Protein Alignment Ugt303B3 and UGT1A9

DIOPT Version :10

• Sequence 1: NP_651152.1
• Gene: Ugt303B3 / 42774
• FlyBaseID: FBgn0039085
• Length: 539
• Species: Drosophila melanogaster
• Sequence 2: NP_066307.1
• Gene: UGT1A9 / 54600
• HGNCID: 12541
• Length: 530
• Species: Homo sapiens
• Alignment Length: 493
• Identity: 127/493 - (25%)
• Similarity: 234/493 - (47%)
• Gaps: 48/493 - (9%)

  Fly    40 SHNLVVRPLAKALVKRGHNVTLITP-----VGMPTDIEGVRHIRVPKLNQRVQEMIEGDQILD-- 97
            ||...:|.:.:.|:.|||.|.::.|     :|.             .||..|:.......:.|
Human    36 SHWFTMRSVVEKLILRGHEVVVVMPEVSWQLGR-------------SLNCTVKTYSTSYTLEDLD 87

  Fly    98 -----FFGSKWIASL-MVVSMLYNMSSDI-----------LSDKGVQKMLQNRNERFDLVMLEPS 145
                 |..::|.|.: .:.|:|....:||           ..||.:.:.|  :...||.|.|:|.
Human    88 REFKAFAHAQWKAQVRSIYSLLMGSYNDIFDLFFSNCRSLFKDKKLVEYL--KESSFDAVFLDPF 150

  Fly   146 ALEALYGVVEHYNATLMGFSGGNVNWSTEEVAGNFAPSINDPISSLGYSRSNSLLSKIYNWVHIT 210
            ....|. |.::::...:.|:.|.:....||.|...||....|...||:|.:.:...::.|.:...
Human   151 DNCGLI-VAKYFSLPSVVFARGILCHYLEEGAQCPAPLSYVPRILLGFSDAMTFKERVRNHIMHL 214

  Fly   211 EEKLLKHLIFRPSQLRIFKKFFNFSEQKFYNMREKYSVILVNNHISMGRVRSNVPNIIEVGGLHL 275
            ||.||.|..|: :.|.|..:.......: |::....|:.|:.....:...:..:||:|.:||::.
Human   215 EEHLLCHRFFK-NALEIASEILQTPVTE-YDLYSHTSIWLLRTDFVLDYPKPVMPNMIFIGGINC 277

  Fly   276 TEPAEPCDSKLQKFMD-DAEHGVIYFSMGQEIMVQFLPEDMQQNLMKSLDQFKQRVVWKTELYNM 339
            .: .:|...:.:.::: ..|||::.||:|.  ||..:||.....:..:|.:..|.|:|:......
Human   278 HQ-GKPLPMEFEAYINASGEHGIVVFSLGS--MVSEIPEKKAMAIADALGKIPQTVLWRYTGTRP 339

  Fly   340 PNKSDNVYVIEQPPQRAVLAHPNTRLFITNGGLLSVMEAVYSGVPILGLPVFFDQFINLRNVNLR 404
            .|.::|..:::..||..:|.||.||.|||:.|...|.|::.:|||::.:|:|.||..|.:.:..:
Human   340 SNLANNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETK 404

  Fly   405 GMAEVLDANEMTLEILTSTIRKLLENPRYALKAKKMSQSFRDRPMSPLDTAVWWTEYALRNKDAS 469
            |....|:..|||.|.|.:.::.::.:..|.....::|...:|||:.|||.||:|.|:.:|:|.|.
Human   405 GAGVTLNVLEMTSEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAP 469

  Fly   470 HMRLNTEDVPLYYEWDWGLLLGLRFGIVFGSVIYLVYK 507
            |:|....|: .:|::....::|....:|. :|.::.:|
Human   470 HLRPAAHDL-TWYQYHSLDVIGFLLAVVL-TVAFITFK 505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303B3	NP_651152.1	GT1_Gtf-like	28..458	CDD:340817	114/442 (26%)
UGT1A9	NP_066307.1	UDPGT	26..521	CDD:278624	127/493 (26%)