DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt303B1 and ugt-5

DIOPT Version :9

Sequence 1:	NP_651153.1	Gene:	Ugt303B1 / 42775	FlyBaseID:	FBgn0039086	Length:	519	Species:	Drosophila melanogaster
Sequence 2:	NP_506200.1	Gene:	ugt-5 / 179753	WormBaseID:	WBGene00013906	Length:	534	Species:	Caenorhabditis elegans

Alignment Length:	565	Identity:	138/565 - (24%)
Similarity:	240/565 - (42%)	Gaps:	82/565 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MRLRYCWLTLSLCLLLQHDRAQAANILGIFPYRHISPFFVMQPLVRTLATRGHNVTLITP--IGM 63
            |.:.:.:|   :.:||......:.|.|.|.|....|....|..:...||..||.||...|  :.:
Worm     1 MNIHHVFL---IFVLLFIKNVASYNFLVISPVYGFSHMKSMAIIANQLADAGHQVTYFQPFVVEL 62

  Fly    64 PNDIEGVRHIRVAQLN----ERIKEMLESDQVLDFMINKWTE--------SALTAKALFNAS--- 113
            ..|.:.:::..:..:|    |..|:.:....||.   :.||.        ..:.|..:.:.|
Worm    63 FKDHDLIKNPNIEIMNYFHDEEGKKNIPGHSVLS---DAWTSYKYQSDVGQKIFAPRILHQSFQE 124

  Fly   114 --NDILSDPGVQRMLHDKSESFDLIIMEPSSLDALYGLVEFYN--ATLMGLSSIRINWHTYELAG 174
              ..:..|..:.|.|.||  .||:::.|......|| |.::..  |.:...:..|:|..|..| |
Worm   125 MCRHMFEDEALHRQLKDK--KFDVVLSETFDFCGLY-LADYLEMPAIISVFTGNRLNAITNAL-G 185

  Fly   175 NPAPSIYEPISPVGFSLETSLFSRVYN-WIHIMEEKLVNYLILRPAQLHLFQKFFG--------- 229
            .|:...|.|.....|:...||:.|..| |..|:......         .||.:.:.
Worm   186 EPSFLHYLPSPSSSFNANMSLYDRFNNFWHKILSSSTFG---------ELFDRQYADVYRLTNGK 241

  Fly   230 --YSAQKMNELRSRFSLMLINSHYSMGKVRANAPNIIEVGG--LHLSEPPEPSDEELQKFLDKAD 290
              :..|.:|::...||    ||:..:..|......:|.:||  :...:.| |..::|...|:...
Worm   242 ARHWKQILNDVTYHFS----NSNPYLDFVIPTIAKVIPIGGYTMDYKQVP-PVSKDLDTILNLRS 301

  Fly   291 HGVIYFSMGNDILIKFLPENIQELLLQTFA-TLNESIIWKSELLYMPDKS-------DNVYVVEQ 347
             ..::.|.|..|..|::|:..::.::..|. ..|.:.:||.|   .|::.       |||::...
Worm   302 -STVFISYGTMISAKYMPDEYKQSMIDFFKDNKNVTFLWKYE---EPEEKFIKENIPDNVHLSTW 362

  Fly   348 APQRHILNHPNVRLFITNGGLLSVIEAVDSGVPMLGLPMFFDQFGNMRWVQLSGMAEVM---DIN 409
            .||:.:|....|:||||:|||.|.:|...|..|.:..|:|.||..|.:.::..|..||:   ||.
Worm   363 FPQQSLLADKRVKLFITHGGLGSTMELAYSAKPAIVTPLFADQPSNAQMLERHGSVEVLSKHDIP 427

  Fly   410 SLNKDTLTETIKHMLANNSYYLKAKEISQFFKDRPMSPLDTAVWWTEYALRNRNITRMRLNLEEI 474
            :..|.  ::.:|.|||:..|...|..::....::|:||.:..:...|.|.|...|..:....:::
Worm   428 NWKKQ--SDLLKTMLADKKYQEAATRLADILNNQPISPRELMLKHAENAARFGKIPSLTPFAKDM 490

  Fly   475 PLIEYYRIDSILAFSLRFGLVAASLIFLVYTLF--LKYRIRLRRL 517
            ..||:|.||.|: :|:.|.|.|   |::...:|  :|...:.|:|
Worm   491 GFIEFYNIDLII-YSVSFTLFA---IYVTIEIFGIVKNCCKTRKL 531

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303B1	NP_651153.1	egt	21..462	CDD:223071	118/486 (24%)
Ugt303B1	NP_651153.1	UDPGT	41..511	CDD:278624	127/517 (25%)
ugt-5	NP_506200.1	egt	6..509	CDD:223071	130/533 (24%)
ugt-5	NP_506200.1	UDPGT	32..527	CDD:278624	128/525 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.810