DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt303B1 and ugt-21

DIOPT Version :9

Sequence 1:	NP_651153.1	Gene:	Ugt303B1 / 42775	FlyBaseID:	FBgn0039086	Length:	519	Species:	Drosophila melanogaster
Sequence 2:	NP_001293944.1	Gene:	ugt-21 / 183141	WormBaseID:	WBGene00007885	Length:	534	Species:	Caenorhabditis elegans

Alignment Length:	529	Identity:	129/529 - (24%)
Similarity:	234/529 - (44%)	Gaps:	75/529 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 IFPYRHISPFFVMQPLVRTLATRGHNVTLITPIGMPN-----DIEGVRHIRVAQLNERIKEMLES 88
            :|.:.|:.   |:......|...|:|||::.|:...|     .::..::....:....::|:: |
Worm    28 LFGHSHVK---VLAAAADILTDAGNNVTVLMPVFDNNLRNKTSLKSTKNTIFVEAGPNVEELM-S 88

  Fly    89 DQVLDFMINKWTESALTAKALFNASND-----------ILSDPGVQRMLHDKSESFDLIIMEPSS 142
            | :..|:.|.|.|.......:..|:.|           ::|:||:...|  |:|::||.|.||
Worm    89 D-MRQFLANAWKEDTGNPITMMKAAQDMGTAFAEQCTKVISEPGLLEKL--KAENYDLAITEP-- 148

  Fly   143 LDAL-YGLVEFYN--ATLMGLSSIRINWHTYELAGNPAPSIYEPISPVGFSLETSLFSRVYNWIH 204
            .|.. |.|.|..|  |.:..|::.|.: |..::.|.|..|.|.|    |...||.  .|:
Worm   149 FDTCGYALFEAINIRAHVAILTANRFD-HVTDVIGQPIASSYVP----GTQSETG--DRM----- 201

  Fly   205 IMEEKLVNYLILRPAQLHLFQKFFG------YSAQK--------MNELRSRFSLMLINSHYSMGK 255
            .|.|:|.||.     |..:...||.      :.|.|        ...:....|.:|.|....:..
Worm   202 TMGERLGNYF-----QFLVGSYFFSLIGDRDFEAAKSVVPITRSWRAILPEASFILTNQIPLLDF 261

  Fly   256 VRANAPNIIEVGGLHLSEPPE--PSDEELQKFLDKADHGVIYFSMGNDILIKFLPENIQELLLQT 318
            .......|:.:|||.:....:  ..||:..|.|....:.| :.|.|::.....:|:..:..|...
Worm   262 PAPTFDKIVPIGGLSVKTEKKNLKLDEKWSKILGIRKNNV-FISFGSNAKSVDMPDEFKNSLADV 325

  Fly   319 FATL-NESIIWKSELLYMP--DKSDNVYVVEQAPQRHILNHPNVRLFITNGGLLSVIEAVDSGVP 380
            |.:: :.:.|||.|....|  :..|||::.:..||..:|..|.:.:|:|:|||.||.|....|.|
Worm   326 FKSMPDTTFIWKYENTSDPIVNHLDNVHLGDWLPQNELLADPRLSVFVTHGGLGSVTELAMMGTP 390

  Fly   381 MLGLPMFFDQFGNMRWVQLSGMAEVMDINSLNKDT--LTETIKHMLANNSYYLKAKEISQFFKDR 443
            .:.:|:|.||..|.:.::..|.|.|::.|:| .||  :.||::.::.:..|...:|.:::...::
Worm   391 AVMIPLFADQGRNAQMLKRHGGAVVIEKNNL-ADTHFMKETLEKVIKDPKYLENSKRLAEMLTNQ 454

  Fly   444 PMSPLDTAVWWTEYALRNRNITRMRLNLEEIPLIEYYRIDSILAFSLRFGLVAASLIFLVYTLFL 508
            |.:|.:|.:.:.|:|.|...:..:.........|||:.:|.|       .::|...:|.:|..::
Worm   455 PTNPKETLIKYVEFAARFGKLPSLDNYGRHQSYIEYFFLDII-------AILAVISLFSLYISYI 512

  Fly   509 KYRIRLRRL 517
            ..|..:|::
Worm   513 ILRAVIRKI 521

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303B1	NP_651153.1	egt	21..462	CDD:223071	119/472 (25%)
Ugt303B1	NP_651153.1	UDPGT	41..511	CDD:278624	124/509 (24%)
ugt-21	NP_001293944.1	UDPGT	32..526	CDD:278624	128/525 (24%)
ugt-21	NP_001293944.1	egt	<263..504	CDD:223071	64/249 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	172	1.000	Inparanoid score	I2735
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.860