DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt303B3 and Ugt36D1

DIOPT Version :9

Sequence 1:	NP_651152.1	Gene:	Ugt303B3 / 42774	FlyBaseID:	FBgn0039085	Length:	539	Species:	Drosophila melanogaster
Sequence 2:	NP_001246082.2	Gene:	Ugt36D1 / 35138	FlyBaseID:	FBgn0032713	Length:	519	Species:	Drosophila melanogaster

Alignment Length:	518	Identity:	138/518 - (26%)
Similarity:	253/518 - (48%)	Gaps:	34/518 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 WLAVLFCLFLQKDLYQ--DSVQAA---NILGIFSYHFSSHNLVVRPLAKALVKRGHNVTLITPVG 66
            |...:..|||...|.|  :.|:||   .:||:|.:...||.....|:.|.|.:.||:|::::..
  Fly     2 WSPRVALLFLALALSQPDELVEAAGPLKVLGLFPHPGVSHFHFFHPIMKGLAEAGHDVSVVSHF- 65

  Fly    67 MPTDIEGVRHIR------VPKLNQRVQEMIEGDQILDFFGSK-WIASLMVVSMLYNMSSD----I 120
              .|...|.|.:      :.||...|.        |.||..: :.:......:||:....    .
  Fly    66 --PDKHPVAHYKDFPLTGMDKLTNSVD--------LKFFEKRTFYSHFQEFFLLYDWGKQTCNLT 120

  Fly   121 LSDKGVQKMLQNRNERFDLVMLEPSALEALYGVVEHYNATLMGFSG-GNVNWSTEEVAGNFAPSI 184
            |..:.:|::|: |..|||::::|....:.:.||.....|.::..|. ..:.|..|.:.....||
  Fly   121 LRSEALQQILR-RPGRFDVIIMEQFNTDCMMGVAHQLQAPVIALSSCVMMPWHYERMGAPLIPS- 183

  Fly   185 NDPISSLGYSRSNSLLSKIYNWVHITEEKLLKHLIFRPSQLRIFKKFFNFSEQKFYNMREKYSVI 249
            :.|...:..|:..:...::.||........:..|:..|:...:.:..|.........:.:..|:.
  Fly   184 HIPALFMAQSQHMNFGGRLANWFSTHALNWMYKLLSVPAADAMVQYKFGHDVPSVGELVKNTSMF 248

  Fly   250 LVNNHISMGRVRSNVPNIIEVGGLHLTEPAEPCDSKLQKFMDDAEHGVIYFSMGQEIMVQFLPED 314
            .||.|.|:...:...||:||:||:|: :.::|..:.||:.:|:||.|||..|.|..|....|...
  Fly   249 FVNQHYSLSGPKVTPPNVIELGGIHI-QKSKPLPADLQRILDNAEEGVILISWGSMIRANSLSAA 312

  Fly   315 MQQNLMKSLDQFKQRVVWKTELYNMPNKSDNVYVIEQPPQRAVLAHPNTRLFITNGGLLSVMEAV 379
            .:..:::::.:.||:|:||.|...:||:..|:::::..|||.:|.|||.::|:::|||:...||.
  Fly   313 KRDGIIRAVARLKQKVIWKWENETLPNQPPNMHIMKWLPQRDILCHPNVKVFMSHGGLMGTSEAA 377

  Fly   380 YSGVPILGLPVFFDQFINLRNVNLRGMAEVLDANEMTLEILTSTIRKLLENPRYALKAKKMSQSF 444
            |.|||::..|::.|||:|...:..|||..:|:..::....:...::|.|:. ::...||.:|.||
  Fly   378 YCGVPVVATPMYGDQFVNTAALVERGMGTILNFEDIGENTVMRALKKALDK-KFHDAAKVVSHSF 441

  Fly   445 RDRPMSPLDTAVWWTEYALRNKDASHMRLNTEDVP--LYYEWDWGLLLGLRFGIVFGSVIYLV 505
            ..||...|.||:||.|:......|..::.:..::.  :||..|...:|.|..|.:..|.::|:
  Fly   442 HHRPQQALHTAIWWVEHVAHTGGAPLLKPSAVEMSRFVYYSLDVYAVLALVLGSIIASWVWLL 504

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt303B3	NP_651152.1	egt	7..466	CDD:223071	129/475 (27%)
Ugt36D1	NP_001246082.2	egt	21..482	CDD:223071	125/475 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45454597
Domainoid	1	1.000	76	1.000	Domainoid score	I3136
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	89	1.000	Inparanoid score	I2281
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		otm14789
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	1	1.100	-	-	P	PTHR48043
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
	9	8.890