DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt303B1 and ugt-33

DIOPT Version :9

Sequence 1:	NP_651153.1	Gene:	Ugt303B1 / 42775	FlyBaseID:	FBgn0039086	Length:	519	Species:	Drosophila melanogaster
Sequence 2:	NP_505692.2	Gene:	ugt-33 / 179464	WormBaseID:	WBGene00007946	Length:	522	Species:	Caenorhabditis elegans

Alignment Length:	546	Identity:	133/546 - (24%)
Similarity:	226/546 - (41%)	Gaps:	80/546 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 TLSLCLLLQHDRAQAANILGIFP-YRHISPFFVMQPLVRTLATRGHNVTLITPIGMPNDIEGVRH 72
            ||.||.|......|..|.|...| |.|....|:.: :..||...|||||.:.||.: ...|.|::
Worm     4 TLFLCTLFLVGFVQPFNYLVFCPLYAHSHHKFLAK-IADTLTDAGHNVTFLAPIVL-RKYENVKY 66

  Fly    73 IRVAQLNERIKEML-----ESDQVLDFMINK---WTESALT----------AKALFNASNDILSD 119
            :      |..|:::     :..:.|.|..|.   |||.|..          .|.......|:..|
Worm    67 L------ESTKDIVYIQPSKELEALGFTSNYSKFWTEDATAIQFVPAVRTFVKMFVQLYEDLKKD 125

  Fly   120 PGVQRMLHDKSESFDLIIME---PSSLDALYGLVEFYNATLMGLSSIRINWHTYELAGNPAPSIY 181
            ..|...|  |:.:||.|:.|   |::    :.:.|:.....: |.|:.:..||     ..:..|.
Worm   126 LSVLDEL--KNRNFDAIVFEFLCPTA----FPIAEYLGIKAL-LPSLSMTHHT-----QMSRWIG 178

  Fly   182 EPISPVGFSLETSLFSRVYN-WIHIMEEKLVNYLILRPAQLHLF-----QKFFGYSAQKMN--EL 238
            ||.||.......|.|....| |     |:|.|  .|......||     ...|....:|::  |:
Worm   179 EPSSPTVLPSMISSFGDDMNFW-----ERLGN--TLGDVFFTLFVDMPRMTSFSDPERKIDFYEM 236

  Fly   239 RSRFSLMLINSHYSMGKVRANAPNIIEVGGLHLSE---PPEPSDEELQKFLDKADHGVIYFSMGN 300
            ..|...|.:||:..:...|......:.:||:.::.   ..:..:|:..|.:.:....:: .|.|:
Worm   237 SVRAPFMFMNSNPYLDYARPILTKTVLIGGISVNVTQLKQKKLNEKYDKIISERQQNIL-ISFGS 300

  Fly   301 DILIKFLPENIQELLLQTFATL-NESIIWKSE------LLYMPDKSDNVYVVEQAPQRHILNHPN 358
            .|..|.:|:..:..|:|...:. |.:.|||.|      ..::|    |::..:..||..:|....
Worm   301 MIFSKDMPDVYKNTLVQVIKSFPNVTFIWKYEEDDVSFAKHLP----NLHFSKWVPQTALLADSR 361

  Fly   359 VRLFITNGGLLSVIEAVDSGVPMLGLPMFFDQFGNMRWVQLSGMAEVM---DINSLNKDTLTETI 420
            :..|:|:.||.||.|....|.|.:.:|:|.||..|.:.:.....:..:   |::|..|  |...|
Worm   362 LSAFVTHAGLGSVTELSYMGKPAVLIPLFADQLRNSKTLSRHNGSITLSKYDLSSFEK--LRFAI 424

  Fly   421 KHMLANNSYYLKAKEISQFFKDRPMSPLDTAVWWTEYALRNRNITRMRLNLEEIPLIEYYRIDSI 485
            ..:|.:..|.:.|:.:||..:|:|:||....|...|:..:...:..:.....::..|.:|.:| |
Worm   425 NTILNDERYKINAEILSQQLQDQPVSPHALLVKHAEFGAKYGELPNLDPCSRQMSFISFYMLD-I 488

  Fly   486 LAFSLRFGLVAASL-IFLVYTLFLKY 510
            :.| :.|.|:..:: |.|.....||:
Worm   489 IVF-VGFILITTTIGIVLTVKWILKF 513

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303B1	NP_651153.1	egt	21..462	CDD:223071	117/483 (24%)
Ugt303B1	NP_651153.1	UDPGT	41..511	CDD:278624	121/513 (24%)
ugt-33	NP_505692.2	Glycosyltransferase_GTB_type	1..498	CDD:299143	129/529 (24%)
ugt-33	NP_505692.2	UDPGT	31..520	CDD:278624	122/519 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		otm14625
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.810