Protein Alignment Ugt303B3 and Ugt2a1

DIOPT Version :10

• Sequence 1: NP_651152.1
• Gene: Ugt303B3 / 42774
• FlyBaseID: FBgn0039085
• Length: 539
• Species: Drosophila melanogaster
• Sequence 2: NP_444414.2
• Gene: Ugt2a1 / 94215
• MGIID: 2149905
• Length: 528
• Species: Mus musculus
• Alignment Length: 545
• Identity: 139/545 - (25%)
• Similarity: 228/545 - (41%)
• Gaps: 131/545 - (24%)

  Fly    40 SHNLVVRPLAKALVKRGHNVTLITPVG----MPTDIEGVRHIRVPKLNQRVQEMIEGDQILDFFG 100
            ||.|.|:.:...|:::.||||::...|    .|:.|.       |.|...:..:.        ||
Mouse    31 SHWLNVKIIIDELLRKEHNVTVLVASGALFITPSSIS-------PSLTFEIYPVP--------FG 80

  Fly   101 SKWIASLM---VVSMLYNMSSDILSDKGVQKMLQNRNERFDLVMLEPSALEALY----GVVEHYN 158
            .:.|.|::   |::.|.|..|                         ||.:...|    .|:|.::
Mouse    81 KEKIESVIKDFVLTWLENRPS-------------------------PSTIWTFYKEMAKVIEEFH 120

  Fly   159 ATLMGFSGG---NVNWSTEEVAGNFAPSINDPISSLG------------YSRSNSLLSKIYNWVH 208
            ....|...|   |....::.....|...::||:...|            ||...|..|
Mouse   121 LVSRGICDGVLKNEKLMSKLQKEKFEVLLSDPVFPCGDIVALKLGIPFIYSLRFSPAS------- 178

  Fly   209 ITEEKLLKHLIFRPS-----------QLRIFKKFFNFSEQKFYNMRE------------------ 244
             |.||....:.|.||           |:....:..||..   |.|::
Mouse   179 -TVEKHCGKVPFPPSYVPAILSELTDQMSFTDRVRNFIS---YRMQDYMFETLWKQWDSYYTKAL 239

  Fly   245 -----------KYSVILVNNHISMGRVRSNVPNIIEVGGLHLTEPAEPCDSKLQKFMD-DAEHGV 297
                       |..:.|:..:......|..:||...||||| .:||:|...::::|:. ..|||:
Mouse   240 GRPTTLCETMGKAEIWLMRTYWDFEFPRPYLPNFEFVGGLH-CKPAKPLPKEMEEFVQTSGEHGI 303

  Fly   298 IYFSMGQEIMVQFLPEDMQQNLMKSLDQFKQRVVWKTELYNMPNKSDNVYVIEQPPQRAVLAHPN 362
            :.||:|.  ||:.|.::....:..:|.|..|:|:|:.:.........|..:.:..||..:|.||.
Mouse   304 VVFSLGS--MVKNLTDEKANLIASALAQIPQKVLWRYKGKIPDTLGSNTRLFDWIPQNDLLGHPK 366

  Fly   363 TRLFITNGGLLSVMEAVYSGVPILGLPVFFDQFINLRNVNLRGMAEVLDANEMTLEILTSTIRKL 427
            ||.|||:||...:.||:|.|:|::|:|:|.||..|:.::..:|.|..::.|.||...|.:.:|.:
Mouse   367 TRAFITHGGTNGIYEAIYHGIPMVGVPMFADQPDNIAHMKAKGAAVEVNMNTMTSSDLLNALRTV 431

  Fly   428 LENPRYALKAKKMSQSFRDRPMSPLDTAVWWTEYALRNKDASHMRLNTEDVP--LYYEWDWGLLL 490
            :..|.|...|.::|:...|:|:.|||.||:|.|:.:|:|.|.|:|:...|:.  .|:..|   ::
Mouse   432 INEPSYKENAMRLSRIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAHDLSWFQYHSLD---VI 493

  Fly   491 GLRFGIVFGSVIYLVYK----LFQK 511
            |.....| .|.|.||.|    :|||
Mouse   494 GFLLACV-ASAILLVAKCCLFIFQK 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303B3	NP_651152.1	GT1_Gtf-like	28..458	CDD:340817	119/484 (25%)
Ugt2a1	NP_444414.2	UDPGT	21..516	CDD:278624	136/542 (25%)