DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt303B1 and ugt-13

DIOPT Version :9

Sequence 1:	NP_651153.1	Gene:	Ugt303B1 / 42775	FlyBaseID:	FBgn0039086	Length:	519	Species:	Drosophila melanogaster
Sequence 2:	NP_504317.2	Gene:	ugt-13 / 186766	WormBaseID:	WBGene00019232	Length:	532	Species:	Caenorhabditis elegans

Alignment Length:	546	Identity:	128/546 - (23%)
Similarity:	235/546 - (43%)	Gaps:	95/546 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 CLLLQHDRAQAANIL---GIFPYRHISPFFVMQPLVRTLATRGHNVTLITP--IGMPNDIEGV-- 70
            |||:..  ..:.|||   .||.:.|:....:|..::   |..||||||..|  |.:|| ::|:
Worm     9 CLLISF--VSSKNILIYDPIFGFSHVKFVSLMAEII---ANHGHNVTLFRPYHIALPN-VDGLVK 67

  Fly    71 -RHIRVAQ-LNERIKEMLESDQ-----------VLDFMINKWTESALTAKALFNASNDILSDPGV 122
             ::|::.. ..:...|:|.:::           :...::.....|.|.:..:...:..:|.|
Worm    68 NKNIQIIDYFPKHYDELLHAEKQTFPGFWNDPLISQPVLRSLVVSKLISGEMKRTATQLLQD--- 129

  Fly   123 QRMLHD-KSESFDLIIMEPSSLDALYGLVEFYNATLMG-LSSIRINWHTYELAGNPAPSIY--EP 183
            :|:|:: :|:.||::|.|...:..|| |....:...:. :.::|.....| |.|.|:...|  :|
Worm   130 ERVLNELRSKKFDVVISETFEITGLY-LAHIIDVPCIPMMPAVRYLDLGY-LLGQPSLIGYAQQP 192

  Fly   184 ISPV----GF-------------SLETSLFSRVYNWIHIMEEKLVNYLILRPAQLHLFQKFFGYS 231
            .|.:    ||             |.||       :|....:...:...|.||
Worm   193 GSKMAPEAGFLDRLNDVYQYFFMSCET-------DWTSQYQNDNIEAAIGRP------------- 237

  Fly   232 AQKMNELRSRFSLMLINSHYSMGKVRANAPNIIEVGGLHLS----EPPEPSDEELQKFLDKADHG 292
            .....:|.....:.::||:..:.........|::|||:.:.    :......||.:..|.:.|:.
Worm   238 LPNWKDLLRNSPIYILNSNPYLDFAVPTTATIVQVGGMTVDLKKMKNVAKLSEEYETILAERDYA 302

  Fly   293 VIYFSMGNDILIKFLPENIQELLLQTFATLNE-SIIWKSELLYMPDKSD---------NVYVVEQ 347
            |: .|.|:.|....:|:|.:..|::.|.:|:: :.|||.|      |.|         ||::.:.
Worm   303 VL-ISFGSVIRSFQMPDNFKVGLIKLFESLSDVTFIWKYE------KGDVEFQKRLPKNVHLKKW 360

  Fly   348 APQRHILNHPNVRLFITNGGLLSVIEAVDSGVPMLGLPMFFDQFGNMRWVQLSGMA-EVMDINSL 411
            .||..:|....|:||:|:|||.|..|...:|.|.|.:|:|.||..|...:...|.| .....:..
Worm   361 VPQPSLLADKRVKLFVTHGGLGSTTEVAYTGKPALMVPIFGDQPNNADMLARHGGAIAYSKFDLA 425

  Fly   412 NKDTLTETIKHMLANNSYYLKAKEISQFFKDRPMSPLDTAVWWTEYALRNRNITRMRLNLEEIPL 476
            |.:.|..|:|.|:.|..|..||:.:.....::|:.|.:..:...|:|::..|.......:.:..|
Worm   426 NGEKLANTVKDMVFNPKYKEKAELLFDVLSNQPIDPKENFIKHLEFAMKFPNHRSQVPAVNQAGL 490

  Fly   477 IEYYRIDSILAFSLRFGLVAASLIFL 502
            |..|.:| ::.|.:...|:::.|.|:
Worm   491 IAQYYLD-VIVFFVMISLISSYLSFV 515

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303B1	NP_651153.1	egt	21..462	CDD:223071	116/496 (23%)
Ugt303B1	NP_651153.1	UDPGT	41..511	CDD:278624	119/515 (23%)
ugt-13	NP_504317.2	egt	1..509	CDD:223071	126/538 (23%)
ugt-13	NP_504317.2	UDPGT	29..514	CDD:278624	119/521 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.810