DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt303B1 and ugt-37

DIOPT Version :9

Sequence 1:	NP_651153.1	Gene:	Ugt303B1 / 42775	FlyBaseID:	FBgn0039086	Length:	519	Species:	Drosophila melanogaster
Sequence 2:	NP_504811.2	Gene:	ugt-37 / 184293	WormBaseID:	WBGene00017332	Length:	528	Species:	Caenorhabditis elegans

Alignment Length:	525	Identity:	131/525 - (24%)
Similarity:	230/525 - (43%)	Gaps:	89/525 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 IFPYRHISPFFVMQPLVRTLATRGHNVTLITP-----IGMPNDIEGVRHIRVAQLNERIKEMLES 88
            :|.:.| :.||.  .:..||:..|||||..||     ....|.::..:|:...:.:|:::..  .
Worm    25 LFGHSH-TTFFA--KIADTLSEAGHNVTFFTPTIIRKFSKINYVKHTKHVIHLEPSEKLERY--G 84

  Fly    89 DQVLDFMINK-WTESALTAK-----ALFN-----------ASNDILSDPGVQRMLHDKSESFDLI 136
            :|:.|..|:: ||:.:..|:     .|||           .:.|:|.:.        |...||::
Worm    85 NQMEDVDISRFWTDDSSMAEMFPMIKLFNEMFAEQAFVLGQNLDVLDEL--------KEMKFDVM 141

  Fly   137 IMEPSSLDALYGLVEFYN-ATLMGLSSIRINWHTYELAGNPAPSIYEPISPVGFSLETSLFSRVY 200
            |.|..: :..|.|:|:.. .|.:..||:..:       .|...||.||..|....|..|.|:...
Worm   142 IFERFA-ECAYPLLEYLEIETFIPSSSLLFD-------PNLLISIGEPRIPSTVPLPMSKFTDKM 198

  Fly   201 NWIHIMEEKLVNYLI------LRPAQLHLFQKFF-GYSA---QKMNELRSRFSLMLINSHYSMGK 255
            .    |.|:|:|.:.      |.|.  |.|:.|. .|.|   |||..|.   |.:|.||:..:..
Worm   199 T----MTERLLNAIAVPIFHSLLPT--HEFKSFRPPYQAIDIQKMEHLS---SFILSNSNPYIDY 254

  Fly   256 VRANAPNIIEVGGLHLSEPP---EPSDEELQKFLDKADHGVIYFSMGNDILIKFLPENIQELLLQ 317
            .|......:::||:.:....   ...:||..:.||.... .|..|.|:.:|.|.:|...:::|.:
Worm   255 PRPTLEKNVQIGGISVDVENLKIHKVNEEWDRILDMRQK-TILVSFGSVMLSKDMPVENKKILAK 318

  Fly   318 TFATLNE-SIIWKSEL----LYMPDKSDNVYVVEQAPQRHILNHPNVRLFITNGGLLSVIEAVDS 377
            |.....| :.|||.|.    |: ..:::|::.....||..:|....:..|.|:.||.||.|....
Worm   319 TMKQFPEVTFIWKYEFNDTDLF-ASETENIHFSSWVPQTALLADRRLTAFFTHAGLGSVNEVSYL 382

  Fly   378 GVPMLGLPMFFDQFGNMRWV-QLSGMAEVMDINSLNKDTLTETIKHMLANNSYYLKAKEISQFFK 441
            |.|.:..|:|.||..|.:.: :.:|..|:...:..|.:.:.:|::.:|.::||.|.|::::....
Worm   383 GKPSIMCPIFADQMRNAKMLARHNGSIEISKYDLGNGEKIEKTLRTILFDDSYRLSAEKLAHQLA 447

  Fly   442 DRPMSPLDTAVWWTEYALRNRNITRMRLNLEEIPLIEYYRIDSILAFSLRFGLVAASLIF----L 502
            ::|:.|.:..:...|:|.:...:..:.....::..:||:.||           |||.|||    :
Worm   448 NQPVKPKELLLRHAEFAAQFGRLPSLDPYSRQLSFVEYFLID-----------VAAILIFSSLLI 501

  Fly   503 VYTLF 507
            |..||
Worm   502 VVVLF 506

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303B1	NP_651153.1	egt	21..462	CDD:223071	118/474 (25%)
Ugt303B1	NP_651153.1	UDPGT	41..511	CDD:278624	127/513 (25%)
ugt-37	NP_504811.2	Glycosyltransferase_GTB_type	1..504	CDD:299143	129/521 (25%)
ugt-37	NP_504811.2	UDPGT	37..510	CDD:278624	127/510 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.810