Protein Alignment Ugt303B3 and Ugt1a2

DIOPT Version :10

• Sequence 1: NP_651152.1
• Gene: Ugt303B3 / 42774
• FlyBaseID: FBgn0039085
• Length: 539
• Species: Drosophila melanogaster
• Sequence 2: NP_958826.1
• Gene: Ugt1a2 / 396527
• RGDID: 1549741
• Length: 533
• Species: Rattus norvegicus
• Alignment Length: 515
• Identity: 128/515 - (24%)
• Similarity: 234/515 - (45%)
• Gaps: 91/515 - (17%)

  Fly    40 SHNLVVRPLAKALVKRGHNVTLITP---VGMP-TDIEGVRHIRVPKLNQRVQEMIEGDQ------ 94
            ||.|.:|.:.:.|..|||...::.|   |.|. .|...::....|...:..|..|.|:.
  Rat    38 SHWLSMRDVVRELHARGHQAVVLAPEVTVHMKGEDFFTLQTYAFPYTKEEYQREILGNAKKGFEP 102

  Fly    95 ---ILDFFGSKWIASLMVVSMLY-NMSSDILSDKGVQKMLQNRNERFDLVMLEP----SALEALY 151
               :..||  :.:||:.....|| |..:.:|.:|.:.:.|.:.:  ||:|:.:|    .||.|.|
  Rat   103 QHFVKTFF--ETMASIKKFFDLYANSCAALLHNKTLIQQLNSSS--FDVVLTDPVFPCGALLAKY 163

  Fly   152 --------------GVVEHYNATLMGFSGGNVNWSTEEVAGNFAPSINDPISSLGYSRSNSLLSK 202
                          |:  .|.||..            ....::.|::...:|.     ..:.|.:
  Rat   164 LQIPAVFFLRSVPCGI--DYEATQC------------PKPSSYIPNLLTMLSD-----HMTFLQR 209

  Fly   203 IYNWVHITEEKLLKHLIFRP-----SQLRIFKKFFNFSEQKFYNMREKYSVILVNNHISMGRVRS 262
            :.|.::....|.:.||...|     |:|                ::.:.|::.|.:|.|:...|.
  Rat   210 VKNMLYPLTLKYICHLSITPYESLASEL----------------LQREMSLVEVLSHASVWLFRG 258

  Fly   263 N---------VPNIIEVGGLHLTEPAEPCDSKLQKFMD-DAEHGVIYFSMGQEIMVQFLPEDMQQ 317
            :         :||::.:||::.. ..:|...:.:.::: ..|||::.||:|.  ||..:||....
  Rat   259 DFVFDYPRPIMPNMVFIGGINCV-IKKPLSQEFEAYVNASGEHGIVVFSLGS--MVSEIPEKKAM 320

  Fly   318 NLMKSLDQFKQRVVWKTELYNMPNKSDNVYVIEQPPQRAVLAHPNTRLFITNGGLLSVMEAVYSG 382
            .:.::|.:..|.|:|:.......|.:.|..:::..||..:|.||..|.|||:.|...:.|.:.:|
  Rat   321 EIAEALGRIPQTVLWRYTGTRPSNLAKNTILVKWLPQNDLLGHPKARAFITHSGSHGIYEGICNG 385

  Fly   383 VPILGLPVFFDQFINLRNVNLRGMAEVLDANEMTLEILTSTIRKLLENPRYALKAKKMSQSFRDR 447
            ||::.:|:|.||..|.:.:..||....|:..|||.:.|.:.::.::.|..|.....::|...:||
  Rat   386 VPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSYKENIMRLSSLHKDR 450

  Fly   448 PMSPLDTAVWWTEYALRNKDASHMRLNTEDVPLYYEWDWGLLLGLRFGIVFGSVIYLVYK 507
            |:.|||.||:|.||.:|:|.|.|:|....|: .:|::....::|....||. :|:::|||
  Rat   451 PIEPLDLAVFWVEYVMRHKGAPHLRPAAHDL-TWYQYHSLDVIGFLLAIVL-TVVFIVYK 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303B3	NP_651152.1	GT1_Gtf-like	28..458	CDD:340817	111/464 (24%)
Ugt1a2	NP_958826.1	UDPGT	28..524	CDD:278624	128/515 (25%)