DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt303B3 and Ugt305A1

DIOPT Version :9

Sequence 1:	NP_651152.1	Gene:	Ugt303B3 / 42774	FlyBaseID:	FBgn0039085	Length:	539	Species:	Drosophila melanogaster
Sequence 2:	NP_001261394.1	Gene:	Ugt305A1 / 59217	FlyBaseID:	FBgn0042179	Length:	583	Species:	Drosophila melanogaster

Alignment Length:	582	Identity:	130/582 - (22%)
Similarity:	244/582 - (41%)	Gaps:	118/582 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 FCLFLQKDLYQDSVQAANILGIFSYHFSSHNLV--VRPLAKALVKRGHNVTLITPVGMP---TDI 71
            ||          |::|||||.:.|  .:.||..  .:||..||:..||::.:|:....|   ..:
  Fly    16 FC----------SLEAANILCLVS--TAKHNNPGWSKPLFDALLANGHSLLVISTAPNPEPKKQV 68

  Fly    72 EGVRHIRVPK---------LNQRVQE---MIEGDQILDFFGSKWIASLMVVSMLYNMSSDILSDK 124
            :|:.:..:|.         |.:..:|   |:..:|:|.::      .:::.|....::||.:|.|
  Fly    69 DGLVYYHLPNEYDVMKRHFLLEEPREYISMVTLNQLLVWY------EVLLGSCRALLNSDTMSSK 127

  Fly   125 GVQKMLQNRNERFDLVMLEPSALEALYGVVEHYNATLMGFSGGNVNWSTEEVAGNFAPSINDPIS 189
            ..:...|...| :||::.:         |.:.....:...||    |.::.|.|..|..:...:.
  Fly   128 RPELTAQLSME-YDLIITD---------VTQGIECLMDSVSG----WRSKPVLGLSAGKLTPDLM 178

  Fly   190 SL-----------------GYSRSNSLLSKIYNWVHITEEKLLKHLIFRPSQLRIFKKFFNFSEQ 237
            ||                 ...::....::::|.:....|.|:..:|.||....:.|     :|.
  Fly   179 SLLRAENTINAARIPHYISQVPKTMGFWNRLHNHIMYYAEPLIHLVITRPVLSELMK-----TEN 238

  Fly   238 KFYNMREKYSVILVNNHISMGRVRSNVPNIIEVGGLHLTEPAEPCDSKLQKFMDDAEHGVIYFSM 302
            .|    .|..::|:|.|.::..|::..|.:|||||||:.....|..:.:|:|.:....|::|.:|
  Fly   239 AF----PKLQLVLLNTHPTLDYVQNLPPGVIEVGGLHIKNQTSPLPTYIQEFTEKFFDGIVYINM 299

  Fly   303 GQEIMVQFLPEDMQQNLMKSLDQFKQRV--VWKTE-LYNMPNKSDNVYV--IEQPPQRAVLAHPN 362
            .   .:::: .|.....|.::......|  :|..| |..:|.|..|:..  :.|..|:.:||...
  Fly   300 P---YIEYM-NDQGLKAMYTMIHGNPNVAFIWNVEQLEQLPAKKPNLLTLHVNQSLQQDILAMQY 360

  Fly   363 TRLFITNGGLLSVMEAVYSGVPILGLPVFFDQFINLRNVNLRGMAEVLDANEMTLEILTSTIRKL 427
            .:.|:.:|...|:.||::.|||::.||:..::|.|.:.|..|.:..:|...|.....|:..:.::
  Fly   361 VKGFLNHGDSFSLQEAIHYGVPVVVLPLKLEEFNNAQRVMERNLGVMLQVKEFNQSSLSDALTRI 425

  Fly   428 LENPRYALKAKKMSQSFRDRPMSPLDTAVWWTEYALRNKDASHMRLNTE---------------D 477
            |:..|:.....:....||.||.|.|:.|||..|..:...........||               .
  Fly   426 LDEERFISALHQAQLKFRTRPQSALELAVWHAEQLIAEPRLFKHFAQTETLAQNFFVANSLDVLT 490

  Fly   478 VPLYYEWDWGLLLGLRFGIVFGSVIYLVYKLFQKTSARRRPFQVTGTVSQHPSLLDRRSQTQ 539
            ||         |:.|...:|  |:..|||.|:...|.|::..:        .::|.:|.:::
  Fly   491 VP---------LIVLLAAVV--SLANLVYVLYTGGSKRQQTLE--------KAVLKKRKKSK 533

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303B3	NP_651152.1	egt	7..466	CDD:223071	114/492 (23%)
Ugt305A1	NP_001261394.1	Glycosyltransferase_GTB_type	<242..461	CDD:299143	61/222 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45445812
Domainoid	1	1.000	76	1.000	Domainoid score	I3136
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	89	1.000	Inparanoid score	I2281
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D53444at6656
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR48043
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	7.000