLPQNDLLG 364

  Fly   356 HPNVRLFITNGGLLSVIEAVDSGVPMLGLPMFFDQFGNMRWVQLSGMAEVMDINSLNKDTLTETI 420
            ||..|.|||:.|...:.|.:.:||||:.:|:|.||..|.:.::..|....:::..:..|.|...:
  Rat   365 HPKARAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENAL 429

  Fly   421 KHMLANNSYYLKAKEISQFFKDRPMSPLDTAVWWTEYALRNRNITRMRLNLEEIPLIEYYRIDSI 485
            |.::.|.||......:|...||||:.|||.||:|.||.:|::....:|....::...:|:.:| :
  Rat   430 KTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLD-V 493

  Fly   486 LAFSLRFGLVAASLIFLVY 504
            :.|.|   .:..:::|:||
  Rat   494 IGFLL---AIVLTVVFIVY 509

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303B1	NP_651153.1	Glycosyltransferase_GTB-type	21..462	CDD:471961	114/478 (24%)
Ugt1a1	NP_036815.1	UDPGT	30..526	CDD:278624	120/518 (23%)