DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt303B1 and ugt-2

DIOPT Version :9

Sequence 1:	NP_651153.1	Gene:	Ugt303B1 / 42775	FlyBaseID:	FBgn0039086	Length:	519	Species:	Drosophila melanogaster
Sequence 2:	NP_505672.2	Gene:	ugt-2 / 179450	WormBaseID:	WBGene00007073	Length:	531	Species:	Caenorhabditis elegans

Alignment Length:	543	Identity:	137/543 - (25%)
Similarity:	231/543 - (42%)	Gaps:	78/543 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 CLLLQHDRAQAANILGIFPYRHISPFFVMQPLVRTLATRGHNVTLI-TPIGMPNDIEGVRHIRVA 76
            |.:|.::....|.:.|   |.|:.   .|..:..|||...|||||: |.|     .|....||:.
Worm    15 CNVLAYNYLVVAPVFG---YSHMK---FMNKVADTLANGKHNVTLLQTYI-----YEHWGKIRIV 68

  Fly    77 QLNERIKEMLESDQVLDFMINKWTESALTAKALFNASNDILSDP--GV---------------QR 124
            : |:.| |:::.....:...|:.:.||..    |...|:|:::|  |.               .|
Worm    69 K-NKNI-EIIDYHNSENVPSNEQSASAFK----FFWDNEIVNNPITGAMAPMFILYNEFKPMCDR 127

  Fly   125 MLHDK-------SESFDLIIMEPSSLDALYGLVEFYNATLMGLSSIRINWHTYELAGNP-----A 177
            :|.||       |..||..:.|.....:|| |.:.....|:.:.|...|.......|.|     |
Worm   128 ILTDKELHQWILSNKFDGYVAESFDFCSLY-LGDHLKLNLLPMFSTIKNVPGSHAIGEPSLLNYA 191

  Fly   178 PSIYEPISPVGFSLETSLFSRVYNWIHIMEEKLVNYLILRPAQLHLFQKFFGYSAQKMN------ 236
            ||:|     ..|..:.:::.|:        :.:..:.....|..:||::.:..:...:|
Worm   192 PSLY-----TNFGSDQTVWDRI--------QDITAFTSFHYAFSNLFERQYRQAYDLLNGDVRTW 243

  Fly   237 -ELRSRFSLMLINSHYSMGKVRANAPNIIEVGGLHLSEPPEPS-DEELQKFLDKADHGVIYFSMG 299
             |:....:....|::..:|.........:|:||..:..|.:.| :||..|.||.....|: .|.|
Worm   244 REILQTATYFFYNNNPYIGFAMPTLEKSVEIGGFTIDPPHDLSLNEEFDKLLDLRKSTVL-ISFG 307

  Fly   300 NDILIKFLPENIQELLLQTFATL-NESIIWKSEL---LYMPDKSDNVYVVEQAPQRHILNHPNVR 360
            ..:....:|||.:..|::.||.| :.:.|||.|:   .:....|:||::.:..||..:|..|.:.
Worm   308 TVVQSADMPENFKSGLIKMFAKLPDTTFIWKYEVEDAEFSKTLSENVFLKKWIPQPALLADPRLN 372

  Fly   361 LFITNGGLLSVIEAVDSGVPMLGLPMFFDQFGNMRWVQLSGMAEVMDINSL-NKDTLTETIKHML 424
            ||||:|||.|.:|...:|.|.|.:|:|.||..|.:.:...|.|...|...| |.:.||||:|..:
Worm   373 LFITHGGLGSTLEVAYAGKPSLMIPIFGDQMLNAKMLSRHGGAISYDKYELENYEKLTETVKEAI 437

  Fly   425 ANNSYYLKAKEISQFFKDRPMSPLDTAVWWTEYALRNRNITRMRLNLEEIPLIEYYRIDS---IL 486
            :|..|..||..:::...::|:.|....:...|:..:...:..:.........|:||.:|:   |:
Worm   438 SNKEYNKKALLLAEILHNQPIDPKQNLLKHAEFTAKFGRVHALEPYSVHYNFIKYYMLDAYAIII 502

  Fly   487 AFSLRFGLVAASLIFLVYTLFLK 509
            .|.|....|...:|..||....|
Worm   503 IFFLSILYVLNLIIKFVYRKIFK 525

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303B1	NP_651153.1	egt	21..462	CDD:223071	123/483 (25%)
Ugt303B1	NP_651153.1	UDPGT	41..511	CDD:278624	131/515 (25%)
ugt-2	NP_505672.2	egt	15..498	CDD:223071	129/514 (25%)
ugt-2	NP_505672.2	UDPGT	31..530	CDD:278624	133/524 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.810