DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt303B1 and ugt-42

DIOPT Version :9

Sequence 1:	NP_651153.1	Gene:	Ugt303B1 / 42775	FlyBaseID:	FBgn0039086	Length:	519	Species:	Drosophila melanogaster
Sequence 2:	NP_503278.2	Gene:	ugt-42 / 185168	WormBaseID:	WBGene00017959	Length:	527	Species:	Caenorhabditis elegans

Alignment Length:	540	Identity:	124/540 - (22%)
Similarity:	229/540 - (42%)	Gaps:	74/540 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 ANILGIFPYRHISPFF------VMQPLVRTLATRGHNVTLITPIGMPNDIEGVRHIRVAQLNERI 82
            :||.| |.|..:||.|      .|..|...|...|||||:::.| :.:....:.:.::.:....:
Worm    14 SNISG-FNYLVVSPAFGHSHSTFMGKLADALTEAGHNVTVLSII-VSSKFRNISYTKLTKDIVVV 76

  Fly    83 KEMLESDQVLDFMINK-----WTE-----SALTAKALFNASNDILSDPGVQ--------RMLHDK 129
            :...|.||..:.|.|.     ||:     ..:.:..:|..    :||.|.:        :|.:.|
Worm    77 ETTNEQDQQAENMENNDFSRYWTQEGTLLETIPSYLMFTK----MSDHGYETFRNHALPQMEYLK 137

  Fly   130 SE--SFDLIIMEPSSLDALYGLVEFYN-ATLMGLSSIRINWHTYELAGNPAPSIYEPISPVGFSL 191
            |.  .:|.:..| |.|.....:.|:.. ...:.::|:..::...||.|       ||:||...|.
Worm   138 SHRPRYDAVFFE-SYLHTGKAIQEYLEIPVFLPVTSLTHDYRLAELIG-------EPVSPSYLSG 194

  Fly   192 ETSLFSRVYNWIHIMEEKLVNYLILRPAQLHLFQKFFGYSAQKMNELRSRFSLMLINSHYSMGK- 255
            ..:.|..:.|:    :|:::|.|....||:.:       |:.....|:.....:|:.|.|....
Worm   195 YFTNFGNIMNF----QERVINTLSYYLAQILI-------SSPNWKTLQDPSKDLLVESEYYRAPY 248

  Fly   256 --VRANAPNI----------IEVGGLHLSE---PPEPSDEELQKFLDKADHGVIYFSMGNDILIK 305
              :.:| |.|          ||:||:.:..   ..|..||.....|.:..|.|: .|.|......
Worm   249 VFINSN-PYIDFPRPLLSKTIEIGGITVDADALKSEKVDETWNNILKRRPHNVL-ISFGTMFKSI 311

  Fly   306 FLPENIQELLLQTFATL-NESIIWK--SELLYMPDKSDNVYVVEQAPQRHILNHPNVRLFITNGG 367
            .:|::.:..:::...:. |.:.|||  ||.....:.::|:...:..||..:|....:..|.|:||
Worm   312 HMPDSYKNNMVKVMKSFKNVTFIWKYESEETSFANGAENIIFKKWTPQTALLADSRLSAFFTHGG 376

  Fly   368 LLSVIEAVDSGVPMLGLPMFFDQFGNMRWV-QLSGMAEVMDINSLNKDTLTETIKHMLANNSYYL 431
            |.||.|....|.|.|..|:|.||..|.:.: :.:|..|:...|..:.:||...:..:|.:.||..
Worm   377 LGSVNELSYLGKPALLCPLFADQVRNSKMLSRHNGSIEISKFNLESYNTLRSALHSILFDESYAE 441

  Fly   432 KAKEISQFFKDRPMSPLDTAVWWTEYALRNRNITRMRLNLEEIPLIEYYRIDSILAFSLRFGLVA 496
            .|:::::..:.:|..|.:..|...|:|.|......:..||..:....|:.:|.::..:....||.
Worm   442 NAEKLAKKLEFQPAKPKELFVRHAEFAARFGEQPALDCNLRTMGFATYHLLDVVVCLTSFVVLVI 506

  Fly   497 ASLIFLVYTLFLKYRIRLRR 516
            .||:.::..:.....|:::|
Worm   507 LSLVVIIRKIVQSLAIKMKR 526

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303B1	NP_651153.1	egt	21..462	CDD:223071	114/484 (24%)
Ugt303B1	NP_651153.1	UDPGT	41..511	CDD:278624	114/510 (22%)
ugt-42	NP_503278.2	Glycosyltransferase_GTB_type	14..501	CDD:299143	118/513 (23%)
ugt-42	NP_503278.2	UDPGT	22..495	CDD:278624	113/498 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.900