Protein Alignment Ugt303B3 and UGT1A5

DIOPT Version :9

• Sequence 1: NP_651152.1
• Gene: Ugt303B3 / 42774
• FlyBaseID: FBgn0039085
• Length: 539
• Species: Drosophila melanogaster
• Sequence 2: NP_061951.1
• Gene: UGT1A5 / 54579
• HGNCID: 12537
• Length: 534
• Species: Homo sapiens
• Alignment Length: 497
• Identity: 124/497 - (24%)
• Similarity: 236/497 - (47%)
• Gaps: 55/497 - (11%)

  Fly    40 SHNLVVRPLAKALVKRGHNVTLIT-PVGMPTDIEGVRHIRVPKLNQRVQEMIEGDQIL-----DF 98
            ||.|.:|...:.|..|||.|.::| .|.|....|....:....::....|.   |::|     .|
Human    39 SHWLSMREALRDLHARGHQVVVLTLEVNMYIKEENFFTLTTYAISWTQDEF---DRLLLGHTQSF 100

  Fly    99 FGSKWIASLMVVS----MLYNMSSDILSDKGVQKMLQN-------RNERFDLVMLEPSALEALYG 152
            |.::.:  ||..|    ::.|||  ::..:...::|.|       ....||:|:.:|..|.|  .
Human   101 FETEHL--LMKFSRRMAIMNNMS--LIIHRSCVELLHNEALIRHLHATSFDVVLTDPFHLCA--A 159

  Fly   153 VVEHYNATLMGFSGGNVNWSTEEVAGNFAPSINDPISSLGYSRSN--SLLSKIYNWVHITEEKLL 215
            |:..|.:....|...|:.... :..|...|:.:..|..|..:.|:  :.|.::.|.::......|
Human   160 VLAKYLSIPAVFFLRNIPCDL-DFKGTQCPNPSSYIPRLLTTNSDHMTFLQRVKNMLYPLALSYL 223

  Fly   216 KHLIFRPSQLRIFKKFFNFSEQKFYNMREKYSVILVNNHISMGRVRSN---------VPNIIEVG 271
            .|.:..|        :.:.:.:.|   :.:.||:.:.:|.|:...|.:         :||::.:|
Human   224 CHAVSAP--------YASLASELF---QREVSVVDLVSHASVWLFRGDFVMDYPRPIMPNMVFIG 277

  Fly   272 GLHLTEPAEPCDSKLQKFMD-DAEHGVIYFSMGQEIMVQFLPEDMQQNLMKSLDQFKQRVVWKTE 335
            |::... .:|...:.:.::: ..|||::.||:|.  ||..:||.....:..:|.:..|.|:|:..
Human   278 GINCAN-GKPLSQEFEAYINASGEHGIVVFSLGS--MVSEIPEKKAMAIADALGKIPQTVLWRYT 339

  Fly   336 LYNMPNKSDNVYVIEQPPQRAVLAHPNTRLFITNGGLLSVMEAVYSGVPILGLPVFFDQFINLRN 400
            .....|.::|..:::..||..:|.||.||.|||:.|...|.|::.:|||::.:|:|.||..|.:.
Human   340 GTRPSNLANNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKR 404

  Fly   401 VNLRGMAEVLDANEMTLEILTSTIRKLLENPRYALKAKKMSQSFRDRPMSPLDTAVWWTEYALRN 465
            :..:|....|:..|||.|.|.:.::.::.:..|.....::|...:|||:.|||.||:|.|:.:|:
Human   405 METKGAGVTLNVLEMTSEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRH 469

  Fly   466 KDASHMRLNTEDVPLYYEWDWGLLLGLRFGIVFGSVIYLVYK 507
            |.|.|:|....|: .:|::....::|....:|. :|.::.:|
Human   470 KGAPHLRPAAHDL-TWYQYHSLDVIGFLLAVVL-TVAFITFK 509

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303B3	NP_651152.1	egt	7..466	CDD:223071	114/454 (25%)
UGT1A5	NP_061951.1	UDPGT	29..525	CDD:278624	124/497 (25%)
		egt	<262..508	CDD:223071	71/250 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150592
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BDT1
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.740