DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt303B1 and ugt-4

DIOPT Version :9

Sequence 1:	NP_651153.1	Gene:	Ugt303B1 / 42775	FlyBaseID:	FBgn0039086	Length:	519	Species:	Drosophila melanogaster
Sequence 2:	NP_001041203.1	Gene:	ugt-4 / 179754	WormBaseID:	WBGene00013905	Length:	535	Species:	Caenorhabditis elegans

Alignment Length:	559	Identity:	128/559 - (22%)
Similarity:	231/559 - (41%)	Gaps:	103/559 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 LCLLL-----QHDRAQAANILG-IFPYRHISPFFVMQPLVRTLATRGHNVT-------------- 56
            ||:||     .|..:....::. ::.|.|:.   .|..:...||..||.||
Worm     5 LCVLLFSVLVSHVESYKFLVISPVYGYSHMK---FMAIIANQLADEGHQVTYFQPFVIEAYLDHK 66

  Fly    57 -----LITPIGMPNDIEGVRHI------RVAQLNERIKEMLESDQVLD---FMINKWTESALTAK 107
                 ||..|...:|.||.|||      ..|..:.:.:..|.:  |.|   |:::.|.
Worm    67 LLNNSLIDVINYWHDEEGRRHIPPSNDLHDAWYSSKYQSALSA--VFDMPQFLVSAWE------- 122

  Fly   108 ALFNASNDILSDPGVQRMLHDKSESFDLIIMEPSSLDALYGLVEFYN-----ATLMGLSSIRINW 167
               :....|..|..:.::|.||  .||::|.|......|| |.::..     :...|...|.|.
Worm   123 ---HMCRKIFQDSELHKILKDK--DFDVVIAETFDFCGLY-LADYIQSKSIVSVFTGSRLIAIT- 180

  Fly   168 HTYELAGNPAPSIYEPI-SPVGFSLETSLFSRVYNWIHIMEEKLV---NYLILRPAQLHLFQKFF 228
               :..|.|:...|.|. |...|....|:|.|:.:..|    |.|   .|.|:...|.:...:..
Worm   181 ---DPLGEPSSLHYIPAPSSDNFGSSASIFDRINDLYH----KYVFGSGYSIIFDWQYNQIARLT 238

  Fly   229 GYSAQKMNELRSRFSLMLINSHYSMGKVRANAPNIIEVGGLHLSEPPEPSDEELQ-KFLDKADHG 292
            ....:...::....:....||:..:.........:|.:||..:       |:.:| |..|:.|..
Worm   239 HGKVRHWKKILKDVTYHFANSNPYLDFAAPTISKVIPIGGYDM-------DKSIQTKIPDEFDSI 296

  Fly   293 V------IYFSMGNDILIKFLPENIQELLLQTFA--TLNESIIWKSELLYMPDKSD--------- 340
            :      :|.|.|:.:..||:||:.:|.:|:.|.  |.|.:.:||.|     |.:|
Worm   297 LNERSLTVYVSFGSMVKAKFMPESYKEAMLRMFTANTQNITFLWKYE-----DPTDIFFKNRLPK 356

  Fly   341 NVYVVEQAPQRHILNHPNVRLFITNGGLLSVIEAVDSGVPMLGLPMFFDQFGNMRWVQLSGMAEV 405
            ||.:.:..|||.:|....|:||||:|||.|.:|...:..|.:.:|:..:|..|.:.:...|.||:
Worm   357 NVILKDWFPQRALLADKRVKLFITHGGLGSTMELAYAAKPAIVIPLIAEQPDNGKMLARHGSAEI 421

  Fly   406 MDINSL-NKDTLTETIKHMLANNSYYLKAKEISQFFKDRPMSPLDTAVWWTEYALRNRNITRMRL 469
            ...:.: :.:.|...::.||.::||...|..:::...::|:.|.:..:..:|.|.....:..:..
Worm   422 YSKHDIPHWEKLNRLLQKMLQHSSYQKAADRLARVLSNQPIKPRELMIKHSEMAAMFGKMPELTP 486

  Fly   470 NLEEIPLIEYYRIDSILAF---SLRFGLVAASLIFLVYT 505
            :::::.:||:|.:|.|..|   |:...::....::.|.|
Worm   487 SVQDMSIIEFYNLDIIFLFLIISIGTSVLLWKFLYFVLT 525

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303B1	NP_651153.1	egt	21..462	CDD:223071	114/497 (23%)
Ugt303B1	NP_651153.1	UDPGT	41..511	CDD:278624	121/524 (23%)
ugt-4	NP_001041203.1	egt	1..473	CDD:223071	117/505 (23%)
ugt-4	NP_001041203.1	UDPGT	21..500	CDD:278624	117/516 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.810