DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt303B1 and ugt-3

DIOPT Version :9

Sequence 1:	NP_651153.1	Gene:	Ugt303B1 / 42775	FlyBaseID:	FBgn0039086	Length:	519	Species:	Drosophila melanogaster
Sequence 2:	NP_506203.2	Gene:	ugt-3 / 191174	WormBaseID:	WBGene00013903	Length:	529	Species:	Caenorhabditis elegans

Alignment Length:	545	Identity:	133/545 - (24%)
Similarity:	222/545 - (40%)	Gaps:	80/545 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 ILGIFP------YRHISPFF------VMQPLVRTLATRGHNVTLITPI-----------GMPNDI 67
            :|..||      |..|||.|      .|..:...||..||||||..||           ..|| |
Worm     6 LLAFFPVAFGFNYLIISPVFGYSHMKFMGRIADILADAGHNVTLFQPIIYDYYAHKKIVKNPN-I 69

  Fly    68 EGVRHIRVAQLNERIKEMLESDQVLDFM------INKWTESALTAKALFNASNDILSDPGVQRML 126
            |.:.:    :::|..|.......|..|.      .|..:.:.:|::.|:.....|     .::||
Worm    70 EVINY----EVDEEEKAAASEASVFKFFWKAKGSKNPISSAKITSEKLYKEFEHI-----CRKML 125

  Fly   127 HDK-------SESFDLIIMEPSSLDALY--------GLVEFYNATLMGLSSIRINWHTYELAGNP 176
            .||       |::||..|.|......||        ..:..|:....|.:|..:        |.|
Worm   126 LDKELHRWILSKNFDSHISEAFDFCGLYLGDFLKLKSPIPLYSGVRCGAASYAV--------GEP 182

  Fly   177 APSIYEPISPVGFSLETSLFSRVYNWIHIMEEKLVNYLILRPAQLHLFQKFFGYSAQKMNELRSR 241
            .|..|.|.....:..::|...|:.:.:.:..... .:.||...|.....:..|.:.:...|:...
Worm   183 IPLNYLPTEGSNYGKKSSAIDRLSDMLGLTGYHF-QFGILFDKQYDQAYRLTGGNVRTWQEILQS 246

  Fly   242 FSLMLINSHYSMGKVRANAPNIIEVGGLHL-SEPPEPSDEELQKFLDKADHGVIYFSMGNDILIK 305
            .:..|.||:..:.........:|::||..: |......|||..|.|...:: .|..|.|..|...
Worm   247 STFFLTNSNPYLSFSTPTISKVIQIGGFTIESFKTTTLDEEFNKILSLRNN-TILVSFGTVIQSS 310

  Fly   306 FLPENIQELLLQTFATL-NESIIWKSELLYMPDK------SDNVYVVEQAPQRHILNHPNVRLFI 363
            .:|::.:..|::.|..: :.:.|||.|   ..||      |:||.:.:..||..:|....:.||:
Worm   311 DMPDDFKTGLIEAFRRMPDATFIWKYE---EDDKTLKNKLSENVVLSKWIPQPALLADSRLDLFV 372

  Fly   364 TNGGLLSVIEAVDSGVPMLGLPMFFDQFGNMRWVQLSGMAEVMD-INSLNKDTLTETIKHMLANN 427
            |:|||.|.:|...:||..:.:|:|.||..|...:...|.|.|.| .:.::...|.|||:.:|.|:
Worm   373 THGGLGSTMEVGYAGVSSIMVPVFSDQGVNAEMLARHGGAIVYDKFDLVDSKKLMETIQMILNNS 437

  Fly   428 SYYLKAKEISQFFKDRPMSPLDTAVWWTEYALRNRNITRMRLNLEEIPLIEYYRIDSILAFSLRF 492
            .|...:|.:|....::||.|....:...|:|.|...:..:.....:...||:|.:||:.......
Worm   438 DYRKNSKRLSDILHNQPMDPKQVLLNHCEFAARFAQVDNLEPYANKYNFIEFYCLDSLALVVCTI 502

  Fly   493 GLVA----ASLIFLVYTLFLKYRIR 513
            .:||    ..|.|:|.::..|.:::
Worm   503 SVVALVMFKILSFVVNSVIEKLKLK 527

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303B1	NP_651153.1	egt	21..462	CDD:223071	122/488 (25%)
Ugt303B1	NP_651153.1	UDPGT	41..511	CDD:278624	125/514 (24%)
ugt-3	NP_506203.2	egt	1..457	CDD:223071	118/473 (25%)
ugt-3	NP_506203.2	UDPGT	27..525	CDD:278624	125/520 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.900