Protein Alignment Ugt303B3 and UGT1A10

DIOPT Version :9

• Sequence 1: NP_651152.1
• Gene: Ugt303B3 / 42774
• FlyBaseID: FBgn0039085
• Length: 539
• Species: Drosophila melanogaster
• Sequence 2: NP_061948.1
• Gene: UGT1A10 / 54575
• HGNCID: 12531
• Length: 530
• Species: Homo sapiens
• Alignment Length: 481
• Identity: 121/481 - (25%)
• Similarity: 235/481 - (48%)
• Gaps: 24/481 - (4%)

  Fly    40 SHNLVVRPLAKALVKRGHNVTLITPVGMPTDIEGVRHIRVPKLNQRVQEMIEGDQILDFFGSKWI 104
            ||...::.:.:.|:.|||.|.::.| .:...:|...:..|...:.......:..:.:.|..::|.
Human    36 SHWFTMQSVVEKLILRGHEVVVVMP-EVSWQLERSLNCTVKTYSTSYTLEDQNREFMVFAHAQWK 99

  Fly   105 ASLM-VVSMLYNMSSDIL-----------SDKGVQKMLQNRNERFDLVMLEPSALEALYGVVEHY 157
            |... :.|:|.:.||..|           :|:.:.:.|  :...||.|.|:|.....|. |.:::
Human   100 AQAQSIFSLLMSSSSGFLDLFFSHCRSLFNDRKLVEYL--KESSFDAVFLDPFDTCGLI-VAKYF 161

  Fly   158 NATLMGFSGGNVNWSTEEVAGNFAPSINDPISSLGYSRSNSLLSKIYNWVHITEEKLLKHLIFRP 222
            :...:.|:.|......||.|...||....|...||:|.:.:...:::|.:...|:.|....:||
Human   162 SLPSVVFTRGIFCHHLEEGAQCPAPLSYVPNDLLGFSDAMTFKERVWNHIVHLEDHLFCQYLFR- 225

  Fly   223 SQLRIFKKFFNFSEQKFYNMREKYSVILVNNHISMGRVRSNVPNIIEVGGLHLTEPAEPCDSKLQ 287
            :.|.|..:... :....|::....|:.|:.....:...:..:||:|.:||::..: .:|...:.:
Human   226 NALEIASEILQ-TPVTAYDLYSHTSIWLLRTDFVLDYPKPVMPNMIFIGGINCHQ-GKPLPMEFE 288

  Fly   288 KFMD-DAEHGVIYFSMGQEIMVQFLPEDMQQNLMKSLDQFKQRVVWKTELYNMPNKSDNVYVIEQ 351
            .::: ..|||::.||:|.  ||..:||.....:..:|.:..|.|:|:.......|.::|..:::.
Human   289 AYINASGEHGIVVFSLGS--MVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKW 351

  Fly   352 PPQRAVLAHPNTRLFITNGGLLSVMEAVYSGVPILGLPVFFDQFINLRNVNLRGMAEVLDANEMT 416
            .||..:|.||.||.|||:.|...|.|::.:|||::.:|:|.||..|.:.:..:|....|:..|||
Human   352 LPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMT 416

  Fly   417 LEILTSTIRKLLENPRYALKAKKMSQSFRDRPMSPLDTAVWWTEYALRNKDASHMRLNTEDVPLY 481
            .|.|.:.::.::.:..|.....::|...:|||:.|||.||:|.|:.:|:|.|.|:|....|: .:
Human   417 SEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAHDL-TW 480

  Fly   482 YEWDWGLLLGLRFGIVFGSVIYLVYK 507
            |::....::|....:|. :|.::.:|
Human   481 YQYHSLDVIGFLLAVVL-TVAFITFK 505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303B3	NP_651152.1	egt	7..466	CDD:223071	111/438 (25%)
UGT1A10	NP_061948.1	UDPGT	26..521	CDD:278624	121/481 (25%)
		egt	<258..504	CDD:223071	72/250 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150360
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BDT1
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.640