DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt303B1 and ugt-55

DIOPT Version :9

Sequence 1:	NP_651153.1	Gene:	Ugt303B1 / 42775	FlyBaseID:	FBgn0039086	Length:	519	Species:	Drosophila melanogaster
Sequence 2:	NP_506073.2	Gene:	ugt-55 / 188072	WormBaseID:	WBGene00011452	Length:	512	Species:	Caenorhabditis elegans

Alignment Length:	563	Identity:	123/563 - (21%)
Similarity:	206/563 - (36%)	Gaps:	152/563 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 LRYCWLTLSLCLLLQHDR---------AQAANILGIFPYRHISPFFVMQPLVRTLATRGHNVTLI 58
            |.|....|||.:|:...|         |..||:||                     .|||||.::
Worm    14 LNYGTPCLSLRILVYSPRMIPSHVAFVANIANLLG---------------------QRGHNVVVV 57

  Fly    59 -----TPIGMPNDIEGVRHIRVAQLNERIKEMLESDQVLDFMINKWTESALTAKALFNASND--- 115
                 :.|....|::.:..:...:.:..:.::| :||.:.  ||.|        ::.|...:
Worm    58 DNVLRSDISNKLDLKVIEKVVKVETSANVAKLL-ADQSIP--INFW--------SMRNEPEEQKK 111

  Fly   116 ILSDPGV-----QRMLHDKSESFDLIIMEPSSLDALYGLVEFYNATLMGLSSIRINWHTYELAG- 174
            ::...|:     .:.|..|.|:   :..|...|:..:|:.|.::...:|:         :|..|
Worm   112 VMKQLGIIFLEQCKYLVSKEET---VFNELKHLEFDFGIHEVFDICGIGI---------FEKLGI 164

  Fly   175 ---------------NPAPSIYEPISPVGFSLETSLFSRVYNWIHIMEEKLVNYLILRPAQLH-L 223
                           |.|..|...:.      :.|:.|...|.|..       |.|.|..:.| .
Worm   165 RKSVILSSTGMRDIVNEALGISSQLQ------DASILSDYGNSIPF-------YGIRRNLKFHSA 216

  Fly   224 FQKFFGYSAQKMNELRS---------RFS-LMLINSHYSMGKVRANAPNIIEVGGLHLSEPPEPS 278
            ::.||...::.:..|..         ||| ||.:|:|......|..:..:.|:||:....|....
Worm   217 WRNFFEVQSKTLEPLFETTSSFENLLRFSNLMFLNTHELADAHRPWSRRVHEIGGISFKFPMPLK 281

  Fly   279 DEELQKFLDKADHGVIYFSMGNDILIKFLPENIQELLLQTFATLNESI-IWKSEL---LYMPDKS 339
            :|.:..|  ...:.:|..|.|.......:||..:..|:.||....:.: |||.|.   ....:|.
Worm   282 NEYINLF--NKYNSIILVSFGTTTPSFLMPEKYKNTLINTFQRFPDFLFIWKYEKDDEFTQKNKK 344

  Fly   340 DNVYVVEQAPQRHILNHPNVRLFITNGGLLSVIEAVDSGVPMLGLPMFFDQFGNMRWVQLSGMAE 404
            .||...:..||..:|....::||||:||..|::|...|....|..|:|.||..|.:....:|::.
Worm   345 GNVVFKKFLPQVDLLESRKIKLFITHGGQNSLLETFHSNTRTLITPLFGDQHRNAQIALENGLSH 409

  Fly   405 VMDINSLNKDTLTETIKHMLANNS-YYLKAKEISQFFKDRPMSPLDTAVWWTEYALRNRNITRMR 468
            |:             :|..|||.. .|...|:.::..|     .||..:......|:|...|...
Worm   410 VL-------------LKDQLANEELVYAAIKQGTESNK-----KLDDNLLKLSSNLKNAKQTSEN 456

  Fly   469 LNLEEI---------PL-IEYY-----------RIDSILAFSL 490
            |.|:.:         || .|:|           .:|||..|:|
Worm   457 LFLDTVESTYTDNLSPLNFEFYPKLYSSDQILLYLDSIAMFTL 499

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303B1	NP_651153.1	egt	21..462	CDD:223071	103/485 (21%)
Ugt303B1	NP_651153.1	UDPGT	41..511	CDD:278624	111/516 (22%)
ugt-55	NP_506073.2	UDPGT	35..>399	CDD:278624	90/422 (21%)
ugt-55	NP_506073.2	Glycosyltransferase_GTB_type	<247..>399	CDD:299143	43/153 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.900