DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt303B3 and Ugt37C2

DIOPT Version :9

Sequence 1:	NP_651152.1	Gene:	Ugt303B3 / 42774	FlyBaseID:	FBgn0039085	Length:	539	Species:	Drosophila melanogaster
Sequence 2:	NP_001260516.1	Gene:	Ugt37C2 / 53513	FlyBaseID:	FBgn0040262	Length:	523	Species:	Drosophila melanogaster

Alignment Length:	490	Identity:	147/490 - (30%)
Similarity:	246/490 - (50%)	Gaps:	57/490 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 SVQAANILGIFSYHFSSHNLVVRPLAKALVKRGHNVTLITPVGMPTDIEGVRHIRVPKLNQRVQE 88
            |.|.|||||:||.|..||.::...:||||||.|||||:::.:......:.:..|.||...:  ||
  Fly    17 STQGANILGLFSSHSPSHLIIHMSVAKALVKAGHNVTVVSMLKPKVTHKDIHLIVVPMKEE--QE 79

  Fly    89 MIEGDQILDFFGSK-WIASLMV-----VSMLYNMSSDILSDKGVQKMLQNRNERFDLVMLEPSAL 147
            .|..||:.:..|.| .:.|.|.     :.::.|..:::|||...|::.:.   :|||::|.....
  Fly    80 RIMEDQMTEMAGQKNSLVSTMYRLLTSMDVMINAQAELLSDPRFQRIYET---KFDLMILGYFIN 141

  Fly   148 EALYGVVEHYNATLMGFSGGNVNW------STEEVAGN-----FAPSINDPISS-LGYSR--SNS 198
            :...||.......::      :||      :.::..||     :.|.:....:. :|:.:  .|:
  Fly   142 DFQLGVAHKLKVPVI------INWMSAPVPAIDKYTGNPSELSYVPLMGTVATQPMGFLKRTENA 200

  Fly   199 LLSKIYNWVHITEEKLLKHLIFRPSQLRIFKKFFNFSEQ---KFYNMREKYSVILVNNH-ISMGR 259
            |.|.::.::.:         :|.....||:...  |.||   ....:|:..|:..|.:| ||.|.
  Fly   201 LKSLLFEFIFV---------VFDYKLTRIYNDV--FPEQDMPTLKELRKNISMAFVGSHLISEGP 254

  Fly   260 VRSNVPNIIEVGGLHLTEPAEPCDSKLQKFMDDAEHGVIYFSMGQEIMVQFLPEDMQQNLMKSLD 324
            :|..||.:||:||:.:.:..:|....:.:|:.:|:.|.::.|:|..:....:..::.|.:.|.|.
  Fly   255 IRPLVPALIEIGGIQVKDKPDPLPKDIDQFISNAKQGAVFLSLGSNVKSSTVRPEIVQIIFKVLS 319

  Fly   325 QFKQRVVWKTE-LYNMPNKSDNVYVIEQPPQRAVLAHPNTRLFITNGGLLSVMEAVYSGVPILGL 388
            :.|:.|:||.| |.|.|..|.|:......||..:||||||:||||:.|...:.||.|.|||::.|
  Fly   320 ELKENVIWKWEDLENTPGNSSNILYKNWLPQDDILAHPNTKLFITHAGKGGITEAQYHGVPMVAL 384

  Fly   389 PVFFDQFINLRNVNLRGMAEVLDANEMTLEILTSTIRKLLENPRYALKAKKMSQSFRDRPMSPLD 453
            |:|.||..|...:...|....||...:|.:.|...::::|||.:|.....:.|..:|||||:...
  Fly   385 PIFGDQPGNAALMEKSGYGLALDLLSITEDSLRDALKEVLENQKYKQAIGQFSTLYRDRPMTAKQ 449

  Fly   454 TAVWWTEYALRNKDAS-------HM---RLNTEDV 478
            :.|:||||.||::.|.       ||   :||..|:
  Fly   450 SVVFWTEYILRHQGAPNLQSPSVHMNFIQLNNLDI 484

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303B3	NP_651152.1	egt	7..466	CDD:223071	141/466 (30%)
Ugt37C2	NP_001260516.1	egt	1..467	CDD:223071	142/471 (30%)
Ugt37C2	NP_001260516.1	UDPGT	33..515	CDD:278624	137/474 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45445684
Domainoid	1	1.000	76	1.000	Domainoid score	I3136
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D53444at6656
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		otm14789
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	1	1.100	-	-	P	PTHR48043
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
	9	8.850