Protein Alignment Ugt303B3 and Ugt1a3

DIOPT Version :10

• Sequence 1: NP_651152.1
• Gene: Ugt303B3 / 42774
• FlyBaseID: FBgn0039085
• Length: 539
• Species: Drosophila melanogaster
• Sequence 2: NP_958827.1
• Gene: Ugt1a3 / 396551
• RGDID: 1549728
• Length: 531
• Species: Rattus norvegicus
• Alignment Length: 507
• Identity: 127/507 - (25%)
• Similarity: 240/507 - (47%)
• Gaps: 75/507 - (14%)

  Fly    40 SHNLVVRPLAKALVKRGHNVTLITPVGMPTDIEGVRHIR-----------VPKLNQRVQEMIEGD 93
            ||.|.:|.:.:.|..|||...::.|       |...||:           ||...:..:..:.|
  Rat    36 SHWLSMRDVVRELHARGHQAVVLAP-------EVTVHIKEEDFFTLQTYPVPYTKEEYRHHLLG- 92

  Fly    94 QILDFFGSKWIASLMVVSM--LYNMSS-DILSDKGV---QKMLQNRN-ERFDLVMLEP----SAL 147
            .:.:||.:::...|::..|  :.|:|: .:.|.:|:   ..::|:.| ..||:|:.:|    .|:
  Rat    93 HLQNFFETEFSLKLVLQRMAAVNNVSTFYVRSCRGLLHNTALIQSLNSSSFDVVLTDPFFPCGAV 157

  Fly   148 EALY---GVVEHYNATL--MGFSGGNVNWSTEEVAGNFAPSINDPISSLGYSRSN--SLLSKIYN 205
            .|:|   ..|....:.|  :.|...|            :|:.:..|..|....|:  |.|.::.|
  Rat   158 LAMYLRVPAVFFLQSMLCELEFEATN------------SPNPSSYIPRLLTLNSDHMSFLDRVKN 210

  Fly   206 WVHITEEKLLKHLIFRPSQLRIFKKFFNFSEQKFYNMREKYSVILVNNHISMGRVRSN------- 263
            .::......|.|:.: .|..|:....          ::.:.||:.:..|.|:..:|.:
  Rat   211 MLYPVPWMYLCHVNY-GSLARLASDL----------LQREVSVVEILRHASVWLLRKDFVFYYPR 264

  Fly   264 --VPNIIEVGGLHLTEPAEPCDSKLQKFMD-DAEHGVIYFSMGQEIMVQFLPEDMQQNLMKSLDQ 325
              :||::.:||::... .:|...:.:.::: ..|||::.||:|.  ||..:||.....:.::|.:
  Rat   265 PFMPNMVFIGGINCAN-RKPLSQEFEAYVNASGEHGIVVFSLGS--MVSEIPEKKAMEIAEALGR 326

  Fly   326 FKQRVVWKTELYNMPNKSDNVYVIEQPPQRAVLAHPNTRLFITNGGLLSVMEAVYSGVPILGLPV 390
            ..|.|:|:.......|.:.|..:::..||..:|.||..|.|||:.|...:.|.:.:|||::.:|:
  Rat   327 IPQTVLWRYTGTRPSNLAKNTILVKWLPQNDLLGHPKARAFITHSGSHGIYEGICNGVPMVMMPL 391

  Fly   391 FFDQFINLRNVNLRGMAEVLDANEMTLEILTSTIRKLLENPRYALKAKKMSQSFRDRPMSPLDTA 455
            |.||..|.:.:..||....|:..|||.:.|.:.::.::.|..|.....::|...:|||:.|||.|
  Rat   392 FGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSYKENIMRLSSLHKDRPIEPLDLA 456

  Fly   456 VWWTEYALRNKDASHMRLNTEDVPLYYEWDWGLLLGLRFGIVFGSVIYLVYK 507
            |:|.||.:|:|.|.|:|....|: .:|::....::|....||. :|:::|||
  Rat   457 VFWVEYVMRHKGAPHLRPAAHDL-TWYQYHSLDVIGFLLAIVL-TVVFIVYK 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303B3	NP_651152.1	GT1_Gtf-like	28..458	CDD:340817	110/456 (24%)
Ugt1a3	NP_958827.1	UDPGT	26..522	CDD:278624	127/507 (25%)