Protein Alignment Ugt303B1 and UGT3A1

DIOPT Version :9

• Sequence 1: NP_651153.1
• Gene: Ugt303B1 / 42775
• FlyBaseID: FBgn0039086
• Length: 519
• Species: Drosophila melanogaster
• Sequence 2: NP_689617.3
• Gene: UGT3A1 / 133688
• HGNCID: 26625
• Length: 523
• Species: Homo sapiens
• Alignment Length: 534
• Identity: 129/534 - (24%)
• Similarity: 224/534 - (41%)
• Gaps: 108/534 - (20%)

  Fly    21 AQAANILGIFPYRHISPFFVMQPLVRTLATRGHNVTLITPIG---MPNDIEGVRHIRVAQL---- 78
            ::||.||.|..... |.:.::..:.:.|...|||||::...|   :|:..|..:..:|.:.
Human    20 SEAAKILTISTLGG-SHYLLLDRVSQILQEHGHNVTMLHQSGKFLIPDIKEEEKSYQVIRWFSPE 83

  Fly    79 --NERIKEMLES--DQVLDFMINKWTESALTAKALFNAS-NDILSDPGVQRMLHDKSESFDLIIM 138
              .:|||:..:|  :..||.  .|.:|:.:....:|... :.:||...:...|  |:|::||:.:
Human    84 DHQKRIKKHFDSYIETALDG--RKESEALVKLMEIFGTQCSYLLSRKDIMDSL--KNENYDLVFV 144

  Fly   139 EP-----------------SSLDALYGLVEFYNATLMGLSSIRINWHTYELAGNPAPSIYEPISP 186
            |.                 :.|...:|.::|                     |.|:|..|.|:.|
Human   145 EAFDFCSFLIAEKLVKPFVAILPTTFGSLDF---------------------GLPSPLSYVPVFP 188

  Fly   187 VGFSLETSLFSRVYNWIHIMEEKLVNYLILRPAQLHLFQKFFGYSAQKM-------NELRSRF-- 242
            ...:.....:.||.|                      |..||.:|..:.       |.::..|
Human   189 SLLTDHMDFWGRVKN----------------------FLMFFSFSRSQWDMQSTFDNTIKEHFPE 231

  Fly   243 -------------SLMLINSHYSMGKVRANAPNIIEVGGLHLSEPPEPSDEELQKFL-DKADHGV 293
                         .|..:||.::....|...||.:.:||| :.:|.:|..::|..|: :..|.|.
Human   232 GSRPVLSHLLLKAELWFVNSDFAFDFARPLLPNTVYIGGL-MEKPIKPVPQDLDNFIANFGDAGF 295

  Fly   294 IYFSMGNDILIKFLPENIQELLLQTFATLNESIIWKSELLYMP---DKSDNVYVVEQAPQRHILN 355
            :..:.|: :|.....:.:.:.:...||.|.:.:||..:..:.|   ..:.||.:|:..||..:|.
Human   296 VLVAFGS-MLNTHQSQEVLKKMHNAFAHLPQGVIWTCQSSHWPRDVHLATNVKIVDWLPQSDLLA 359

  Fly   356 HPNVRLFITNGGLLSVIEAVDSGVPMLGLPMFFDQFGNMRWVQLSGMAEVMDINSLNKDTLTETI 420
            ||::|||:|:||..||:||:..||||:|||:..||.|||..|........:.:|.:..||||.|:
Human   360 HPSIRLFVTHGGQNSVMEAIRHGVPMVGLPVNGDQHGNMVRVVAKNYGVSIRLNQVTADTLTLTM 424

  Fly   421 KHMLANNSYYLKAKEISQFFKDRPMSPLDTAVWWTEYALRNRNITRMRLNLEEIPLIEYYRIDSI 485
            |.::.:..|.......|.....:|:||....|.|.::.|:....|.::....:.|..|.|.||
Human   425 KQVIEDKRYKSAVVAASVILHSQPLSPAQRLVGWIDHILQTGGATHLKPYAFQQPWHEQYLID-- 487

  Fly   486 LAFSLRFGLVAASL 499
             .|....||...::
Human   488 -VFVFLLGLTLGTM 500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303B1	NP_651153.1	egt	21..462	CDD:223071	120/495 (24%)
		UDPGT	41..511	CDD:278624	123/514 (24%)
UGT3A1	NP_689617.3	UDPGT	23..523	CDD:330975	128/531 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150066
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.740